Design Study of the Absorber Detector of a Compton Camera for On-Line Control in Ion Beam Therapy

Richard, M.-H.; Dahoumane, M.; Dauvergne, D.; Rydt, M. De; Dedes, G.; Freud, N.; Krimmer, J.; Létang, J M; Lojacono, X.; Maxim, Voichiţa; Montarou, G.; Ray, C.; Roellinghoff, F.; Testa, É.; Walenta, A.H.

doi:10.1109/tns.2012.2206053

Cited by 24 publications

(20 citation statements)

References 16 publications

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“…Polf et al showed the feasibility of using a prototype CC to image PG rays emitted during proton beam irradiation. Because a coincidence event (i.e., the PG interacts with both the scatterer and absorber detectors) has a high probability of being detected, numerous studies have evaluated the performance of two‐stage CCs . Similarly, the optimization of the detection efficiency and the spatial resolution of two‐stage CCs has been evaluated .…”

Section: Introductionmentioning

confidence: 99%

“…Because a coincidence event (i.e., the PG interacts with both the scatterer and absorber detectors) has a high probability of being detected, numerous studies have evaluated the performance of two‐stage CCs . Similarly, the optimization of the detection efficiency and the spatial resolution of two‐stage CCs has been evaluated . Hilaire et al showed that using events within an energy window of 0.5–2.5 MeV can improve the performance of a two‐stage CC.…”

Section: Introductionmentioning

confidence: 99%

“…To improve two‐stage CC performance, a previous study optimized detection efficiency and spatial resolution . The aim of this study was to further determine how well the reconstructed PG images that are obtained from various two‐stage CC configurations reproduce the distal falloff of the PG emission.…”

Section: Introductionmentioning

confidence: 99%

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Use of a LYSO‐based Compton camera for prompt gamma range verification in proton therapy

2017

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Use of a LYSO‐based Compton camera for prompt gamma range verification in proton therapy

2017

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“…As an alternative to collimated cameras, Compton cameras have also been proposed (Roellinghoff et al, 2011;Richard et al, 2012) in order to increase the counting statistic by eliminating absorbing collimating devices. The Compton camera is an electronically collimate detection system, which generally consists of a stack of scattering detectors followed by an absorbing detector (Roellinghoff et al, 2011).…”

Section: Alternatives To Pet Imaging For Treatment Delivery Verificationmentioning

confidence: 99%

Evaluation of nuclear reaction cross-sections and fragment yields in carbon beams using the SHIELD-HIT Monte Carlo code. Comparison with experiments

et al. 2012

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In light ion therapy, the knowledge of the spectra of both primary and secondary particles in the target volume is needed in order to accurately describe the treatment. The transport of ions in matter is complex and comprises both atomic and nuclear processes involving primary and secondary ions produced in the cascade of events. One of the critical issues in the simulation of ion transport is the modeling of inelastic nuclear reaction processes, in which projectile nuclei interact with target nuclei and give rise to nuclear fragments. In the Monte Carlo code SHIELD-HIT, inelastic nuclear reactions are described by the Many Stage Dynamical Model (MSDM), which includes models for the different stages of the interaction process. In this work, the capability of SHIELD-HIT to simulate the nuclear fragmentation of carbon ions in tissue-like materials was studied. The value of the parameter κ, which determines the so-called freeze-out volume in the Fermi break-up stage of the nuclear interaction process, was adjusted in order to achieve better agreement with experimental data. In this paper, results are shown both with the default value κ = 1 and the modified value κ = 10 which resulted in the best overall agreement. Comparisons with published experimental data were made in terms of total and partial charge-changing cross-sections generated by the MSDM, as well as integral and differential fragment yields simulated by SHIELD-HIT in intermediate and thick water targets irradiated with a beam of 400 MeV u(-1) (12)C ions. Better agreement with the experimental data was in general obtained with the modified parameter value (κ = 10), both on the level of partial charge-changing cross-sections and fragment yields.

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“…Bismuth germanate oxides can be used for gamma radiation [4], but the most striking application is in the medicine area, where BGO crystals are used as absorber detectors of a Compton camera for prompt γ-ray imaging during ion beam therapy [5]. In these applications, a scintillator is a streaked block of bismuth germanate oxide (BGO) providing 8 × 8 pseudo pixels and compared with materials such as LaBr 3 :Ce and LYSO:Ce detectors.…”

Section: Introductionmentioning

confidence: 99%

Sol-Gel Processing of Bismuth Germanate Thin-Films

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This study aims to obtain uniform and homogeneous bismuth germanate oxides thin films by spin coating and using the sol-gel technique with different precursors, followed by low-temperature annealing at 560 °C. By using Bi(NO3)3 precursors, we have obtained transparent, yellowish thin films with a 200 nm thickness. The structural analysis of the initial sol-gel powder has shown the presence of two crystalline structures, the cubic Bi4Ge3O12 (BGO) and monoclinic Bi2GeO5 crystallites, which evolves towards the BGO structure after annealing. The elemental analysis confirmed the composition of the desired compound Bi4Ge3O12 with 60 wt % GeO2 and 40 wt % Bi2O5. On the other hand, by changing the precursor to (Bi(CH3COO)2, the film thickness increased to 500 nm thicker due to the high viscosity of the sol, and a dominant monoclinic Bi2GeO5 crystalline structure appeared. The elemental analysis revealed a nonstoichiometric composition with 38 wt % GeO2 and 62 wt % Bi2O3. Due to the low GeO2 phase content that reacted with metastable Bi2GeO5, we obtained cubic Bi4Ge3O12 as a secondary phase, with Bi2GeO5 as a dominant crystalline phase. The redshifts of both absorptions and emissions spectra peaks confirmed a different disorder structure as an interplay between the cubic Bi4Ge3O12 (BGO) and monoclinic Bi2GeO5 phases.

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Design Study of the Absorber Detector of a Compton Camera for On-Line Control in Ion Beam Therapy

Cited by 24 publications

References 16 publications

Use of a LYSO‐based Compton camera for prompt gamma range verification in proton therapy

Use of a LYSO‐based Compton camera for prompt gamma range verification in proton therapy

Evaluation of nuclear reaction cross-sections and fragment yields in carbon beams using the SHIELD-HIT Monte Carlo code. Comparison with experiments

Sol-Gel Processing of Bismuth Germanate Thin-Films

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