Design strategies for antiviral coatings and surfaces: A review

Bregnocchi, Agnese; Jafari, Reza; Momen, Gelareh

doi:10.1016/j.apsadv.2022.100224

Cited by 20 publications

(15 citation statements)

References 119 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, due to the Covid-19 outbreak in the past two years, research on anti-viral surfaces is prosperous and well-summarized. [47][48][49][50] Although the biological structures of bacteria and viruses are different, the microorganism-killing or anti-adhesive methods are generally suitable for both bacteria and virus. Fig.…”

Section: Antimicrobial Strategies and Mechanismsmentioning

confidence: 99%

Surface antimicrobial functionalization with polymers: fabrication, mechanisms and applications

et al. 2022

View full text Add to dashboard Cite

show abstract

Section: Antimicrobial Strategies and Mechanismsmentioning

confidence: 99%

Surface antimicrobial functionalization with polymers: fabrication, mechanisms and applications

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Besides copper and its alloys, efforts are made to develop coatings for inanimate metallic and non-metallic surfaces to cover the hightouch surfaces, which are prone to soiling (accumulation of dirt, microbes, etc.). Alloys of copper, nickel, and zinc are tested against viruses to replace steel as high-touch surfaces (Bregnocchi et al, 2022). The copper alloy was shown to have a strong virucidal activity under clean and moderate soiling conditions (>four-log reduction) for virus droplets or dried virus onto the surface.…”

Section: Metals As Virucidesmentioning

confidence: 99%

Nano-antivirals: A comprehensive review

Hussain

Abro

Ahmed

et al. 2022

Front. Nanotechnol.

View full text Add to dashboard Cite

Nanoparticles can be used as inhibitory agents against various microorganisms, including bacteria, algae, archaea, fungi, and a huge class of viruses. The mechanism of action includes inhibiting the function of the cell membrane/stopping the synthesis of the cell membrane, disturbing the transduction of energy, producing toxic reactive oxygen species (ROS), and inhibiting or reducing RNA and DNA production. Various nanomaterials, including different metallic, silicon, and carbon-based nanomaterials and nanoarchitectures, have been successfully used against different viruses. Recent research strongly agrees that these nanoarchitecture-based virucidal materials (nano-antivirals) have shown activity in the solid state. Therefore, they are very useful in the development of several products, such as fabric and high-touch surfaces. This review thoroughly and critically identifies recently developed nano-antivirals and their products, nano-antiviral deposition methods on various substrates, and possible mechanisms of action. By considering the commercial viability of nano-antivirals, recommendations are made to develop scalable and sustainable nano-antiviral products with contact-killing properties.

show abstract

“…Although promising, neither of the above-mentioned strategies, used individually, offer the fast-acting and sustained antimicrobial effects that are desired for an advanced coating. Notably for passive surfaces, once pathogens are adhered, they become ineffective, resulting in the possible growth of a biofilm from only a few attached bacteria. , For the active surfaces, there is often an activation time period needed to obtain a major reduction in viral load, and as such transmission of pathogens can occur during this time. Additionally, the accumulation of dead bacteria and debris obscures the functional groups of these active surfaces, reducing their antipathogenic efficacy and resulting in a habitat for subsequent pathogen adhesion. , …”

Section: Introductionmentioning

confidence: 99%

A Bifunctional Spray Coating Reduces Contamination on Surfaces by Repelling and Killing Pathogens

Jarad

Rachwalski

Bayat

et al. 2023

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Surface-mediated transmission of pathogens is a major concern with regard to the spread of infectious diseases. Current pathogen prevention methods on surfaces rely on the use of biocides, which aggravate the emergence of antimicrobial resistance and pose harmful health effects. In response, a bifunctional and substrateindependent spray coating is presented herein. The bifunctional coating relies on wrinkled polydimethylsiloxane microparticles, decorated with biocidal gold nanoparticles to induce a "repel and kill" effect against pathogens. Pathogen repellency is provided by the structural hierarchy of the microparticles and their surface chemistry, whereas the kill mechanism is achieved using functionalized gold nanoparticles embedded on the microparticles. Bacterial tests with methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa reveal a 99.9% reduction in bacterial load on spraycoated surfaces, while antiviral tests with Phi6�a bacterial virus often used as a surrogate to SARS-CoV-2�demonstrate a 98% reduction in virus load on coated surfaces. The newly developed spray coating is versatile, easily applicable to various surfaces, and effective against various pathogens, making it suitable for reducing surface contamination in frequently touched, heavy traffic, and high-risk surfaces.

show abstract

Design strategies for antiviral coatings and surfaces: A review

Cited by 20 publications

References 119 publications

Surface antimicrobial functionalization with polymers: fabrication, mechanisms and applications

Surface antimicrobial functionalization with polymers: fabrication, mechanisms and applications

Nano-antivirals: A comprehensive review

A Bifunctional Spray Coating Reduces Contamination on Surfaces by Repelling and Killing Pathogens

Contact Info

Product

Resources

About