Design of Highly Porous Hydroxyapatite Scaffolds by Conversion of 3D Printed Gypsum Structures – A Comparison Study

Dantas, Alan Christie da Silva; Scalabrin, Debora H.; Farias, Roberta De; Barbosa, Amanda Alves; Ferraz, Andréa de Vasconcelos; Wirth, Cynthia

doi:10.1016/j.procir.2015.07.030

Cited by 14 publications

(4 citation statements)

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“…In addition, lattice structures have bio-compatibility and high strength, which can be designed into the shape of human tissue and bone to replace the diseased organs. Lattice structures have been tremendously used in the medical field because of flexible mechanical properties and structural characteristics, which can meet specific requirements [48][49][50][51][52][53][54][55][111][112][113][114][115][116][117][118][119][120]. The specific applications of lattice structures are shown in Figure 9.…”

Section: Applicationsmentioning

confidence: 99%

Design and Optimization of Lattice Structures: A Review

2020

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Cellular structures consist of foams, honeycombs, and lattices. Lattices have many outstanding properties over foams and honeycombs, such as lightweight, high strength, absorbing energy, and reducing vibration, which has been extensively studied and concerned. Because of excellent properties, lattice structures have been widely used in aviation, bio-engineering, automation, and other industrial fields. In particular, the application of additive manufacturing (AM) technology used for fabricating lattice structures has pushed the development of designing lattice structures to a new stage and made a breakthrough progress. By searching a large number of research literature, the primary work of this paper reviews the lattice structures. First, based on the introductions about lattices of literature, the definition and classification of lattice structures are concluded. Lattice structures are divided into two general categories in this paper: uniform and non-uniform. Second, the performance and application of lattice structures are introduced in detail. In addition, the fabricating methods of lattice structures, i.e., traditional processing and additive manufacturing, are evaluated. Third, for uniform lattice structures, the main concern during design is to develop highly functional unit cells, which in this paper is summarized as three different methods, i.e., geometric unit cell based, mathematical algorithm generated, and topology optimization. Forth, non-uniform lattice structures are reviewed from two aspects of gradient and topology optimization. These methods include Voronoi-tessellation, size gradient method (SGM), size matching and scaling (SMS), and homogenization, optimization, and construction (HOC). Finally, the future development of lattice structures is prospected from different aspects.

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Section: Applicationsmentioning

confidence: 99%

Design and Optimization of Lattice Structures: A Review

2020

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“…The porosity increased with the increase in the pore diameter and simultaneously the wall area shrank rapidly as shown in Table 1. Generally, with regard to the porous scaffolds, higher porosity indicates lower strength and lower elastic modulus [24,25]. However, higher porosity can promote the transportation of oxygen and nutrients and improve the metabolism system.…”

Section: Geometry Detailsmentioning

confidence: 99%

Design and Simulation of Flow Field for Bone Tissue Engineering Scaffold Based on Triply Periodic Minimal Surface

Wang

Huang

Wang

et al. 2019

Chin. J. Mech. Eng.

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A novel method was proposed to design the structure of a bone tissue engineering scaffold based on triply periodic minimal surface. In this method, reverse engineering software was used to reconstruct the surface from point cloud data. This method overcomes the limitations of commercially available software packages that prevent them from generating models with complex surfaces used for bone tissue engineering scaffolds. Additionally, the fluid field of the scaffolds was simulated through a numerical method based on finite volume and the cell proliferation performance was evaluated via an in vitro experiment. The cell proliferation and the mass flow evaluated in a bioreactor further verified the flow field simulated using computational fluid dynamics. The result of this study illustrates that the pressure value drops rapidly from 0.103 Pa to 0.011 Pa in the y-axis direction and the mass flow is unevenly distributed in the outlets. The mass flow in the side outlets is observed to be approximately 24.3 times higher than that in the bottom outlets in the range 6.13 × 10 −8 kg/s to 1.49 × 10 −6 kg/s. Moreover, the mass flow in the bottom outlets decreases from the center to the edge, whereas the mass flow in the side outlets decreases from the top to the bottom. Importantly, although the mean value of wall shear stress is significantly more than 0.05 Pa, there is still a large area with a suitable shear stress below 0.05 Pa where most cells can proliferate well. The result shows that the inlet velocity 0.0075 m/s is suitable for cell proliferation in the scaffold. This study provides an insight into the design, analysis, and in vitro experiment of a bone tissue engineering scaffold.

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“…[ 1,2 ] Lattice structure opens up the internal space and can quickly achieve multifunctional properties such as load‐bearing, impact resistance, vibration damping, and wave absorption. [ 3–5 ] The lattices have been increasingly used to replace conventional impact protection systems for mechanical energy absorption, for example, protecting objects from impacts in aerospace and automotive applications. [ 6 ] With the rapid development of additive manufacturing technology such as selective laser melting, selective laser sintering, and electron beam melting, it is possible to fabricate complex lattice structures effectively.…”

Section: Introductionmentioning

confidence: 99%

Study of Energy Absorption Characteristics and Deformation Mechanism of Stretching–Bending Synergistic Lattices Under Dynamic Compression

Yang

Liu

et al. 2022

Adv Eng Mater

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The 3D lattice structures have the characteristics of lightweight and high strength, showing good energy absorption characteristics under impact loads. Herein, stretching–bending synergistic lattices are constructed, with the macroscopic backbone in the stretching‐dominated configuration and the mesoscopic cells in the bending‐dominated configuration. The lattices organically combine the two deformation mechanisms of stretching dominant and bending dominant to exhibit high specific strength and excellent specific energy absorption. The particular deformation model and energy absorption characteristics of the stretching–bending synergistic lattices are analyzed. The dynamic compression response of the structure is found to have a unique stress climbing mechanism, which is the critical factor in enhancing its energy absorption ability. The backbone is the main part of structural energy absorption. By changing the relative density of the backbone, the yield strength and specific energy absorption of the stretching–bending synergistic lattices can be increased by more than 78% and 142%, respectively, than the uniform lattices with the same relative density. The hierarchical structure of the stretching backbone and bending cells provides a new approach for the design of impact‐resistant structures.

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Design of Highly Porous Hydroxyapatite Scaffolds by Conversion of 3D Printed Gypsum Structures – A Comparison Study

Cited by 14 publications

References 0 publications

Design and Optimization of Lattice Structures: A Review

Design and Optimization of Lattice Structures: A Review

Design and Simulation of Flow Field for Bone Tissue Engineering Scaffold Based on Triply Periodic Minimal Surface

Study of Energy Absorption Characteristics and Deformation Mechanism of Stretching–Bending Synergistic Lattices Under Dynamic Compression

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