Design of Functional Magnetic Nanocomposites for Bioseparation

Yang, Qi; Dong, Yi; Qiu, Yiwei; Yang, Xinzhou; Cao, Han; Wu, Yao

doi:10.1016/j.colsurfb.2020.111014

Cited by 38 publications

(21 citation statements)

References 174 publications

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“…The combination of Au nanoparticles and MNPs can achieve bacterial aggregation and separation to afford a more sensitive colorimetric detection effect. Due to the combination of magnetic materials, bacterial aggregation can achieve a transition from low to high concentration, thereby improving detection sensitivity [8]. For example, Mahheidari et al used thiocyanate/Au nanoparticles combined with MNPs to detect Vibrio cholerae bacteria and their toxins [41].…”

Section: Colorimetric Detectionmentioning

confidence: 99%

“…In order to overcome the shortcomings of traditional antibacterial treatment and detection methods, various metals and metal oxide nanoparticles have been used for bacterial detection and treatment [7]. MNPs have been widely used in the biological field in recent years due to their physical properties, good biocompatibility, and high binding capacity [8][9][10], including in vivo and in vitro bacterial detection and separation imaging [11], as well as the treatment of pathogenic bacteria. For example, magnetic materials were used to synthesize new structures [12] and new magnetic material composite nanoparticles with improved structural stability [13], biological activity [14], and antibacterial properties [15][16][17][18] to realize the separability and recyclability of MNPs [19][20][21].…”

Section: Introductionmentioning

confidence: 99%

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Harnessing the Intriguing Properties of Magnetic Nanoparticles to Detect and Treat Bacterial Infections

Xiang

Akakuru

et al. 2021

Magnetochemistry

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Infections caused by pathogenic bacteria, especially multidrug-resistant bacteria, have become a serious worldwide public health problem. Early diagnosis and treatment can effectively prevent the adverse effects of such infections. Therefore, there is an urgent need to develop effective methods for the early detection, prevention, and treatment of diseases that are caused by bacterial infections. So far, magnetic material nanoparticles (MNPs) have been widely used in the detection and treatment of bacterial infections as detection agents and therapeutics. Therefore, this review describes the recent research on MNPs in bacterial detection and treatment. Finally, a brief discussion of challenges and perspectives in this field is provided, which is expected to guide the further development of MNPs for bacterial detection and treatment.

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Section: Colorimetric Detectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Harnessing the Intriguing Properties of Magnetic Nanoparticles to Detect and Treat Bacterial Infections

Xiang

Akakuru

et al. 2021

Magnetochemistry

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“…Iron, cobalt, and nickel, generally under alloys (e.g., FeCo, FePt, CoPt, and FePd), oxides (e.g., Fe 3 O 4 , Fe 2 O 3 , and MnO), and ferrite nanoparticles (MnFe 2 O 4 , NiFe 2 O 4 , and ZnFe 2 O 4 ) or composites (e.g., Fe 3 O 4 –linoleic acid) have been reported for diverse applications [ 106 , 107 ], although Fe 3 O 4 and γFe 2 O 3 nanoparticles are the mostly utilized iron oxide nanoparticles because of their superparamagnetism, biocompatibility, and lower toxicity [ 108 , 109 ]. The superparamagnetic characteristic of these nanoparticles means that in the absence of an external magnetic field, they lose magnetic momentum, becoming non-magnetic, but a mean magnetic momentum appears if an external field is applied.…”

Section: Superparamagnetic Iron Oxide Nanoparticles Applicationsmentioning

confidence: 99%

Superparamagnetic Iron Oxide Nanoparticles and Essential Oils: A New Tool for Biological Applications

Miguel

Lourenço

Faleiro

2020

IJMS

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Essential oils are complex mixtures of volatile compounds with diverse biological properties. Antimicrobial activity has been attributed to the essential oils as well as their capacity to prevent pathogenic microorganisms from forming biofilms. The search of compounds or methodologies with this capacity is of great importance due to the fact that the adherence of these pathogenic microorganisms to surfaces largely contributes to antibiotic resistance. Superparamagnetic iron oxide nanoparticles have been assayed for diverse biomedical applications due to their biocompatibility and low toxicity. Several methods have been developed in order to obtain functionalized magnetite nanoparticles with adequate size, shape, size distribution, surface, and magnetic properties for medical applications. Essential oils have been evaluated as modifiers of the surface magnetite nanoparticles for improving their stabilization but particularly to prevent the growth of microorganisms. This review aims to provide an overview on the current knowledge about the use of superparamagnetic iron oxide nanoparticles and essential oils on the prevention of microbial adherence and consequent biofilm formation with the goal of being applied on the surface of medical devices. Some limitations found in the studies are discussed.

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“…The foremost advantages of IONPs are (1) their superparamagnetic behavior that enables easy handling and manipulation using an external magnetic field [ 33 ], (2) their low-cost synthesis (mainly iron salts in an alkaline environment and the chemicals for surface modification) [ 34 ] and (3) a high surface-to-volume ratio [ 35 ]. To adjust the surface properties, IONPs are coated or functionalized to avoid aggregation or biodegradation, and to enhance their selectivity for adsorption of target molecules [ 36 – 38 ]. A variety of reviews summarize different processes to prepare IONPs, from synthesis and characterization to functionalization [ 39 – 41 ].…”

Section: Introductionmentioning

confidence: 99%

Bio-nano interactions: binding proteins, polysaccharides, lipids and nucleic acids onto magnetic nanoparticles

2021

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The major interest in nanoparticles as an application platform for biotechnology arises from their high surface-to-volume ratio. Iron oxide nanoparticles (IONPs) are particularly appealing due to their superparamagnetic behavior, which enables bioseparation using external magnetic fields. In order to design advanced biomaterials, improve binding capacities and develop innovative processing solutions, a thorough understanding of the factors governing organic-inorganic binding in solution is critical but has not yet been achieved, given the wide variety of chemical and physical influences. This paper offers a critical review of experimental studies of the interactions between low cost IONPs (bare iron oxides, silica-coated or easily-functionalized surfaces) and the main groups of biomolecules: proteins, lipids, nucleic acids and carbohydrates. Special attention is devoted to the driving forces and interdependencies responsible of interactions at the solid-liquid interface, to the unique structural characteristics of each biomolecular class, and to environmental conditions influencing adsorption. Furthermore, studies focusing on mixtures, which are still rare, but absolutely necessary to understand the biocorona, are also included. This review concludes with a discussion of future work needed to fill the gaps in knowledge of bio-nano interactions, seeking to improve nanoparticles’ targeting capabilities in complex systems, and to open the door for multipurpose recognition and bioseparation processes.

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Design of Functional Magnetic Nanocomposites for Bioseparation

Cited by 38 publications

References 174 publications

Harnessing the Intriguing Properties of Magnetic Nanoparticles to Detect and Treat Bacterial Infections

Harnessing the Intriguing Properties of Magnetic Nanoparticles to Detect and Treat Bacterial Infections

Superparamagnetic Iron Oxide Nanoparticles and Essential Oils: A New Tool for Biological Applications

Bio-nano interactions: binding proteins, polysaccharides, lipids and nucleic acids onto magnetic nanoparticles

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