Design of Contact‐Active Antimicrobial Acrylate‐Based Materials Using Biocidal Macromers

Waschinski, Christian J.; Zimmermann, J.; Salz, Ulrich; Hutzler, Rolf; Sadowski, Gabriele; Tiller, Joerg C.

doi:10.1002/adma.200701095

Cited by 123 publications

(81 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…More recently, surface-attached non-releasing polymers could be realized by incorporating polymeric additives for polyurethane [76,77] as well as acrylate [78] coatings that migrate to the surface of the coating during the preparation process. This way, antimicrobial, contact-active materials can be obtained without a finishing procedure.…”

Section: Techniques Towards Surface Attached Polymersmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial Polymers in Solution and on Surfaces: Overview and Functional Principles

2012

View full text Add to dashboard Cite

Abstract:The control of microbial infections is a very important issue in modern society. In general there are two ways to stop microbes from infecting humans or deteriorating materials-disinfection and antimicrobial surfaces. The first is usually realized by disinfectants, which are a considerable environmental pollution problem and also support the development of resistant microbial strains. Antimicrobial surfaces are usually designed by impregnation of materials with biocides that are released into the surroundings whereupon microbes are killed. Antimicrobial polymers are the up and coming new class of disinfectants, which can be used even as an alternative to antibiotics in some cases. Interestingly, antimicrobial polymers can be tethered to surfaces without losing their biological activity, which enables the design of surfaces that kill microbes without releasing biocides. The present review considers the working mechanisms of antimicrobial polymers and of contact-active antimicrobial surfaces based on examples of recent research as well as on multifunctional antimicrobial materials.

show abstract

Section: Techniques Towards Surface Attached Polymersmentioning

confidence: 99%

“…Surface-grafting of biocidal polymers via self-induced migration to the surface. Created according to [78].…”

Section: Techniques Towards Surface Attached Polymersmentioning

confidence: 99%

Antimicrobial Polymers in Solution and on Surfaces: Overview and Functional Principles

2012

View full text Add to dashboard Cite

show abstract

“…First, the conventional acrylate system HEMA/GDMA was used, because we found it useful in other functional coatings already. [ 22 ] Unfortunately, the polymerized acrylate networks disintegrated completely during the initial etching step with diluted nitric acid. In order to obtain more stable acrylate networks, we varied acrylate components that provide better mechanical properties in combination with higher chemical stability.…”

Section: Doi: 101002/adma201101102mentioning

confidence: 99%

Ultrahigh‐Aspect Ratio Microfiber‐Furs as Plant‐Surface Mimics Derived from Teeth

et al. 2011

View full text Add to dashboard Cite

“…25 One such case is a class of PSM comprised of copolymers containing fluoroalkyl groups adjacent to biocidal moieties. 23,24 The fluoropolymer segments were found to migrate through the bulk polyurethane and served to "chaperone" the chloroamide or quaternary ammonium biocidal components to the surface.…”

Section: Surface Self-concentrating Amphiphilic Quaternary Ammonium Bmentioning

confidence: 99%

“…phenols and aldehydes) including: broad spectrum antimicrobial activity, effectiveness over a wide pH range, low human toxicity, low vapor pressure, amphiphilic solubility and lack of a detectable odor. Polymer surface modifiers (PSM) have recently been used to concentrate quaternary ammonium groups and other biocidal moieties at the surface-air interface, [22][23][24] driven primarily by low solubility and/or low surface energy. 25 One such case is a class of PSM comprised of copolymers containing fluoroalkyl groups adjacent to biocidal moieties.…”

Section: Surface Self-concentrating Amphiphilic Quaternary Ammonium Bmentioning

confidence: 99%

Biocides for the Battlefield - Interim Report

Wynne¹,

Fulmer²

2010

View full text Add to dashboard Cite

Report Documentation PageForm Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. The ability to disinfect surfaces and manufacture self-decontaminating surfaces has been the subject of research within the Chemistry Division of the Naval Research Laboratory. Through several previous work units, a significant synthetic undertaking was made in preparation of a variety of novel, highly mobile biocides possessing low surface energies. In addition, significant achievements in synthesis of novel classes of biocides were made, with the subsequent incorporation of these molecules into a variety of hydrogel coating systems. Further exploration of amphiphilic molecules to achieve surface modification has also been undertaken in low loading conditions. This work serves as a solid background onto which the molecules of three classes?quaternary ammonium, phenols, and pyridinium salts?are prepared and evaluated. Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. The ability to disinfect surfaces and manufacture self-decontaminating surfaces has been the subject of research within the Chemistry Division of the Naval Research Laboratory. Through several previous work units, a significant synthetic undertaking was made in preparation of a variety of novel, highly mobile biocides possessing low surface energies. In addition, significant achievements in synthesis of novel classes of biocides were made, with the subsequent incorporation of these molecules into a variety of hydrogel coating systems. Further exploration of amphiphilic molecules to achieve surface modification has also been undertaken in low loading conditions. This work serves as a solid background onto which the molecules of three classes-quaternary ammonium, phenols, and pyridinium salts-are prepared and evaluated. REPORT TYPE 1. REPORT DATE (DD-MM-YYYY) TITLE AND SUBTITLE AUTHOR(S) PERFORMING ORGANIZATION REPORT NUMBER PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) SPONSOR / MONITOR'S ACRONYM(S) 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) SPONSOR / MONITOR'S ...

show abstract

Design of Contact‐Active Antimicrobial Acrylate‐Based Materials Using Biocidal Macromers

Cited by 123 publications

References 20 publications

Antimicrobial Polymers in Solution and on Surfaces: Overview and Functional Principles

Antimicrobial Polymers in Solution and on Surfaces: Overview and Functional Principles

Ultrahigh‐Aspect Ratio Microfiber‐Furs as Plant‐Surface Mimics Derived from Teeth

Biocides for the Battlefield - Interim Report

Contact Info

Product

Resources

About