Design of an Ultrasonic Micro-Array for Near Field Sensing during Retinal Microsurgery

Clarke, Clyde; Etienne-Cummings, Ralph

doi:10.1109/iembs.2006.260840

Cited by 7 publications

(2 citation statements)

References 9 publications

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“…Because the Pro lysate contained cellular debris that interfered with cell enumeration at T0, the mean T0 cell abundance from the corresponding Ehux incubations was used for Pro incubations. Statistics were conducted in SPSS Statistics v25 (IBM) and Primer v6 (Clarke and Gorley 2006). Contour plots were produced with Ocean Data View v5.1.5 (Schlitzer 2018).…”

Section: Calculations and Statisticsmentioning

confidence: 99%

Bacterioplankton metabolism of phytoplankton lysates across a cyclone‐anticyclone eddy dipole impacts the cycling of semi‐labile organic matter in the photic zone

Wear

Carlson

Church

2020

Limnology & Oceanography

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Mesoscale eddies, prominent physical processes in the stratified ocean gyres, affect community composition and metabolic rates of both phytoplankton and heterotrophic bacterioplankton (free-living bacterial and archaeal) communities. We hypothesized that in situ differences in organic matter production would predispose bacterioplankton communities from cyclonic vs. anticyclonic eddies toward metabolic capabilities better suited to utilizing dissolved organic matter (DOM) from the phytoplankton groups commonly associated with each eddy polarity. To test this, we established dilution batch-culture bioassay incubations along a cyclone to anticyclone spatial transect in the North Pacific Subtropical Gyre. Unamended incubations, to assess spatial variability in ambient DOM bioavailability, and incubations amended with lysates of phytoplankton cultures were established and community growth and metabolic responses were assessed. Over timescales of days, lysate type was more influential than incubation origin: Prochlorococcus lysate was rapidly remineralized, while Emiliania huxleyi lysate was efficiently incorporated into biomass and developed a unique community of copiotrophic bacteria. Over timescales of 1 week to 1 month, eddy effects were indirectly apparent in their potential to promote metabolic processes related to DOM production and consumption. Surface lysate incubations showed priming of ambient DOM, that is, the remineralization of DOM, which was otherwise not bioavailable, in the presence of labile substrates. Some incubations originating from the deep chlorophyll maximum demonstrated signatures of chemoautotrophy fueled by nitrification, coincident with eddy-driven isopycnal uplift. We conclude that eddy polarity itself does not determine community-level bacterioplankton metabolic capabilities; however, mesoscale processes may indirectly affect slower, semi-labile organic matter processing in the oligotrophic ocean.

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Section: Calculations and Statisticsmentioning

confidence: 99%

Bacterioplankton metabolism of phytoplankton lysates across a cyclone‐anticyclone eddy dipole impacts the cycling of semi‐labile organic matter in the photic zone

Wear

Carlson

Church

2020

Limnology & Oceanography

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“…After updating the images based on spatial orientation at the workstation with tool overlay, the surgical impact on both the lesion and the brain can be visualized. Clarke et al proposed a 4-mm ultrasound transducer microarray for imaging and robotic guidance in retinal microsurgery [142], capable of resolving retinal structures as small as 2 µm from a distance of 100 µm. Compared to other imaging methods, the use of high-resolution OCT imaging information at the 3D location of the tool tip is potentially even more advantageous.…”

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confidence: 99%

Microsurgery Robots: Applications, Design, and Development

Wang,

Li,

et al. 2023

Sensors

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Microsurgical techniques have been widely utilized in various surgical specialties, such as ophthalmology, neurosurgery, and otolaryngology, which require intricate and precise surgical tool manipulation on a small scale. In microsurgery, operations on delicate vessels or tissues require high standards in surgeons’ skills. This exceptionally high requirement in skills leads to a steep learning curve and lengthy training before the surgeons can perform microsurgical procedures with quality outcomes. The microsurgery robot (MSR), which can improve surgeons’ operation skills through various functions, has received extensive research attention in the past three decades. There have been many review papers summarizing the research on MSR for specific surgical specialties. However, an in-depth review of the relevant technologies used in MSR systems is limited in the literature. This review details the technical challenges in microsurgery, and systematically summarizes the key technologies in MSR with a developmental perspective from the basic structural mechanism design, to the perception and human–machine interaction methods, and further to the ability in achieving a certain level of autonomy. By presenting and comparing the methods and technologies in this cutting-edge research, this paper aims to provide readers with a comprehensive understanding of the current state of MSR research and identify potential directions for future development in MSR.

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A Seasonally Dynamic Estuarine Ecosystem Provides a Diverse Prey Base for Elasmobranchs

Every

Fulton

Kyne

et al. 2018

Estuaries and Coasts

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Design of an Ultrasonic Micro-Array for Near Field Sensing during Retinal Microsurgery

Cited by 7 publications

References 9 publications

Bacterioplankton metabolism of phytoplankton lysates across a cyclone‐anticyclone eddy dipole impacts the cycling of semi‐labile organic matter in the photic zone

Bacterioplankton metabolism of phytoplankton lysates across a cyclone‐anticyclone eddy dipole impacts the cycling of semi‐labile organic matter in the photic zone

Microsurgery Robots: Applications, Design, and Development

A Seasonally Dynamic Estuarine Ecosystem Provides a Diverse Prey Base for Elasmobranchs

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