I would like to thank my advisor T. Renée Anthony for the support and guidance it took to make this thesis possible. I would also like to thank Tom Peters and Patrick O'Shaughnessy for their help with edits and evolving this work. I want to thank the organization that provided funding for this research and my education: CDC/NIOSH Education and Research Center Training Grant (T42OH008491). Finally, I would like to thank all my friends and colleagues at IREH. Thank you.