Design considerations for surface plasmon resonance based detection of human blood group in near infrared

Abstract

Surface plasmon resonance based sensor for detection of different human blood groups in near infrared region is proposed. The plasmonic structure is based on fused silica or chalcogenide sulfide glass Ge20Ga5Sb10S65, commonly known as 2S2G. Experimental results describing the wavelength-dependent refractive index variation in multiple samples of different blood groups are considered for theoretical calculations. The angular interrogation method is considered. The sensor’s performance is closely analyzed in terms of its angular shift and curve width in order to predict the design consideration for simple and accurate blood-group identifier. The results are explained in terms of light coupling and plasmon resonance condition. Chalcogenide glass-based SPR structure is able to provide highly precise detection of different blood groups. The proposed low-volume blood sensor can be very useful for simple and reliable blood sample detection in medical application.

Sensitive Detection of Dengue Virus Type 2 E-Proteins Signals Using Self-Assembled Monolayers/Reduced Graphene Oxide-PAMAM Dendrimer Thin Film-SPR Optical Sensor

“…6). The important of width (i.e., FWHM) lies in determining the resonance angle accurately 81,82 . From Table 1, it is noted that as the sputtering time for gold was fixed at 67 s with the increasing spin speed of deposition, the reflectance curve is redshifted and narrower.…”

Biomedical sensor technologies on the platform of mobile phones

“…An optical fiber SPR system can detect reactions of living cells attached to the fiber tip in a real-time manner, and human blood-group detections have been carried out by SPR with high accuracy [27,28]. Other biomedical devices like ring-shaped photodiode fabricated and mounted on a printed circuit board for pulse oximetry measurements and optical sensors used miniature LEDs for cerebral blood volume measurement are both novel and useful [29,30].…”

Analysis of Scaling Law and Figure of Merit of Fiber‐Based Biosensor

“…We shall now present the numerical results of the sensitivity function (M) defined by (13). Figures 9-12 are produced from the slopes of function of R and (L/d) (see Figure 12); (iv) M is a nonlinear increasing function of n. Figure of Merit (FOM).…”

“…The use of metal nanoparticles in biomedicine includes bioimaging, biosensing, drug delivery, and diagnostics therapeutics of cancer cell [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Surface plasmon resonances (SPRs) of various shapes of nanoparticles have been explored including shapes in sphere, rod, box, and core shell [4][5][6][7][8].…”

“…Conventional SPR sensors are difficult to be integrated in a large-scale array format. The recently developed fiberbased sensors [11][12][13][14][15][16][17] benefit is easy to fabricate and requires only a fiber-deliver of the lights and spectrometer for detection. Sensors operate in the NIR region is potentially useful for detecting low concentration of analytes functionalized nanoparticles due to its much higher refractive index sensitivity.…”