Design and test of a 64-channel charge measurement ASIC developed in CMOS 0.35μm technology

Rosa, A. La; Mazza, G.; Donetti, M.; Marchetto, F.; Luetto, L.; Attili, A.; Bourhaleb, F.; Cirio, R.; Garella, Ma; Giordanengo, S.; Givehchi, N.; Iliescu, S.; Pardo, José Manuel; Pecka, A.; Peroni, C.; Pitta, G.

doi:10.1016/j.nima.2007.09.024

Cited by 23 publications

(14 citation statements)

References 6 publications

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“…The deviations from linearity are found to be within 71%, which is considered acceptable in most of the radiotherapy applications, while for currents smaller than 5 nA, where the input current becomes comparable to the offset currents, the deviations tend to diverge. We remark that this interval corresponds to a dynamic range of $ 5 Â 10 4 , a 5-fold increase compared to a single channel as reported in [9].…”

Section: Linearitysupporting

confidence: 61%

“…It was shown [9] that this gain is fairly uniform across the channels, with a channel-to-channel variation of 1.28% rms.…”

Section: Methodsmentioning

confidence: 99%

“…It relies on splitting evenly the input current from a detector element into several readout channels and adding up all the counts of these readout channels to reconstruct the input current. We show in this paper that with such an arrangement the input current range is extended proportionally to the number of channels used, and the good linearity observed for each channel individually [9] is preserved. Furthermore, the implementation does not degrade significantly the resolution, being able to measure low currents down to hundreds of pA. As a result, by using all the 64 channels available in the TERA chip, the dynamic range can be increased by almost one order of magnitude.…”

Section: Introductionmentioning

confidence: 94%

“…The chip, named TERA, implements an architecture based on a charge-to-count converter and integrates 64 equal channels. The performances of the last version of the chip, TERA08, have been thoroughly verified and the results have been published [9]. 1 The current limit of each TERA08 channel is well above the typical currents of few hundreds of nA which are measured in present applications, but is too severe for pulsed accelerators where an instantaneous current during the pulse larger by two to three orders of magnitude is expected.…”

Section: Introductionmentioning

confidence: 99%

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A simple method to increase the current range of the TERA chip in charged particle therapy applications

Cirio

Fausti

Guarachi

et al. 2015

Nuclear Instruments and Methods in Physics Research Section A:

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a b s t r a c tThe development of the next generation of accelerators for charged particle radiotherapy aims to reduce dimensions and operational complexity of the machines by engineering pulsed beams accelerators. The drawback is the increased difficulty to monitor the beam delivery. Within each pulse, instantaneous currents larger by two to three orders of magnitude than present applications are expected, which would saturate the readout of the monitor chambers. In this paper, we report of a simple method to increase by almost two orders of magnitude the current range of an Application Specific Integrated Circuit chip previously developed by our group to read out monitor ionization chambers.

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Section: Linearitysupporting

confidence: 61%

“…It was shown [9] that this gain is fairly uniform across the channels, with a channel-to-channel variation of 1.28% rms.…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A simple method to increase the current range of the TERA chip in charged particle therapy applications

Cirio

Fausti

Guarachi

et al. 2015

Nuclear Instruments and Methods in Physics Research Section A:

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“…The size of these detectors is 24 × 24 cm 2 , to cover the maximum beam size. The detector front-end readout is based on custom designed boards, which host application specific integrated circuit (ASIC) electronics custom designed for this purpose [15,16]. The readout frequency for the integral chamber is about 1 MHz, while for the strip chambers 20 and 10 kHz respectively for x and y strips.…”

Section: Detectors For Beam Control 21 Ionization Chambersmentioning

confidence: 99%

Control Of The Dose Distribution In Charged Particle Therapy

Manganaro¹,

Attili²,

Dalmasso³

et al. 2017

Proceedings of the 26th International Nuclear Physics Conference — PoS(INPC2016)

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The use of ions in radiation therapy aims at improving the selectivity of the irradiation thanks to a favourable depth-dose profile and, in case of heavy ions, to their enhanced radiobiological effect. The treatment modality employing actively scanned pencil beams provides highly conformal dose distributions but is sensitive to uncertainties in the dose calculation, delivery and measurement. During the treatment, the delivery of the beam has to be controlled in real time and monitored with high accuracy, including any effect due to patient positioning and motion. Based on the experience gained in the collaboration with the CNAO (Centro Nazionale di Adroterapia Oncologica, Pavia, Italy), this paper is intended to give an overview of recent techniques and trends for the delivery, measurement and verification of the dose distribution in charged particle therapy with scanned ion beams, focusing in particular on real time and online techniques.

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Dose detectors, sensors, and their applications

Giordanengo

2018

Medical Physics

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This article is intended to present the different types of particle and radiation detectors available for applications in particle therapy. Several types of detectors and sensors exist for measurements of absorbed dose in reference and nonreference conditions and the ones in use for beam monitoring. Therefore, this manuscript focuses on the following applications: (a) primary methods for dosimetry in ion beams, (b) measurements of absorbed dose in realistic patient‐specific scenarios with different dose delivery configurations, and (c) beam monitoring. Water and graphite calorimeters, Faraday cups, ionization based gas detectors are described first, followed by the description of the protocols for proton and ion dosimetry. Then films, scintillator and solid‐state detectors are reviewed. Finally, several types of ionization chambers (large, pinpoint, arrays of chambers arranged in regular 1D or 2D pattern, parallel‐plate configuration with large integral electrodes or with anode segmented in strips or pixels, multi‐wire, and the multi‐gap prototype) have been considered. New beam monitors to deal with a wide range of intensity and pulsed beams expected from new accelerators, different dose fractionation and advanced delivery techniques are presented. The existing detectors available for particle therapy have been described taking into account the different requirements for devices used in reference and nonreference conditions and the ones designed for beam monitoring.

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Design and test of a 64-channel charge measurement ASIC developed in CMOS 0.35μm technology

Cited by 23 publications

References 6 publications

A simple method to increase the current range of the TERA chip in charged particle therapy applications

A simple method to increase the current range of the TERA chip in charged particle therapy applications

Control Of The Dose Distribution In Charged Particle Therapy

Dose detectors, sensors, and their applications

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