Abstract:Lishirrn Rood, Relfust R7'0 7RL, N. lrelundv U.K.Cathcpsin B is a lysosomal thiol proteinase that is thought to play an important role in the destruction of the extracellular matrix and in the invasivc process of metastatic tumour cells In this study, we have investigated the cell surface expression of a cathepsin 9-like enzyme found in association with the plasma membrane of human breast tumour cells (MDA. MB. 436). These cells were grown in serum-free medium for 48 h and washed with phosphate-buffered saline… Show more
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