Design and simulation of passive mixing in microfluidic systems with geometric variations

Jeon, Wonjin; Shin, Chee Burm

doi:10.1016/j.cej.2009.05.035

Cited by 85 publications

(50 citation statements)

References 52 publications

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“…Higher mass transfer rates are observed by shorter channel lengths for complete mixing. Comparable effects were observed for the gas-liquid slug flow [ 23 ] and single phase chaotic mixers [ 24 ]. More detailed investigations of mass transfer for liquid-liquid parallel and annular flow regimes were studied by Janovic et al [ 25 ].…”

Section: Mass Transfer Of the Regular Droplet Flowmentioning

confidence: 96%

Counter-current arrangement of microfluidic liquid-liquid droplet flow contactors

Holbach¹,

Kockmann²

2013

Green Processing and Synthesis

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Abstract:The objective of microfluidic droplet flow is the control and manipulation of fluids on the sub-mm scale. This article describes the microfluidic droplet flow in a liquid-liquid contacting unit utilizing microchannels and millichannels and their counter-current arrangement. A contacting module consists of a droplet generator, a channel to enable an intensified mass transfer between two fluids and a liquid-liquid separation device. Experiments were performed with deionized water as a continuous phase and various organic solvents as a dispersed phase. The organic droplets are generated by direct coflowing injection through a needle located in the center of the microchannel. Droplet generation and flow patterns were optically investigated in straight and winding channels. The adjacent separation unit continuously splits the organic, dispersed phase. The combined effects of gravity, wetting characteristics of the wall material and capillary forces nearly completely separate the two fluids over a wide range of flow rates. Based on the mixer-settler system, a microfluidic extraction unit is proposed that enables a multistage counter-current arrangement.

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Section: Mass Transfer Of the Regular Droplet Flowmentioning

confidence: 96%

Counter-current arrangement of microfluidic liquid-liquid droplet flow contactors

Holbach¹,

Kockmann²

2013

Green Processing and Synthesis

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“…Many studies have been carried out on channels provided with grooves [21][22][23][24], and geometries with obstructions, more similar to the profiled membranes, applied for passive micromixers [25][26][27][28][29] Moreover, several papers can be found in the literature on hydrodynamics and heat transfer predictions via Computational Fluid Dynamics (CFD) in corrugated channels, mainly with reference to heat exchangers [30][31][32][33][34], but very few woks have been devoted to mass transfer phenomena in such geometries. Zhang [35] carried out CFD modelling of fluid flow and mass transfer in a crosscorrugated triangular duct by simulating water vapour transport in dry air; correlations of friction factor and Sherwood number with the Reynolds number were proposed.…”

Section: Introduction and Literature Reviewmentioning

confidence: 99%

CFD modelling of profiled-membrane channels for reverse electrodialysis

Gurreri

Ciofalo

Cipollina

et al. 2014

Desalination and Water Treatment

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Reverse Electrodialysis (RE) is a promising technology for electric power generation from controlled mixing of two differently concentrated salt solutions, where ion exchange membranes are adopted for the generation of ionic currents within the system. Channel geometry strongly influences fluid flow and thus crucial phenomena such as pressure drop and concentration polarization. Profiled membranes are an alternative to the more commonly adopted net spacers and offer a number of advantages: avoiding the use of non-conductive and relatively expensive materials, reducing hydraulic losses and increasing the active membrane area.In this work, Computational Fluid Dynamic (CFD) simulations were performed to predict the fluid flow and mass transfer behaviour in channels with profiled membranes for RE applications. In particular, channels equipped with pillars were simulated. The influence of channel geometry on fluid flow and concentration polarization was assessed by means of a parametric analysis for different 2 profile geometries. The Unit Cell approach along with periodic boundary conditions was adopted to simulate fully developed boundary conditions. Transport equations, valid also for concentrated solutions, were obtained from the rigorous Stefan-Maxwell equation along with the assumptions of binary electrolyte and local electroneutrality. Simulation results show that in the geometries investigated here the pumping power consumption is much lower than in a conventional net spacer and very close to that of the empty channel, while calm zones are generated by the profiles, which may accentuate polarization phenomena.

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“…This includes flow during manufacturing of fibre reinforced polymer composites with liquid moulding processes (Frishfelds et al 2011;Nordlund and Lundström 2008;Tan and Pillai 2012), passive mixing in microfluidic systems (Jeon and Shin 2009) and paper making (Lundström et al 2002;Singh et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Darcy’s Law for Flow in a Periodic Thin Porous Medium Confined Between Two Parallel Plates

et al. 2016

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We study stationary incompressible fluid flow in a thin periodic porous medium. The medium under consideration is a bounded perforated 3D-domain confined between two parallel plates. The distance between the plates is δ, and the perforation consists of ε-periodically distributed solid cylinders which connect the plates in perpendicular direction. Both parameters ε, δ are assumed to be small in comparison with the planar dimensions of the plates. By constructing asymptotic expansions, three cases are analysed: (1) ε δ, (2) δ/ε ∼ constant and (3) ε δ. For each case, a permeability tensor is obtained by solving local problems. In the intermediate case, the cell problems are 3D, whereas they are 2D in the other cases, which is a considerable simplification. The dimensional reduction can be used for a wide range of ε and δ with maintained accuracy. This is illustrated by some numerical examples.

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Design and simulation of passive mixing in microfluidic systems with geometric variations

Cited by 85 publications

References 52 publications

Counter-current arrangement of microfluidic liquid-liquid droplet flow contactors

Counter-current arrangement of microfluidic liquid-liquid droplet flow contactors

CFD modelling of profiled-membrane channels for reverse electrodialysis

Darcy’s Law for Flow in a Periodic Thin Porous Medium Confined Between Two Parallel Plates

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