Design and development of pharmaceutical microprocesses in the production of nanomedicine

Méndez, Norma A. Noguez; Quirino-Barreda, Carlos Tomás; Vega, Abraham F.; Miranda-Calderón, Jorge E.; Urioste, César G.; Palomec, Xochitl C.; Martínez, Alejandro R.; Díaz, Máximo P.

doi:10.1016/b978-0-323-47720-8.00023-7

Cited by 7 publications

(1 citation statement)

References 127 publications

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“…Microparticle diameters vary in the micrometer range (typically from 1 µm to 1000 µm). Nanoparticles are considered as the end product of a wide range of chemical, physical, or magnetic interactions and biological processes leading to very small particles within the range of 1–100 nm, according to new definitions by the U.S. Food and Drug Administration [ 109 , 110 , 111 ]. The particle size and surface characteristics can be easily changed to suit the requirements for the delivery of the drugs [ 110 ].…”

Section: Micro- and Nanoparticlesmentioning

confidence: 99%

Polymeric Carriers for Delivery Systems in the Treatment of Chronic Periodontal Disease

et al. 2020

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Periodontitis (PD) is a chronic inflammatory disease of periodontal tissues caused by pathogenic microorganisms and characterized by disruption of the tooth-supporting structures. Conventional drug administration pathways in periodontal disease treatment have many drawbacks such as poor biodistribution, low selectivity of the therapeutic effect, burst release of the drug, and damage to healthy cells. To overcome this limitation, controlled drug delivery systems have been developed as a potential method to address oral infectious disease ailments. The use of drug delivery devices proves to be an excellent auxiliary method in improving the quality and effectiveness in periodontitis treatment, which includes inaccessible periodontal pockets. This review explores the current state of knowledge regarding the applications of various polymer-based delivery systems such as hydrogels, liposomes, micro-, and nanoparticles in the treatment of chronic periodontal disease. Furthermore, to present a more comprehensive understanding of the difficulties concerning the treatment of PD, a brief description of the mechanism and development of the disease is outlined.

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Section: Micro- and Nanoparticlesmentioning

confidence: 99%

Polymeric Carriers for Delivery Systems in the Treatment of Chronic Periodontal Disease

et al. 2020

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Direct Ink Writing: A 3D Printing Technology for Diverse Materials

et al. 2022

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Additive manufacturing (AM) has gained significant attention due to its ability to drive technological development as a sustainable, flexible, and customizable manufacturing scheme. Among the various AM techniques, direct ink writing (DIW) has emerged as the most versatile 3D printing technique for the broadest range of materials. DIW allows printing of practically any material, as long as the precursor ink can be engineered to demonstrate appropriate rheological behavior. This technique acts as a unique pathway to introduce design freedom, multifunctionality, and stability simultaneously into its printed structures. Here, a comprehensive review of DIW of complex 3D structures from various materials, including polymers, ceramics, glass, cement, graphene, metals, and their combinations through multimaterial printing is presented. The review begins with an overview of the fundamentals of ink rheology, followed by an in‐depth discussion of the various methods to tailor the ink for DIW of different classes of materials. Then, the diverse applications of DIW ranging from electronics to food to biomedical industries are discussed. Finally, the current challenges and limitations of this technique are highlighted, followed by its prospects as a guideline toward possible futuristic innovations.

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