Design and Characterization of a 3D-printed Staggered Herringbone Mixer

Shenoy, Vedika J; Edwards, Chelsea E. R.; Helgeson, Matthew E.; Valentine, Megan T.

doi:10.2144/btn-2021-0009

Cited by 10 publications

(7 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[17,18,30,42,43] We point out that the roughness height h is only ≃2% of the channel height H, a value that is 5-25 times lower than the roughness height in herringbone micromixers. [36,39,40]…”

Section: Design Of the Directional Microfluidic Roughnessmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…[36] The flow behavior of Newtonian fluids in slanted groove and staggered herringbone micromixers has been extensively addressed, showing that the anisotropy of groove patterns allows to engineer flow close to walls. [37][38][39][40] However, the flow of multiphase yield stress fluids in a staggered herringbone roughness has not been considered. In particular, despite extensive evidence that nonlocal fluidization is triggered by surface roughness, [17][18][19][41][42][43][44] the role of directional roughness has not been addressed so far.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Boost and Contraction of Flow by Herringbone Surface Design on the Microfluidic Channel Wall

Filippi¹,

Derzsi

Nalin

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

The handling of yield-stress fluids typically involves a jammed-to-flow transition that is pivotal for many injection and transport technologies on different scales, such as additive manufacturing, injection molding, food rheology, and oil transport. For all of these applications, it is crucial to be able to tune the fluidization under constant load. The pressure-driven flow of emulsions is reported within a microfluidic channel, one wall of which is patterned by a herringbone-riblet roughness comprising a regular array of V-shaped grooves. With respect to the pressure gradient, this pattern displays a convergent (divergent) orientation that provides a forward (backward) direction. At the tip of the herringbone pattern, the forward and backward flows are almost identical for a viscous Newtonian fluid and a diluted emulsion, whereas a surprising flow boost in the forward direction is observed as the emulsion approaches a jammed state. The flow boost is more effective at small herringbone angles and low pressure loads. 3D velocity profiles along the channel cross-section unravel unexpected heterogeneous stress, band-like distributed, with evidence of nonlocal correlations.

show abstract

Section: Design Of the Directional Microfluidic Roughnessmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Boost and Contraction of Flow by Herringbone Surface Design on the Microfluidic Channel Wall

Filippi¹,

Derzsi

Nalin

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

show abstract

“…As a key component of the microfluidic chip, the micromixer often has a great impact on the sensitivity of the microfluidic biosensor. The top or bottom of the microchannel has been shown to promote lateral flow, increase local vorticity and achieve effective mixing [ 177 , 178 ].…”

Section: Commonly Used Signal Amplification Strategies For Electroche...mentioning

confidence: 99%

Electrochemical Signal Amplification Strategies and Their Use in Olfactory and Taste Evaluation

Wang

Liu

et al. 2022

Biosensors

View full text Add to dashboard Cite

Biosensors are powerful analytical tools used to identify and detect target molecules. Electrochemical biosensors, which combine biosensing with electrochemical analysis techniques, are efficient analytical instruments that translate concentration signals into electrical signals, enabling the quantitative and qualitative analysis of target molecules. Electrochemical biosensors have been widely used in various fields of detection and analysis due to their high sensitivity, superior selectivity, quick reaction time, and inexpensive cost. However, the signal changes caused by interactions between a biological probe and a target molecule are very weak and difficult to capture directly by using detection instruments. Therefore, various signal amplification strategies have been proposed and developed to increase the accuracy and sensitivity of detection systems. This review serves as a reference for biosensor and detector research, as it introduces the research progress of electrochemical signal amplification strategies in olfactory and taste evaluation. It also discusses the latest signal amplification strategies currently being employed in electrochemical biosensors for nanomaterial development, enzyme labeling, and nucleic acid amplification techniques, and highlights the most recent work in using cell tissues as biosensitive elements.

show abstract

“…Firstly, 3D printing has advanced to the point where resolutions beyond 30 μm are possible, making it amenable to microfluidic chip fabrication. 8,9 This allows for rapid prototyping, use of highly complex structures which cannot be made with traditional layer-to-layer approaches, and faster automated fabrication than manual photolithography. Secondly, clamped microfluidic assays made from reusable and sterilizable components reduced fabrication costs and enable the use of surface treatments which are often challenging to use on permanently-bonded channel structures.…”

Section: Introductionmentioning

confidence: 99%