Design and characterisation of a thin-film electrode array with shared reference/counter electrodes for electrochemical detection

A new ratiometric electrochemical sensor for sensitive detection of bisphenol A based on poly-β-cyclodextrin/electroreduced graphene modified glassy carbon electrode

“…It is worthy to note that the electrochemical ratiometry displays a lower detection limit and wider linear range than the electrochemical method using single redox label. The detection limit of the proposed sensor is also lower than those obtained by other electrochemical methods reported previously [1,[11][12][13][14][15][16][17][18][19][20][21][22][23] (Table 1). The predominant reasons might be as follows: (1) the good characteristics of the ratiometric electrochemical assay (self-calibration, low detection limit) [43,[60][61]; (2) the synergistic effect of the electro-reduced graphene (high surface area and good electron transfer property) and Pβ-CD (lots of CD units, the excellent enrichment and host-guest recognition properties of CD).…”

“…The predominant reasons might be as follows: (1) the good characteristics of the ratiometric electrochemical assay (self-calibration, low detection limit) [43,[60][61]; (2) the synergistic effect of the electro-reduced graphene (high surface area and good electron transfer property) and Pβ-CD (lots of CD units, the excellent enrichment and host-guest recognition properties of CD). thin-film electrode array 44-4400 44 [11] Graphene/GC 80-5000 20 [12] CTAB/GC 600-100000 100 [13] peptide/Au electrode 1-5000 0.7 [14] SWCNT-CD/GC 10.8-18500 1 [15] CS/N-GS/GC 10-1300 5 [16] Gr-SP-Tyr/GC 2-5480 0.72 [17] Laccase-thionine-CB/SPCE 500-50000 200 [18] AuNPs/SGNF/GC 80-250000 35 [19] SWCNTs-COO-Poly-IL/GC 5-30000 1 [20] PGA/MWCNT-NH2/GC 100-10000 20 [21] MWCNTs/CoPc/SF/GC 50-3000 30 [22] Tyr-NiNPs/SPCE 910-48000 7.1 [23] RhB-incubated Similarly, no interference is observed for 1-naphthols, 2-naphthols, 4-aminophenol (5 equiv). These imply that the developed method has good anti-interferent ability for these inorganic ions and phenols.…”

“…Therefore, analysis and monitoring of BPA at trace level in complicated environment is very important [2,3] Various analytical methods have been reported for the detection of BPA, such as high-performance liquid chromatography [4] more sophisticated liquid chromatography-mass spectrometry [5], gas chromatography-mass spectrometry [6,7], chemiluminescence immunoassay [8], molecularly imprinted polymers technique [9], enzyme-linked immunosorbent assay [10] and electrochemical methods [1,[11][12][13][14]. Among them, electrochemical methods have advantages of simplicity, high sensitivity, good selectivity and low cost [15][16][17][18][19][20][21][22][23].…”

A multi-virus detectable microfluidic electrochemical immunosensor for simultaneous detection of H1N1, H5N1, and H7N9 virus using ZnO nanorods for sensitivity enhancement

“…Thus, thin-film electrodes containing a quasi-reference gold electrode have been considered. A thin-film three-gold electrode system was emerged as an immunosensor because of easy fabrication and integration [16]. Furthermore, a number of studies have been published to evaluate the electrochemical characteristics of microfabricated electrodes depending on various materials, sizes, and shapes [17].…”

Single Microfluidic Electrochemical Sensor System for Simultaneous Multi-Pulmonary Hypertension Biomarker Analyses

“…In addition, a microfluidic system can be integrated into a microsized substrate to control the environment for multiple electrochemical analyses. Enhancement of efficacy and detection limit is commonly used to demonstrate the performance of an integrated system Thin-film electrode arrays 14 , Au quasi-RE sensors, and other interdigitated array microelectrodes 15 have been used to improve the detection limit of enzyme-linked electrochemical assay with ease in manipulation, rapid detection, and small-sensor properties. In addition, several groups have developed microfluidic electrochemical LOC using microvalves 16, 17 .…”