This paper is concerned with the problem of actuator fault estimation (FE) for vehicle active suspension systems. First, the fast FE approach, which combines the output error term with its derivative term in the FE algorithm, is extended to the active suspension system with actuator fault and external disturbance input. Then, considering three typical kinds of actuator faults, i.e., constant gain change fault, drift fault, and stuck fault, genetic algorithm (GA) is employed to optimize the adjustable parameters in the FE algorithm, which are usually determined by trials. Finally, simulation results of FE and fault-tolerant control (FTC) are presented to illustrate the effectiveness and applicability of the proposed FE method.