“…To evaluate patients with VIS, a history, physical examination, and noninvasive testing should first be done. Then, if indicated, venous pressure measurements and descending and ascending venography [5] should be used to diagnose the condition quantitatively as suggested by the preliminary test. In addition, we are currently refining a technique to measure long-term (24-hr) ambulatory venous pressure, known as the Dynamic Leg Evaluation System (DyLES), which has been shown to be both valid and reliable [4].…”