Descending Necrotizing Mediastinitis

Descending necrotizing mediastinitis secondary to retropharyngeal abscess in a child

“…1 In our patient, a retropharyngeal abscess led to DNM. In its severe clinical form, the mortality rate of DNM remains high, despite the availability of broadspectrum antibiotics and the development of surgical and intensive care techniques.…”

“…[1][2][3][4][5] Early diagnosis is very important, and aggressive surgical drainage of the mediastinal abscess is recommended for successful treatment. [5][6][7] Although adult cases of DNM have been reported, there have been few reports of childhood cases thus far.…”

“…Descending necrotizing mediastinitis (DNM) was designated, by Estrera et al 1 in 1983, as acute mediastinitis that arises from an oropharyngeal infection. DNM is a very rare disease that is clinically important because of its high mortality rate, which ranges from 16.5% to 50% in different betamipron (PAPM/BP), at 110 mg/kg per day, and clindamycin (CLDM), at 40 mg/kg per day.…”

Chapter 2-5-2. Anaerobic infections (individual fields): anaerobic infections of the head and neck

“…Esophageal perforation can also cause this disease. Some reports have shown that approximately 70% of these cases are attributable to dental infections [5,6].…”

Akute Mediastinitis

“…Die Letalität der deszendierenden nekro tisierenden Mediastinitis ist mit 17-40% sehr hoch [13,25]. [16,26].…”