Dermoscopy in vitiligo: diagnosis and beyond

Jha, Abhijeet Kumar; Sonthalia, Sidharth; Lallas, Aimilios; Chaudhary, R K P

doi:10.1111/ijd.13795

Cited by 68 publications

(72 citation statements)

References 7 publications

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“…), the pigment spread rarely completes eluding total repigmentation of the lesion. Additional dermoscopic clues lend further credence to the predictability of these patterns . While the first pattern with the expected near‐complete repigmentation only shows tiny white dots representing eccrine openings, the post‐graft trichrome pattern displays the “tapioca sago” like appearance typified by pearly white globules (larger than the eccrine white dots and irregularly shaped) within the field that has been described by us as a dermoscopic sign of instability and progression of lesional depigmentation.…”

supporting

confidence: 62%

“…Additional dermoscopic clues lend further credence to the predictability of these patterns . While the first pattern with the expected near‐complete repigmentation only shows tiny white dots representing eccrine openings, the post‐graft trichrome pattern displays the “tapioca sago” like appearance typified by pearly white globules (larger than the eccrine white dots and irregularly shaped) within the field that has been described by us as a dermoscopic sign of instability and progression of lesional depigmentation. In conclusion, the clinicodermoscopic follow‐up results from our case series of eight vitiligo patients suggest that few months post‐micropunch grafting the trichrome color pattern with tapioca sago‐like appearance on dermoscopy should raise suspicion of lesional/disease instability, failure of surgery, and need for reinitiation of medical therapy.…”

supporting

confidence: 62%

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Post‐graft trichrome and Manchurian gravy signs on dermoscopy can predict disease activity in vitiligo lesions post‐skin grafting

Jha¹,

Sonthalia²,

Lallas

et al. 2018

Int J Dermatology

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supporting

confidence: 62%

supporting

confidence: 62%

Post‐graft trichrome and Manchurian gravy signs on dermoscopy can predict disease activity in vitiligo lesions post‐skin grafting

Jha¹,

Sonthalia²,

Lallas

et al. 2018

Int J Dermatology

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“…Perifollicular pigmentation may be found in several pigmentary diseases, but its relevance is greater in vitiligo, where it represents the first sign of repigmentation (Fig. d) …”

Section: Resultsmentioning

confidence: 99%

Standardization of dermoscopic terminology and basic dermoscopic parameters to evaluate in general dermatology (non‐neoplastic dermatoses): an expert consensus on behalf of the International Dermoscopy Society

et al. 2019

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Summary Background Over the last few years, several articles on dermoscopy of non‐neoplastic dermatoses have been published, yet there is poor consistency in the terminology among different studies. Objectives We aimed to standardize the dermoscopic terminology and identify basic parameters to evaluate in non‐neoplastic dermatoses through an expert consensus. Methods The modified Delphi method was followed, with two phases: (i) identification of a list of possible items based on a systematic literature review and (ii) selection of parameters by a panel of experts through a three‐step iterative procedure (blinded e‐mail interaction in rounds 1 and 3 and a face‐to‐face meeting in round 2). Initial panellists were recruited via e‐mail from all over the world based on their expertise on dermoscopy of non‐neoplastic dermatoses. Results Twenty‐four international experts took part in all rounds of the consensus and 13 further international participants were also involved in round 2. Five standardized basic parameters were identified: (i) vessels (including morphology and distribution); (ii) scales (including colour and distribution); (iii) follicular findings; (iv) ‘other structures’ (including colour and morphology); and (v) ‘specific clues’. For each of them, possible variables were selected, with a total of 31 different subitems reaching agreement at the end of the consensus (all of the 29 proposed initially plus two more added in the course of the consensus procedure). Conclusions This expert consensus provides a set of standardized basic dermoscopic parameters to follow when evaluating inflammatory, infiltrative and infectious dermatoses. This tool, if adopted by clinicians and researchers in this field, is likely to enhance the reproducibility and comparability of existing and future research findings and uniformly expand the universal knowledge on dermoscopy in general dermatology. What's already known about this topic? Over the last few years, several papers have been published attempting to describe the dermoscopic features of non‐neoplastic dermatoses, yet there is poor consistency in the terminology among different studies. What does this study add? The present expert consensus provides a set of standardized basic dermoscopic parameters to follow when evaluating inflammatory, infiltrative and infectious dermatoses. This consensus should enhance the reproducibility and comparability of existing and future research findings and uniformly expand the universal knowledge on dermoscopy in general dermatology.

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“…Tapioca sago (sabudana) appearance suggests the disease activity adjacent to the vitiligo lesion and emphasizes the importance of undertaking dermoscopic examination of perilesional skin in vitiligo lesions 17 …”

Section: Discussionmentioning

confidence: 99%

Combination of oral methotrexate and oral mini‐pulse dexamethasone vs either agent alone in vitiligo treatment with follow up by dermoscope

ElGhareeb

Metwalli

AbdelMoneim³

2020

Dermatologic Therapy

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This study aimed to compare the efficacy and safety of oral methotrexate (MTX) and oral mini‐pulse (OMP) dexamethasone alone and in combination in the treatment of vitiligo. A total of 42 patients with vitiligo were included in the study. The patients were treated for three months and randomly assigned into three groups including 14 patients each: group A received oral MTX, group B received OMP dexamethasone, and group C received a combination of both. Follow‐up was performed using digital photographs, Vitiligo European Task Force score, and dermoscopy. Disease extension significantly decreased in group C compared with that in groups A (P < .001) and B (P < .05). The frequency of intralesional pigmentation significantly increased (P < .05) in groups A and C and decreased (P < .05) in group B posttreatment noted using a dermoscope. Moreover, the frequency of micro‐Koebner's phenomenon and starburst pattern significantly decreased (P < .05) in groups B and C and that of tapioca sago in group C only posttreatment.

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Dermoscopy in vitiligo: diagnosis and beyond

Cited by 68 publications

References 7 publications

Post‐graft trichrome and Manchurian gravy signs on dermoscopy can predict disease activity in vitiligo lesions post‐skin grafting

Post‐graft trichrome and Manchurian gravy signs on dermoscopy can predict disease activity in vitiligo lesions post‐skin grafting

Standardization of dermoscopic terminology and basic dermoscopic parameters to evaluate in general dermatology (non‐neoplastic dermatoses): an expert consensus on behalf of the International Dermoscopy Society

Combination of oral methotrexate and oral mini‐pulse dexamethasone vs either agent alone in vitiligo treatment with follow up by dermoscope

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