Dermoscopic Features of Pigmentation in Laugier-Hunziker-Baran Syndrome

Abstract

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Pigmented fungiform lingual papillae: dermoscopic and clinical features

“…In addition, PFPT has also been reported as part of the Laugier-Hunziker syndrome, 25 characterized by pigmented macules on the lips, oral mucosa and palate, sometimes associated with melanonychia. 26 In this case, dermoscopy is a valuable tool to perform differential diagnosis: a regular brown network with a parallel furrow pattern or brown and blue grey granules 27,28 is reported in this syndrome. However, in the majority of cases, patients with PFPT do not present any associated disease.…”

Non‐melanoma Hutchinson's sign: a reappraisal of this important, remarkable melanoma simulant

“…16,17 One or more bands of longitudinal melanonychia may be present in association with a periungual pigmentation (Fig. 16,17 One or more bands of longitudinal melanonychia may be present in association with a periungual pigmentation (Fig.…”

“…Laugier syndrome Patients may display macular pigmentation of the lips, mouth and genitalia. 16,17 One or more bands of longitudinal melanonychia may be present in association with a periungual pigmentation (Fig. 6a,b).…”

Dermoscopic features in Laugier‐Hunziker syndrome

“…Tamiya et al. 7 observed numerous brownish and grey‐blue granules on a whitish‐pink area with scattered linear and dotted vasculature on the lower lip, a parallel ridge pattern on the ventral aspect of the thumb, and thin and thick greyish longitudinal lines and bands on the nail plate. In our case, we observed a regular brownish reticular pattern associated with linear and curvilinear vasculature on the labiogingival area, a brownish parallel ridge pattern on the ventral aspect of the fingers, and homogeneous brownish to greyish pigmented lines and bands with indistinct borders on the nail plate.…”

“…5 To the best of our knowledge, there have been few reports describing the dermoscopic features of pigmented lesions in patients with Laugier-Hunziker syndrome ( Table 1). [7][8][9][10] In 2002, Ronger et al 10 were the first to describe the unique patterns for differentiation from nail melanoma in 12 patients with Laugier-Hunziker syndrome, namely, thin longitudinal grey lines, homogeneous in thickness, colour and spacing, against a greyish background. However, medicationinduced melanonychia, such as that induced by minocycline, zidovudine, and hydroxyurea, or ethnictype melanonychia may have similar dermoscopic patterns.…”