Dermoscopic features in Laugier‐Hunziker syndrome

Ko, Jui‐Hung; Shih, Yi-Chin; Chiu, Chih‐Yung; Chuang, Ya‐Hui

doi:10.1111/j.1346-8138.2010.01077.x

Cited by 11 publications

(12 citation statements)

References 9 publications

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“…However, medication-induced melanonychia, such as that induced by minocycline, zidovudine, and hydroxyurea, or ethnic-type melanonychia may have similar dermoscopic patterns. [31] Simionescu et al . reported one case of mucosal melanoma on the upper lip, associated with LHS.…”

Section: Dermatoscopic Featuresmentioning

confidence: 99%

“…observed numerous brownish and gray-blue granules on a whitish-pink area with scattered linear and dotted vasculature on the lower lip, a parallel ridge pattern on the ventral aspect of the thumb, and thin and thick grayish longitudinal lines and bands on the nail plate. [31] Gencoglan et al . have reported parallel patterns on the patients’ lips and vulva.…”

Section: Dermatoscopic Featuresmentioning

confidence: 99%

“…Hence, detailed history taking and through clinical examination of a patient presenting with oral pigmentation is of paramount importance. [31]…”

Section: Differential Diagnosismentioning

confidence: 99%

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Laugier-Hunziker syndrome

Nayak¹,

Kotrashetti²,

Hosmani³

2012

J Oral Maxillofac Pathol

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Laugier–Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. They appear as macular lesions less than 5 mm in diameter. Laugier–Hunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential. Therefore, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. In India, the reported cases of this syndrome are very few. We provide a review of literature on Laugier–Hunziker syndrome with its differential diagnosis.

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Section: Dermatoscopic Featuresmentioning

confidence: 99%

Section: Dermatoscopic Featuresmentioning

confidence: 99%

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Laugier-Hunziker syndrome

Nayak¹,

Kotrashetti²,

Hosmani³

2012

J Oral Maxillofac Pathol

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“…Lentigines in LHS typically appear later in life than in those individuals with PJS 52 . Interestingly, approximately 50–60% of patients with LHS have longitudinal melanonychia, brown or black pigmentation of the nail unit 55 . In LHS there is increased pigmentation in the basal keratinocytes and increased numbers of macrophages, however, the number of melanocytes is not affected 55 .…”

Section: Laugier-hunziker Syndrome (Lhs)mentioning

confidence: 99%

The differential diagnosis of familial lentiginosis syndromes

Lodish

Stratakis

2011

Familial Cancer

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Cutaneous markers of systemic disease are vital for clinicians to recognize. This chapter outlines familial lentiginosis syndromes that include Peutz-Jeghers syndrome, Carney Complex, the PTEN hamartomatous syndromes, and LEOPARD/Noonan syndrome. The inheritance of these syndromes is autosomal dominant; they also share characteristic skin findings that offer a clue to their recognition and treatment. We will discuss the clinical presentation of these disorders, with a focus on the dermatological manifestations, and will provide an update on the molecular mechanisms involved. Recognition of cutaneous markers associated with these rare familial cancer syndromes provides the opportunity to pursue early surveillance for malignancies, as well as genetic counseling.

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“…1,2,3,4,5,6,7,8 The etiology of this disorder is still unknown. It appears that there is no a familial factor or systemic abnormality associated with the syndrome.…”

Section: Introductionmentioning

confidence: 99%

Laugier–Hunziker syndrome: a report of three cases and literature review

Wang

Duan

et al. 2012

Int J Oral Sci

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Laugier–Hunziker syndrome (LHS) is an acquired pigmentary condition affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. There is neither malignant predisposition nor underlying systemic abnormality associated with LHS. Herein, we present three uncommon cases of LHS with possibly new feature of nail pigmentation, which were diagnosed during the past 2 years. We also review the clinical and histological findings, differential diagnosis, and treatment of the syndrome in published literature.

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Dermoscopic features in Laugier‐Hunziker syndrome

Cited by 11 publications

References 9 publications

Laugier-Hunziker syndrome

Laugier-Hunziker syndrome

The differential diagnosis of familial lentiginosis syndromes

Laugier–Hunziker syndrome: a report of three cases and literature review

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