Dermatologic Radiotherapy and Thyroid Cancer

Goldschmidt, Herbert; Gorson, Robert O.; Lassen, Margit

doi:10.1001/archderm.1983.01650290023011

Cited by 15 publications

(2 citation statements)

References 28 publications

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“…Today, however, the thyroid gland is shielded by lead on all occasions. A recent paper has estimated that X-ray therapy to the hand, given in the manner described in this paper, would be associated with approximately a i in 2 million chance of inducing a carcinoma of the thyroid gland and a mortality risk of less than i in 50 million (Goldschmidt, Gorson & Lassen, 1983). Taking only a i in a million risk is the equivalent of reducing one's life expectancy by 8 minutes, or smoking 1-4 cigarettes, travelling 6 miles by canoe, 10 miles by bicycle, 300 miles by car or 1000 miles by jet aircraft (Wilson, 1979).…”

Section: Discussionmentioning

confidence: 96%

Superficial X-ray therapy in the treatment of constitutional eczema of the hands

1984

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Twenty-four patients with chronic symmetrical constitutional eczema of the hands treated with a combination of topical therapy and conventional superficial X-ray therapy. In a double-blind fashion one hand was irradiated with 100 rad (1Gy) at 50 kV on three occasions at intervals of 21 days and the other hand was given a placebo treatment. Each hand received the same topical medication, which was adjusted as necessary at each visit. The patients were seen 6, 9 and 18 weeks after X-ray therapy commenced. A significantly better therapeutic result, as assessed independently by both the patient and the observer, was recorded on the hand which had received active X-ray treatment. The advantage bestowed by active X-ray therapy was greatest 6 to 9 weeks after the start of treatment, but was still present after 18 weeks.

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Section: Discussionmentioning

confidence: 96%

Superficial X-ray therapy in the treatment of constitutional eczema of the hands

1984

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“…The most informative human data providing a quantitative relationship between radiation exposure and the delayed formation of thyroid neoplasms involve retrospective studies on subjects exposed to doses up to 1,500 rads of external radiation in childhood for a variety of benign diseases. For a period of about 30 years , x-rays were commonly used in (1) scalp irradiation for ringworm (Modan 1974, Shore 1976or later, Ron 1984; (2) neck and chest irradiation for pertussis (Webber 1975), enlarged thymus (Shore 1985), adenoids, tonsils (Crile 1975); and (3) skin irradiation for facial acne and hemangiomas (Goldschmidt 1977).…”

Section: External Radiation and Thyroid Neoplasmsmentioning

confidence: 99%