Dermatologic radiotherapy. The risk-benefit ratio

Goldschmidt, Herbert

doi:10.1001/archderm.122.12.1385

Cited by 14 publications

(10 citation statements)

References 12 publications

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“…This profile of utilization is similar to that described in the literature 3,4 . Radiotherapy is effective as primary treatment for BCC and SCC, with cure rates exceeding 90%, and generally equivalent to surgery 1,3 , 7,8 .…”

Section: Discussionsupporting

confidence: 80%

“…Radiotherapy is particularly appropriate in the head region, particularly for the nose, eyelids and ears, because it produces equivalent cure rates to surgery with a superior cosmetic outcome 3–5,7 . Radiotherapy allows a greater margin of tissue to be treated with preservation of normal tissues 3,10 , 11 .…”

Section: Discussionmentioning

confidence: 99%

“…The use of superficial radiotherapy for skin disease has generally been in decline over recent decades. Once used widely for a variety of benign and malignant skin conditions, its use diminished with the availability of alternative effective treatments for skin disease, and community fears regarding adverse effects 1–6 . The high costs of capital equipment, parts and ongoing maintenance, have also been a factor 1,2 , 5,6 .…”

Section: Introductionmentioning

confidence: 99%

“…It is recognized that in certain circumstances, radiotherapy has advantages over other treatment modalities, and may even be the treatment of choice. For example, in the treatment of certain skin carcinomas on the face, where surgery is potentially disfiguring, superficial radiotherapy can be equally effective, and offer a superior cosmetic outcome 3–5,7 …”

Section: Introductionmentioning

confidence: 99%

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Three‐year retrospective review of superficial radiotherapy for skin conditions in a Perth radiotherapy unit

Thom¹,

Heywood²,

Cassidy³

et al. 2003

Aust J Dermatology

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Western Australia has only two superficial radiotherapy units, one of which is located at Fremantle Hospital, and run by the radiation oncologists of Perth Radiation Oncology Centre. A 3-year retrospective review was undertaken of all patients who underwent treatment at this unit from 1999 to 2001. Patients were identified from the unit's log book, and data was collected from their files. For malignant skin conditions, 369 lesions were treated in 259 patients over the study period. The patients' median age was 76 years. A wide variety of conditions were treated, but the most common diagnoses were basal cell carcinoma (237 lesions) and squamous cell carcinoma (92 lesions), most commonly located in the head region. The most frequently used treatment schedule was 36 Gy in six fractions over a 3-week period. Where radiotherapy was administered as primary treatment, the diagnoses had been biopsy-proven in only 53% of cases. Fifty-four patients underwent treatment of benign skin disease over the study period; most commonly keloid scars (41 patients) followed by warts (six patients). We conclude that superficial radiotherapy has a distinct role in dermatology, particularly for skin carcinomas around the nose and eyes, which cannot presently be superseded by electron beam therapy.

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Three‐year retrospective review of superficial radiotherapy for skin conditions in a Perth radiotherapy unit

Thom¹,

Heywood²,

Cassidy³

et al. 2003

Aust J Dermatology

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“…11,12 In addition to the availability of inexpensive and effective alternative dermatologic therapies, another reason for the reduction in the use of radiation therapy for the treatment of benign skin conditions has been physician and community fears regarding therapeutic radiation's potential adverse effects. 10,[13][14][15][16][17] One of the most serious adverse effects of radiotherapy is the development of secondary skin and soft tissue neoplasms. Several studies have shown an increase in NMSCs in patients previously treated with superficial radiation for benign conditions.…”

Section: Discussionmentioning

confidence: 99%

Postradiation Sarcoma: Case Report and Review of the Potential Complications of Therapeutic Ionizing Radiation

Fangman

Cook

2006

Dermatologic Surgery

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BACKGROUND. Radiation therapy is an acceptable treatment choice for many cutaneous malignancies. A potential late sequela of ionizing radiation is the development of secondary neoplasms within the treatment field. Although there are well-known cutaneous syndromes in which the use of ionizing radiation is contraindicated, in other clinical situations, physicians may not fully realize the risks associated with this therapeutic modality.

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Late Irradiation Damage to the Skin Caused by Soft X-ray Radiation Therapy of Cutaneous Tumors

Landthaler

Hagspiel²,

Braun‐Falco³

1995

Arch Dermatol

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Dermatologic radiotherapy. The risk-benefit ratio

Cited by 14 publications

References 12 publications

Three‐year retrospective review of superficial radiotherapy for skin conditions in a Perth radiotherapy unit

Three‐year retrospective review of superficial radiotherapy for skin conditions in a Perth radiotherapy unit

Postradiation Sarcoma: Case Report and Review of the Potential Complications of Therapeutic Ionizing Radiation

Late Irradiation Damage to the Skin Caused by Soft X-ray Radiation Therapy of Cutaneous Tumors

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