Dermatofibrosarcoma Protuberans

Zina, Alberto Maria; Bundino, S

doi:10.1111/j.1600-0560.1979.tb01133.x

Cited by 27 publications

References 9 publications

(5 reference statements)

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Dermatofibrosarcoma Protuberans of the Head and Neck

Barnes¹,

Coleman²,

Johnson³

1984

Archives of Otolaryngology - Head and Neck Surgery

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\s=b\To elucidate the natural history of dermatofibrosarcoma protuberans of the head and neck, 17 cases were reviewed and compared with 92 others contained within the English literature. The prototypic case is seen as a firm, solitary, slowly enlarging, asymptomatic, cutaneous nodule between 2 and 5 cm in size and of two years' duration. It is more common in men and in persons aged between 30 and 40 years. The scalp and neck-supraclavicular fossa are the most common sites, accounting for half of the cases. Approximately 50% to 75% of the patients experience local recurrence after initial surgery and, of these, half to three fourths manifest within three years of treatment.Metastases, seen in no more than 6% of all cases, are almost invariably preceded by two or more local recurrences and occur primarily through the bloodstream to the lungs and bones and less often to regional lymph nodes. Prognostic factors, differential diagnosis, and histogenesis are included. (Arch Otolaryngol 1984;110:398-404) Dermatofi brosarcoma protuberans (DFSP) is a slowly growing, locally aggressive, rarely metastasiz¬ ing, malignant mesenchymal neo¬ plasm of the skin, which frequently recurs following attempts at exci¬ sion.

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Dermatofibrosarcoma Protuberans of the Head and Neck

Barnes¹,

Coleman²,

Johnson³

1984

Archives of Otolaryngology - Head and Neck Surgery

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Giant cell fibroblastoma. A juvenile form of dermatofibrosarcoma protuberans

Shmookler

Enzinger

Weiss

1989

Cancer

216

105

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A clinicopathologic analysis of 28 cases of giant cell fibroblastoma (GCF), a rare mesenchymal tumor occurring predominantly in the first decade of life, is presented. This disease presented as a painless, slowly enlarging, subcutaneous mass. The tumor recurred locally in 47% of the patients; however, metastasis was not detected. On microscopic examination, GCF showed an unique combination of spindle cell patterns, pleomorphic and multinucleated giant cells, myxoid areas, and distinctive sinusoid-like spaces. This unrecognized histomorphologic picture led to a misdiagnosis of sarcoma in 40% of the cases. The histogenesis of this lesion remains uncertain; however, based on both clinical and morphologic similarities, it is proposed that GCF is a juvenile form of dermatofibrosarcoma protuberans (DFSP).

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Dermatofibrosarcoma non‐protuberans: Description and report of five cases of a morpheaform variant of dermatofibrosarcoma

Abramovits

Gonzalez-Sevra

et al. 1985

Journal of Surgical Oncology

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Five cases of dermatofibrosarcoma are reported. All showed features typical of dermatofibrosarcoma protuberans except that in four cases, and a portion of the fifth case, no protusion of the tumor was noted clinically despite the rather advanced stage of growth of the tumor. These lesions resembled morphea or a morpheaform basal cell carcinoma clinically but could be recognized as "dermatofibrosarcoma non-protuberans" by physicians who had observed a previous case.

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Dermatofibrosarcoma Protuberans

Cited by 27 publications

References 9 publications

Dermatofibrosarcoma Protuberans of the Head and Neck

Dermatofibrosarcoma Protuberans of the Head and Neck

Giant cell fibroblastoma. A juvenile form of dermatofibrosarcoma protuberans

Dermatofibrosarcoma non‐protuberans: Description and report of five cases of a morpheaform variant of dermatofibrosarcoma

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