Dermal leiomyosarcoma

Kuflik, J H; Schwartz, Robert A.; Rothenberg, Jerry

doi:10.1067/mjd.2003.234

Cited by 16 publications

(8 citation statements)

References 29 publications

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“…Cutaneous LMS don't have a specific clinical presentation. The usual appearance reported is a solitary nodule, frequently with red color and ranging from 5 to 60 mm (Kuflik et al, 2003). Its surface can be smooth, ulcerated as in our case, rough, verrucous and sometimes indurated and hemorrhagic.…”

Section: Discussionmentioning

confidence: 78%

Primary cutaneous leiomyosarcoma of the flank: Case report and review

Hassouna

Saadallah

Mezghani

et al. 2015

Journal of Dermatology & Dermatologic Surgery

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Cutaneous leiomyosarcoma is a rare soft tissue sarcoma. We present a case of a 50-year-old man, with a rare location in the flank. Clinical presentation showed an ulcerative lesion. Imaging features were evocative of malignancy. Surgical excision was performed, involving oblique muscles. The diagnosis of low-grade leiomyosarcoma with free margins was made. No adjuvant therapy was indicated. Clinical and radiological follow-up of the patient during two years did not reveal recurrences. Cutaneous leiomyosarcoma of the flank is extremely rare and takes part in a group of infrequent and unknown tumors. Clinical presentation is unspecific and histological evidence is mandatory for diagnosis. Tumor extension in depth constitutes the major determinant factor for therapeutic management and prognosis. Wide surgical resection is crucial to minimize recurrence risk especially when poor prognostic factors take place. Ó 2014 Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

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Section: Discussionmentioning

confidence: 78%

Primary cutaneous leiomyosarcoma of the flank: Case report and review

Hassouna

Saadallah

Mezghani

et al. 2015

Journal of Dermatology & Dermatologic Surgery

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“…Due to their low incidence and atypical presentation, they are often misdiagnosed. The most effective treatment of CLM is wide excision with a 3-5-cm lateral margin and a depth that includes the subcutaneous tissue and fascia [3,4]. Local excision without adequate margins leads to recurrence, and increases the risk for metastatic and possibly fatal disease.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous leiomyosarcoma arising in a smallpox scar

et al. 2012

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BackgroundCutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumour that accounts for about 2–3% of all superficial soft tissue sarcomas. Although the development of various malignancies in scar tissue is well known, we report the first case of a CLM developing in a small pox scar.Case presentationA 66-year-old man presented with a painless, slow-growing lump in a small pox scar on his left shoulder. Histological biopsies showed the lesion to be a primary, well-differentiated cutaneous leiomyosarcoma. A CT scan of the thorax was conducted, which showed no signs of metastases. The complete lesion was then surgically excised, and histopathological examination revealed a radically excised cutaneous type leiomyosarcoma After 13 months’ review the patient was doing well with no evidence of tumour recurrence.ConclusionsThis is the first report of a CLM arising in a small pox scar. Although the extended time interval between scarring and malignant changes makes it difficult to advise strict follow-up for patients with small pox scars, one should be aware that atypical changes and/or symptoms occurring in a small pox scar could potentially mean malignant transformation.

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“…Atypical sites are penis, breast, orbit and the external auditory canal 6 . Clinically the lesions appear as solitary nodular cutaneous lump ranging from 0.4 to 6cm 10 . Larger size up to19 cm was reported in the literature 2 .…”

Section: Figure Ii: Lesion In Thighmentioning

confidence: 99%

“…They are of irregular contour; surface can be smooth, indurated, ulcerated, scaly, verrucous or hemorrhagic 10 .…”

Section: Figure Iii: Cutaneous Leiomyosarcoma With Marked Anaplasia (mentioning

confidence: 99%

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A Case Report On Cutaneous Leiomyosarcoma with Review of Literatures

Begum

Hossain

2018

J Curr Adv Med Res

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Cutaneous leiomyosarcoma represents superficial form of leiomyosarcoma which is a rare mesenchymal tumour originating from smooth muscle cells. Clinically cutaneous leiomyosarcoma can be confused with other cutaneous tumour and needs histopathology and immunohistochemistry to confirm the diagnosis. As it is an uncommon malignant neoplasm we encouraged reporting this case who presented to our hospital as an irregular nodular cutaneous lump of short duration in her right thigh. After local excision histopathological examination of excised specimen established the diagnosis of cutaneous leiomyosarcoma. A brief review of literature is also included here.

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Dermal leiomyosarcoma

Cited by 16 publications

References 29 publications

Primary cutaneous leiomyosarcoma of the flank: Case report and review

Primary cutaneous leiomyosarcoma of the flank: Case report and review

Cutaneous leiomyosarcoma arising in a smallpox scar

A Case Report On Cutaneous Leiomyosarcoma with Review of Literatures

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