Dermal and bronchial symptoms in children: are they caused by PAH containing parquet glue or by passive smoking?

Abstract

Informed about PAHs in parquet glue and household dust many parents demanded for total redevelopment of their flats. According to statistical evaluation of the children's symptoms, observed by their parents, no hints for an association with exposure via BaP in parquet glue or household dust were found. However, significant associations between symptoms and the exposure to environmental tobacco smoke were observed, especially bronchial and dermal symptoms. Therefore instead of redevelopment of flats with parquet glue containing coal tar, intensified information on the harmful effects of passive smoking in childhood seems to be mandatory.

Exposure to Indoor Pollutants and Wheeze and Asthma Development during Early Childhood

“…Characteristics of the studies included in the analysis are given in Table 2 . Among the relevant articles, 16 referred to prospective cohort studies [ 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ] and eight to case-control studies [ 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 ]. Five prospective cohort studies had, as a population, healthy children at risk of developing the disease (wheezing or asthma) defined either as “at least other sibling with the disease” or “maternal or paternal history of the specific disease or atopy” [ 37 , 38 , 42 , 49 , 50 ].…”

“…Five prospective cohort studies had, as a population, healthy children at risk of developing the disease (wheezing or asthma) defined either as “at least other sibling with the disease” or “maternal or paternal history of the specific disease or atopy” [ 37 , 38 , 42 , 49 , 50 ]. Ten studies were conducted in US [ 37 , 41 , 42 , 43 , 44 , 48 , 50 , 51 , 55 , 58 ], three in Sweden [ 52 , 53 , 56 ], two in Netherlands [ 36 , 38 ], two in Finland [ 47 , 54 ], two in Poland [ 45 , 46 ], one in Australia [ 57 ], one in Germany [ 40 ], one in UK [ 59 ], one in Denmark [ 49 ] and one in New Zealand [ 39 ].…”

“…Overall, among the retrieved studies exposure characterisation varied widely, particularly in terms of the exposure of interest and exposure assessment methodology. In total, 14 studies examined indoor exposure to bioaerosols [ 36 , 37 , 38 , 39 , 41 , 43 , 44 , 46 , 47 , 48 , 54 , 55 , 56 , 58 ], eight to air chemicals [ 40 , 42 , 45 , 49 , 51 , 52 , 53 , 57 ] and two assessed both bio-aerosols and specific chemicals [ 50 , 59 ]. In terms of the exposure to bioaerosols, 11 studies investigated exposure to endotoxin [ 37 , 38 , 39 , 41 , 43 , 44 , 47 , 48 , 50 , 56 , 59 ], three articles exposure to dust mites [ 36 , 46 , 59 ], three to fungi flora [ 50 , 54 , 55 ], three to glycans [ 38 , 43 , 44 ], two to EPS-Pen/Asp [ 38 , 47 ], two to LPS [ 50 , 54 ], one to pet allergens [ 36 ], one to fun...…”

Association of atopic dermatitis with smoking: A systematic review and meta-analysis

“…The association between passive smoke exposure and AD prevalence remained significant in studies from South/Central America ( Eleven studies examined stratified AD prevalence by the levels of exposure to passive smoking. [23][24][25][26][27][28][29][30][31][32][33] There were no significant associations between AD and exposure to mild (OR 1.21, 95% CI 0.81-1.80) or extensive (OR 1.08, 95% CI 0.74-1.59) amounts of passive smoking.…”

Simultaneous determination of 1- and 2-naphthol in human urine using on-line clean-up column-switching liquid chromatography–fluorescence detection

“…On the other hand the insufficient fluorescence of the naphthols-as already reported by [35]-forces one to apply sophisticated sample purification procedures to ensure specificity in this low concentration range. In the past, we already applied a tailor made pre-column (copper phthalocyanine) for the determination of three and more ring PAH metabolites [36][37][38]. Unfortunately, naphthols does not interact with this special affinity material.…”