Derivatization of several carbamate pesticides with methanesulfonyl chloride and detection by gas-liquid chromatography with the flame photometric detector: application to residues of carbaryl on lentil straw

Abstract

The mesylate derivatives of the carbamate pesticides propoxur, thien-4-yl methylcarbamate), Landrin, Carbaryl, carbofuran, 3-hydroxycarbofuran, 3-oxocarbofuran, methiocarb, methiocarb sulfoxide, and methiocarb sulfone were prepared and found to be suitable for the gas chromatographic detection of these pesticides. The carbamate pesticide is hydrolyzed with methanolic KOH, and the resultant phenol reacted with methanesulfonyl chloride and pyridine to form the mesylate derivative, which is determined by a gas chromatograph equipped with a flame photometric detector in the sulfur mode. This method is highly specific and free from interference of extracted crop materials. This procedure was applied to the determination of carbaryl residues in lentil straw. Recoveries of carbaryl from lentil straw samples fortified with the pure pesticide at the rate of 0.1 ppm averaged 103.0% (range 91.0-118.0%).

Carbaryl: A Literature Review

“…The resulting triphosphoryl derivatives were sensitive for earbaryl to approximately 0.04 ppmj 100 g sampIe. MAITLEN and McDONOUGH (1980) utilized a flame photometrie detector in the sulfur mode to determine methanesulfonyl chloride derivatives of the hydrolyzed naphthol moiety of earbaryl.…”

Gas-liquid chromatographic determination of residues of methiocarb and its toxic metabolites with the flame photometric detector after derivatization with methanesulfonyl chloride

“…In the three previously discussed procedures, the compounds are either hydrolyzed trifluoroacetylated, or silylated prior to GLC analysis. Maitlen and McDonough (1980) published a procedure for the determination of several carbamate pesticides by mesylation with methanesulfonyl chloride and then determination of the derivative by GLC with the FPD in the sulfur mode. This procedure was demonstrated on methiocarb and its sulfoxide and sulfone metabolites but was not applied to the analysis of residues in crops.…”