Der sauerstoffpartialdruck in der magenfunduswand in Abh�ngigkeit von der arteriellen Blutzufuhr

Abstract

Animal experiments in dogs were performed in order to measure oxygen tension in the gastric fundus. For this purpose an intravasal oxygen catheter electrode was inserted into the gastric submucosa. The probe recorded pO2 in an area about 2 cm in length. The oxygen tension was measured in relation to the respective blood supply of stomach. The method is suitable for determining the tendency of oxygen supply of the tissue intraoperatively as well as after implantation postoperatively. The clinical interpretation of the trend of pO2-measurements depends on further experiences.

Defining Physiological Normoxia for Improved Translation of Cell Physiology to Animal Models and Humans

“…As a result, PO 2 measurements at the submucosal aspect of the gastric fundus using micro-, 264, 265, 529) and 7.6 kPa in experimental canine models(318), with similar values (8.4 kPa) reported in canine serosa(353). Using activated charcoal as an EPR probe (see Section II-D), He and colleagues (228) determined a luminal PO 2 of 7.7 kPa at the level of the fundus/pylorus.…”

Anastomotic Tissue Oxygen Tension during Esophagectomy in Patients with Esophageal Carcinoma

“…An adequate level of tissue oxygen is the determinant of organ viability. So far tis sue oxygen tension measurement (PtC^M) from the submucosa of the stomach during esophagectomy has not been reported, except by Kunath and Uckmann [3] in dogs.…”

“…Most frequent complications of these procedures are anasto motic leakage and late stenosis of the esopha gogastrostomy [1], Although the cause of these postoperative complications is still un known, minimal blood flow and tissue hypox ia of the gastric tube are discussed as main reasons [2][3][4], After preparation of the stom ach as esophageal substitute the blood supply is derived only from the right gastroepiploic KARGER @ 1995 S. Karger AG, Basel 0014-312X/96/0281-0026S8.00/0 E-Mail karger@karger.ch F ax+ 41 61 306 12 34 artery. An adequate level of tissue oxygen is the determinant of organ viability.…”