Der Einfluss körperlicher Arbeit auf die Zahl der Thrombocyten und auf deren Haftneigung

Exercise-Induced Thrombocytosis

“…In contrast, most workers have found that short periods of brisk exercise induce a transient thrombocytosis [3,10,11]. Using a bicycle ergometer, a convenient means of reg ulating the amount of exercise performed, our results suggest that a critical amount of exercise is required to produce a detectable rise in the platelet count and that this differs between men and women.…”

“…

Most investigators have reported that brisk exercise of short duration induces a transient rise in the platelet count [3,10,11], but there is not universal agreement on this [4], The mechanism of the thrombocytosis in response to exercise is unknown. We report a study on the effect of exercise on the platelet count in healthy men and women and in asplenic subjects, and on a comparison of the platelet response to exercise before and after j?-adrenergic blockade.

Methods and Subjects

Platelet counts were performed by the method of O e tti.e and Spriggs [8] on venous blood samples anticoagulated with disodium ethylenediamine-tctraacetate (EDTA).

…”

Effect of Exercise on Blood Coagulation

“…13 It has been shown that both the concentration and adhesiveness of platelets is increased by exercise. 5 This study indicates that coagulation changes following exercise are a matter of biochemical individuality. Furthermore, it does not support the hypothesis that accelerated blood coagulation is a stress phenomena, since exercise intensities severe enough to elicit eosinopenia failed to affect blood coagulation in most subjects.…”

“…1 " 7 Coagulation time has been measured by various methods of whole blood clotting time, one-stage prothrombin time, 4 and more recently by thromboelastography. 5 In general, results have indicated that clotting is accelerated immediately after muscular exertion. However, if blood is rendered hypercoagulable by exercise, it would be expected that intravascular clotting would be more frequent among those engaged in heavy physical labor or in athletics.…”

Comparative Study of Coagulation, Fibrinolysis and Cardiorespiratory Function in Elderly and Young Subjects after Exercise*

“…Further information on the biochemical aspects of physical work has been provided during recent years by the study of blood coagulation. An increase of blood coagulability was observed in most cases after exercise—in particular, an increase of factor VIII (6, 7, 16), of factor XII (Hageman factor) (8), of platelet adhesiveness (15, 17) and of fibrinolytic activity (9, 11, 14).…”