Depressive symptoms predicting six-year mortality in depressed elderly Finns

Pulska, Tuula; Pahkala, Kimmo; Laippala, Pékka; Kivelä, Sirkka‐Liisa

doi:10.1002/1099-1166(200010)15:10<940::aid-gps220>3.0.co;2-c

Cited by 17 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Successful treatment of depression in nursing home residents results in reversal of weight loss (Morley & Kraenzle, 1995). Weight loss and anorexia were found to be important symptoms related t o increased mortality in depressed elderly (Pulska et al, 2000).…”

Section: Loss Of Motivation T O Eatmentioning

confidence: 99%

Eating Habits and Appetite Control in the Elderly: The Anorexia of Aging

Donini

Savina²,

Cannella³

2003

Int. Psychogeriatr.

294

191

View full text Add to dashboard Cite

Although a high prevalence of overweight is present in elderly people, the main concern in the elderly is the reported decline in food intake and the loss of the motivation to eat. This suggests the presence of problems associated with the regulation of energy balance and the control of food intake. A reduced energy intake causing body weight loss may be caused by social or physiological factors, or a combination of both. Poverty, loneliness, and social isolation are the predominant social factors that contribute to decreased food intake in the elderly. Depression, often associated with loss or deterioration of social networks, is a common psychological problem in the elderly and a significant cause of loss of appetite. The reduction in food intake may be due to the reduced drive to eat (hunger) resulting from a lower need state, or it arises because of more rapidly acting or more potent inhibitory (satiety) signals. The early satiation appears to be predominantly due to a decrease in adaptive relaxation of the stomach fundus resulting in early antral filling, while increased levels and effectiveness of cholecystokinin play a role in the anorexia of aging. The central feeding drive (both the opioid and the neuropeptide Y effects) appears to decline with age. Physical factors such as poor dentition and ill-fitting dentures or age-associated changes in taste and smell may influence food choice and limit the type and quantity of food eaten in older people. Common medical conditions in the elderly such as gastrointestinal disease, malabsorption syndromes, acute and chronic infections, and hypermetabolism often cause anorexia, micronutrient deficiencies, and increased energy and protein requirements. Furthermore, the elderly are major users of prescription medications, a number of which can cause malabsorption of nutrients, gastrointestinal symptoms, and loss of appetite. There is now good evidence that, although age-related reduction in energy intake is largely a physiologic effect of healthy aging, it may predispose to the harmful anorectic effects of psychological, social, and physical problems that become increasingly frequent with aging. Poor nutritional status has been implicated in the development and progression of chronic diseases commonly affecting the elderly. Protein-energy malnutrition is associated with impaired muscle function, decreased bone mass, immune dysfunction, anemia, reduced cognitive function, poor wound healing, delayed recovery from surgery, and ultimately increased morbidity and mortality. An increasing understanding of the factors that contribute to poor nutrition in the elderly should enable the development of appropriate preventive and treatment strategies and improve the health of older people.

show abstract

Section: Loss Of Motivation T O Eatmentioning

confidence: 99%

Eating Habits and Appetite Control in the Elderly: The Anorexia of Aging

Donini

Savina²,

Cannella³

2003

Int. Psychogeriatr.

294

191

View full text Add to dashboard Cite

show abstract

“…Generally, the studies published in the last decade do not support an association between the two conditions (5,(22)(23)(24)(25)(26)28,31,(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46). Penninx et al (25) suggested that chronic, severe depression predicted cancer in people older than 71 years (N ϭ 4825).…”

Section: Introductionmentioning

confidence: 99%

Occurrence of Cancer Among People With Mental Health Claims in an Insured Population

Carney

Woolson

Jones

et al. 2004

Psychosomatic Medicine

View full text Add to dashboard Cite

Insured people with mental disorder claims had an increased risk of certain malignancies and developed malignancies at younger ages. The increased odds of respiratory tumors are likely secondary to increased rates of smoking among people with mental disorders and support use of smoking cessation interventions in this population. The increased odds for brain tumors may reflect only the early presence of mental symptoms, or a true association between the two conditions. Further study of these findings is mandated.

show abstract

“…Previous research has also reported that causes of death do not differ between depressed and non‐depressed individuals. 29 Furthermore, suicide does not explain the excess mortality among depressed individuals. 29 Depression has however been shown to have an association with higher all‐cause mortality, 5 , 6 , 7 , 8 , 9 CVD mortality 6 , 8 and cancer mortality.…”

Section: Discussionmentioning

confidence: 99%

Depressive symptoms and mortality‐findings from Helsinki birth cohort study

Eriksson

Korhonen

et al. 2022

Acta Psychiatr Scand

View full text Add to dashboard Cite

Background Individuals with depression and depressive symptoms have a higher mortality rate than non‐depressed individuals. The increased comorbidity and mortality associated with depression has remained largely unexplained. The underlying pathophysiological differences between depressive subtypes, melancholic and non‐melancholic, may provide some explanation to this phenomenon. Methods One thousand nine hundred and ninety five participants (mean age 61 years) from the Helsinki Birth Cohort Study were recruited for this prospective study and followed up for a mean of 14.1 years. Information regarding medical history, lifestyle, and biochemical parameters were obtained. Depressive symptoms were assessed using the Beck Depression Inventory. Standardized mortality ratios were calculated. Results Participants were followed up for a total of 28,044 person‐years. The melancholic depressive group had an increased adjusted risk of mortality [HR 1.49 (95% CI: 1.02–2.20)] when compared to the non‐depressive group. Comparing mortality to the whole population of Finland using standardized mortality ratios (SMR) both the non‐melancholic [1.11 (95% CI: 0.85–1.44)] and melancholic depressive [1.26 (95% CI: 0.87–1.81)] groups had higher mortality than the non‐depressive group [0.82 (95% CI: 0.73–0.93)]. Conclusions Melancholic depressive symptoms are most strongly related to a higher mortality risk.

show abstract

Depressive symptoms predicting six-year mortality in depressed elderly Finns

Cited by 17 publications

References 24 publications

Eating Habits and Appetite Control in the Elderly: The Anorexia of Aging

Eating Habits and Appetite Control in the Elderly: The Anorexia of Aging

Occurrence of Cancer Among People With Mental Health Claims in an Insured Population

Depressive symptoms and mortality‐findings from Helsinki birth cohort study

Contact Info

Product

Resources

About