Depressive symptoms in stable chronic schizophrenia: prevalence and relationship to psychopathology and treatment

Baynes, D.; Mulholland, Ciaran; Cooper, Stephen; Montgomery, Renee; MacFlynn, Geraldine; Lynch, Gerard; Kelly, Carmel; King, David J.

doi:10.1016/s0920-9964(99)00205-4

Cited by 128 publications

(93 citation statements)

References 42 publications

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“…Em nosso estudo, 95% dos pacientes relataram o uso de medicação neuroléptica, dentre estes, 24% usavam medicação de depósito. Esse fato merece outras investigações uma vez que não foi coletada a informação sobre dosagem, em detrimento de dados controversos na literatura a respeito de sua associação com a depressão 48 .…”

Section: Discussionunclassified

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Depressão na esquizofrenia: prevalência e relação com a qualidade de vida

et al. 2007

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O objetivo deste estudo foi mensurar a prevalência de depressão na esquizofrenia, investigando os fatores associados e sua relação com a qualidade de vida. Foi conduzido um estudo transversal com 150 pacientes ambulatoriais, a depressão foi mensurada pela Escala Calgary de Depressão na Esquizofrenia e a qualidade de vida por meio da escala Quality of Life Scale-Brasil. Foi encontrada uma prevalência de 56% de depressão maior. Pacientes com depressão maior apresentaram pior qualidade de vida na escala global e domínio ocupacional. A qualidade de vida global foi importante para a separação dos grupos na árvore de decisão. Em pacientes com pior qualidade de vida, presença de sintomas da doença, número de medicamentos e ausência de atividades no lar se associaram à depressão, enquanto para aqueles com melhor qualidade de vida, apenas duração da doença foi importante. Esta investigação sugere alta prevalência de depressão, além de mostrar sua repercussão na qualidade de vida. Recomenda-se a investigação da depressão associada à qualidade de vida no cuidado terapêutico destes pacientes.

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Section: Discussionunclassified

“…Quando qualidade de vida 10 , incluindo pior funcionamento social, dificuldades de relacionamento e insatisfação com suporte social recebido 48 .…”

Section: Discussionunclassified

Depressão na esquizofrenia: prevalência e relação com a qualidade de vida

et al. 2007

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“…Baynes et al, 2000;Bentall et al, 2009;Kohler, Gur, Swanson, Petty, & Gur, 1998;Lindenmayer, Grochowski, & Kay, 1991;Moller & von Zerssen, 1982).…”

Section: Depression and Positive Symptomsmentioning

confidence: 99%

Cognitive factors maintaining persecutory delusions in psychosis: The contribution of depression.

Vorontsova¹,

Garety²,

Freeman³

2013

Journal of Abnormal Psychology

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Depression is common in people with schizophrenia, but how it might directly contribute to the persistence of psychotic symptoms has rarely been tested. The key aim of the present study was to test whether depression and associated cognitive processes predict the maintenance of persecutory delusions. Three groups of participants were tested at baseline: 60 patients with persecutory delusions in the context of a schizophrenia spectrum diagnosis, 30 patients with depression, and 30 nonclinical controls. They completed interviewer and self-report assessments of depression and paranoia, and measures of six cognitive factors (schematic beliefs, experiential avoidance, autobiographical memory, problem solving, rumination, worry style). The patients with persecutory delusions were then assessed again, six months later. It was found that 50% of the patients with persecutory delusions met diagnostic criteria for major depression. Cognitive processes found to be associated with depression across the groups were negative schematic beliefs about the self, experiential avoidance and rumination, but not autobiographical memory or problem solving. The severity of initial depression in patients with persecutory delusions predicted the persistence of paranoia over six months. A number of cognitive factors also predicted the persistence of persecutory delusions, including negative schematic beliefs about the self, worry, and problem-solving difficulties. In conclusion, depression is common in patients with current persecutory delusions, and it shows similar cognitive features to major depressive disorder. The results of this study indicate that depression and related processes may contribute to the maintenance of paranoia. Trials are warranted of depression-related therapeutic techniques for people with persecutory delusions.

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“…Because clients diagnosed with major depression revealed no difference in coping motives compared to those with schizophrenia, this hypothesis was also only partially confirmed. This could be explained by previous findings regarding the common cooccurrence of depression among those with schizophrenia (Baynes et al, 2000), thus potentially masking clear differences with respect to the role of depressive symptoms. The greater mood disturbances in clients with bipolar disorder (e.g., mania in addition to depression) might account for the more pronounced difference between degree of coping motives in that diagnostic group and those with schizophrenia.…”

Section: Discussionmentioning

confidence: 87%

“…Although it has long been known that depression is common in clients with schizophrenia (e.g., Baynes et al, 2000), differences in coping motives between clients with schizophrenia and bipolar disorder could be due, in part, to the inhibitory role of dissociation (i.e., blocking painful affect), mental avoidance, memory problems, difficulties in processing emotions, and self-reflective thinking (Lysaker, Davis, Lightfoot, Hunter, & Strasburger, 2005;Lysaker et al, 2011;Read, Agar, Argyle, & Aderhold, 2003). In addition, substance use has been shown to be inversely correlated with negative symptoms of schizophrenia, potentially reducing risk for socially related substance abuse and other associated high-risk behaviors (Potvin et al, 2005).…”

Section: Implications For Comorbidity Theory and Researchmentioning

confidence: 99%

Substance Use Motives in People With Severe Mental Illness: Comparisons Among Four Diagnostic Groups

O’Hare

Sherrer

2012

Journal of Social Work Practice in the Addictions

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Research has consistently shown that alcohol consumption motivated by a desire to alleviate negative emotional states predicts alcohol use and relapse among clients with cooccurring psychiatric disorders. However, studies examining the role of drinking motives in people with severe mental illness are few. This study of 283 community mental health clients (43.8% men, 55.1% women), assigned a primary Axis I diagnosis of schizophrenia (28.3%), schizoaffective (23.3%), major depression (31.1%), or bipolar I disorder (17.3%), tested the hypothesis that clients with a diagnosis of mood disorder would report greater substance use, would indicate more problems associated with substance use, and would be more likely to use substances to cope with negative emotions than would clients with schizophrenia. In addition, coping motives would account for more variance in substance use and related problems than would convivial drinking when controlling for age, gender, and Axis I diagnosis. Results largely supported these hypotheses with some exceptions. Implications for theory, research, and practice with comorbid clients are suggested.

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Depressive symptoms in stable chronic schizophrenia: prevalence and relationship to psychopathology and treatment

Cited by 128 publications

References 42 publications

Depressão na esquizofrenia: prevalência e relação com a qualidade de vida

Depressão na esquizofrenia: prevalência e relação com a qualidade de vida

Cognitive factors maintaining persecutory delusions in psychosis: The contribution of depression.

Substance Use Motives in People With Severe Mental Illness: Comparisons Among Four Diagnostic Groups

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