Depression symptoms and recurrent aphthous stomatitis—Evidence from a population‐based study in Indonesia

Abstract

Objectives This study aims to report the prevalence and distribution of recurrent aphthous stomatitis (RAS) among Indonesian adults and to test the relationship between symptom of depression and RAS. Methods Data from the 2007 Indonesia Family Life Survey (IFLS 2007) were analysed to assess the association between symptom of depression and RAS. The prevalence of RAS in the previous month was self‐reported. Symptom of depression was measured using the 10‐item Center for Epidemiologic Studies Depression (CES‐D) scale. The distribution of RAS according to age, sex and level of stress was also presented in the bivariate analysis. Multivariable logistic regression models were fitted to test associations between symptom of depression and RAS, controlling for age, sex and the stress level. Results The previous month prevalence of RAS in Indonesian population was 12%. The adjusted odds ratios (ORs) from the logistic regression models indicate that, for each unit increase in the CES‐D depression score (range: 0–30), there was a 9% increase in the odds of having RAS (OR: 1.09, 95%CI: 1.08–1.10). Being older and being male was related with lower prevalence of RAS. Conclusions A higher score of depression was related to a higher prevalence of RAS. This association was persistent even after controlling for age, sex and the level of stress.

The efficacy of herbal medicine in the treatment of recurrent aphthous stomatitis: A systematic review of randomized clinical trials

“…In this systematic review, we evaluated the therapeutic effects of medicinal plants on recurrent aphthous lesions based on the extant evidence from randomized controlled trials. Various causative factors may play role in the development of RAS, including microbial, hormonal, nutritional, immunological, and psychological factors (Belenguer‐Guallar et al, 2014; Gallo et al, 2009; Hariyani, Bramantoro, Nair, Singh, & Sengupta, 2020; Stehlikova et al, 2019), and trauma (Jurge et al, 2006) (Figure 2). Although there is no definite cause for RAS, previous studies have extensively focused on immunological factors (Akintoye & Greenberg, 2014).…”

Prevalence of recurrent aphthous stomatitis, oral submucosal fibrosis and oral leukoplakia in doctor/nurse and police officer population

“…There might be three combined factors for the increased RAS in doctor/nurse population. First, recent researches indicate the doctor and nurse as one of the population with greatest professional pressure suffers from more distress [ 26 ] and RAS is associated with psychological factors [ 2 , 3 , 6 ]. Long-term follow up study from university to career also found the RAS prevalence rate is relatively high in the doctor/nurse and dental profession [ 2 , 7 , 27 ].…”

KEJADIAN SARIAWAN PADA PEROKOK AKTIF DAN PASIF BERBASIS DATA IFLS 5 (Recurrent Aphthous Stomatitis among Active and Passive Smoker from Indonesian Family Life Survey 5)

“…Gejala depresi memiliki keterkaitan dengan prevalensi sariawan dikarenakan stress maupun depresi memicu abnormalitas mekanisme stomatognatik, sehingga menyebabkan trauma pada permukaan mukosa rongga mulut dan menimbulkan ulserasi (5) . Namun dalam sebuah penelitian yang meneliti hubungan antara kejadian sariawan dan keadaan psikologis mengungkapkan bahwa depresi dan gangguan psikologis yang lain merupakan dampak dari sariawan (19) .…”