“…It has frequently been confirmed that a rise in body temperature is associated with depression of gastric acid secretion (Meyer et al 1918;Vanzant & Snell, 1932;Bandes, Hollander & Bierman, 1948;Ghosh, 1956). Necheles, Dommers, Weiner, Olson & Rychel (1942) reported that subpyrogenic doses of pyrogens inhibited gastric motility and stated that they 170 also inhibited gastric secretion, although no data on gastric secretion were presented. Blickenstaff & Grossman (1950), however, using histamineinduced secretion in gastric pouch dogs, found no secretory inhibition by pyrogens without pyrexia.…”