Depression in mild cognitive impairment in a community sample of individuals 60–64 years old

Kumar, Rajeev; Jorm, Anthony F; Parslow, Ruth; Sachdev, Perminder S.

doi:10.1017/s1041610205003005

Cited by 43 publications

(44 citation statements)

References 7 publications

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“…This finding is congruent with the significant amount of psychiatric symptoms/syndromes reported in this disorder [2,3,[6][7][8][9][10][11]14]. However, the nature of the psychiatric diagnoses was qualitatively different in the three groups.…”

Section: Discussionsupporting

confidence: 83%

“…Similarly, minor depression was reported to be more prevalent in MCI than major depression, both in a clinical sample (26.5% vs 19.6% [11]) and in a community sample (17.2% vs 3.4% [14]), and this was the case in the present study as well (63.4% vs 22.7%). The above stands for the minor nature of the psychiatric diagnoses we found among MCI subjects.…”

Section: Discussionsupporting

confidence: 81%

“…Similarly, *Address correspondence to this author at the Margoletz Psychogeriatric Center, Ichilov Hospital, 6 Weizman Street, Tel Aviv, Israel 64239; Tel: 972-3-6973325; Fax: 972-3-6974658; E-mail: heinik@post.tau.ac.il in a sample of dementia clinic referrals Lopez et al [3] used DSM-IV criteria for major depression but provided no further specification of their diagnoses. Thus far, only Kumar et al [14] used specifically evaluated DSM-IV criteria for major and minor depressive syndromes in a small sample of community-dwelling, relatively young (60-64) subjects. Importantly, however, current nomenclature deals with disorders rather than syndromes.…”

Section: Introductionmentioning

confidence: 99%

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Psychiatric Diagnoses in a Sample of Outpatient Psycho-Geriatric New Referrals with Suspected Mild Cognitive Impairment

Heinik

Werner²,

Kavé³

2008

TOGERIMJ

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Psychiatric symptoms/syndromes are frequent in Mild Cognitive Impairment (MCI). However, only a few studies reported full psychiatric diagnoses in MCI. We describe the nosology and prevalence of psychiatric diagnoses in a group of 102 consecutive patients evaluated for suspected MCI and finally re-classified into dementia, MCI and No Cognitive Impairment. Psychiatric diagnoses were frequent in MCI and the other groups as well, however they were qualitatively different in each group.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionsupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Psychiatric Diagnoses in a Sample of Outpatient Psycho-Geriatric New Referrals with Suspected Mild Cognitive Impairment

Heinik

Werner²,

Kavé³

2008

TOGERIMJ

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“…Two studies concluded that a diagnosis of depression was associated with a greater incidence of MCI (Goveas et al, 2011;Kumar, Jorm, Parslow, & Sachdev, 2006). Taking medication for symptoms of anxiety or depression was found to be significantly predictive of a progression from not cognitively impaired to MCI over four years (Cherbuin et al, 2009).…”

Section: Temporal Relationshipmentioning

confidence: 99%

The Relationship Between Mild Cognitive Impairment and Mood in Older People

Yates¹

2018

Preprint

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Mild cognitive impairment (MCI) has received increasing attention since the early 1990s. However, considerable controversy exists over exactly how the concept of MCI is defined and measured, and the implications of assigning or receiving a diagnosis of MCI. There is evidence of a link between MCI and mood, but empirical work remains conflicted and inconclusive. The first chapter provides an overview of the MCI concept and highlights some of the issues surrounding its definition. Chapter 2 provides a detailed description of the methodology and background to the empirical work presented in Chapters 4-6. A systematic review of the literature forms the third chapter of this thesis and establishes the need for further study into the relationship between MCI and mood. Chapter 4 makes use of data from the first Cognitive Function and Ageing Study (MRC-CFAS I) to investigate the role of subjective memory complaints (SMC) in the relationship between MCI and mood over a two year period. The results indicated that SMC may be related more strongly to mood than to objective cognitive performance, which raises questions about whether SMC should be included as a criterion in the MCI definition. Chapter 5 clarifies these findings using data from a contemporary cohort in the Cognitive Function and Ageing Study Wales (CFAS Wales). Chapter 6 investigates the role of health in the relationship between MCI and mood, again using data from CFAS Wales. The findings suggest that health problems constitute a risk factor for developing depression and anxiety, which may in turn affect cognitive functioning. This presents a useful opportunity for intervention to improve the quality of life for older people by improving their physical health, or improving the management of long-term conditions. Social networks were investigated as an influential factor in the relationship between MCI and mood, using data from CFAS Wales. Whilst increases in social network size were associated with fewer mood problems and increased cognitive functioning, they did not moderate the relationship between the two. However, this finding still showed that having more social contacts is beneficial and important to the quality of life of older people. The last chapter presents a discussion of the findings in relation to each of the research questions outlined in Chapter 1. The chapter also includes a commentary on the methodological considerations that were faced when developing this thesis, the implications of the findings and directions for future research.

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“…Although many studies have reported the frequency of depressive symptoms in AD and MCI [10,11], relatively few have investigated the prevalence of depressive syndromes defined according to formal diagnostic criteria in AD [2,4,12,13,14,15,16] and MCI [17,18]. Moreover, no previous study has compared the frequency of depressive syndrome across the spectrum of the cognitive continuum, including normal aging, MCI, and AD.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Depressive Syndromes in Elderly Individuals with No Cognitive Impairment, Mild Cognitive Impairment, and Alzheimer's Disease Dementia in a Memory Clinic Setting

Lee

Byun

et al. 2016

Dement Geriatr Cogn Disord

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Aims: The aims of this study were to investigate the frequency of various depressive syndromes in elderly individuals with no cognitive impairment (NC), mild cognitive impairment (MCI), and Alzheimer's disease dementia (AD) in a memory clinic setting, and then to test whether severe and milder forms of depressive syndromes are differentially associated with the cognitive groups. Methods: For 216 NC, 478 MCI, and 316 AD subjects, we investigated the frequency of depressive syndromes, defined by three different categories: major and minor depressive disorder (MaDD and MiDD) according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, as well as depression according to the National Institute of Mental Health provisional diagnostic criteria for depression in Alzheimer's disease (NIMH-dAD). Results: The frequency of MaDD did not show any significant difference among NC, MCI, and AD. In contrast, the frequencies of MiDD and NIMH-dAD were higher than those of MaDD and showed significant group differences with a gradual increase from NC to AD. Conclusion: The findings suggest that the degenerative process of Alzheimer's disease contributes to the occurrence of mild depressive conditions, but not to severe depression.

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Depression in mild cognitive impairment in a community sample of individuals 60–64 years old

Abstract: Motivation-related depressive symptoms are more relevant in subjects with MCI than mood-related symptoms.

Cited by 43 publications

References 7 publications

Psychiatric Diagnoses in a Sample of Outpatient Psycho-Geriatric New Referrals with Suspected Mild Cognitive Impairment

Psychiatric Diagnoses in a Sample of Outpatient Psycho-Geriatric New Referrals with Suspected Mild Cognitive Impairment

The Relationship Between Mild Cognitive Impairment and Mood in Older People

Frequency of Depressive Syndromes in Elderly Individuals with No Cognitive Impairment, Mild Cognitive Impairment, and Alzheimer's Disease Dementia in a Memory Clinic Setting

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