Frequency of Depressive Syndromes in Elderly Individuals with No Cognitive Impairment, Mild Cognitive Impairment, and Alzheimer's Disease Dementia in a Memory Clinic Setting

Lee, Jun Ho; Byun, Min Soo; Yi, Dahyun; Choe, Young Min; Choi, Hyo Jung; Baek, Hong Sun; Sohn, Bo Kyung; Kim, Hyun Jung; Lee, Younghwa; Woo, Jong Inn; Lee, Dong Hoon

doi:10.1159/000449155

Cited by 9 publications

(11 citation statements)

References 43 publications

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“…Research indicates that these prevalence rates may even be higher in the oldest old who often live with multiple chronic conditions. Studies also show that cognitive impairment and dementia negatively impact dependency, institutionalization, mortality, and functional and psychological status [3,4]. In order to provide an optimal health-care provision and tailored treatment for the elderly suffering from cognitive impairment and dementia, a comprehensive assessment of their individual needs is indispensable [5].…”

Section: Introductionmentioning

confidence: 99%

Unmet Care Needs in the Oldest Old Primary Care Patients with Cognitive Disorders: Results of the AgeCoDe and AgeQualiDe Study

Stein

Pabst

Luck

et al. 2017

Dement Geriatr Cogn Disord

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Background: In the future, an increase in health care needs in the elderly is expected. Reports on unmet care needs of the oldest old with cognitive disorders are pending. This study aims at exploring unmet needs in the oldest old primary care patients with mild cognitive impairment (MCI) and dementia. Furthermore, the association between sociodemographic and clinical factors and unmet needs ought to be analyzed. Methods: Based on the study “Needs, Health Service Use, Costs and Health-Related Quality of Life in a Large Sample of Oldest-Old Primary Care Patients (85+)” (AgeQualiDe), 749 patients (unimpaired, MCI, and dementia) aged 85 years and older, their relatives (n = 421), and general practitioners (GPs) (n = 607) were assessed. Descriptive, inferential, and regression analyses were run. Results: Most unmet needs were observed in dementia patients, although needs were less frequently rated as unmet by dementia patients themselves as compared to relatives and GPs. Unmet needs were associated with MCI and dementia; other risk factors were age, education, and marital status. Conclusion: This study provides first data on unmet needs according to different perceptions in the elderly with MCI and dementia in Germany. Need assessments should be part of medical examinations to ensure a high-quality health care in the elderly.

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Section: Introductionmentioning

confidence: 99%

Unmet Care Needs in the Oldest Old Primary Care Patients with Cognitive Disorders: Results of the AgeCoDe and AgeQualiDe Study

Stein

Pabst

Luck

et al. 2017

Dement Geriatr Cogn Disord

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“…Conducting studies on this particular group is of great significance as it makes it possible to concentrate on the specific needs of persons who potentially are in the middle of the transition process from using solely informal care to a combination of both formal and informal care 1. Studies prove that there is a negative influence of cognitive impairment and dementia on the following aspects: dependency, institutionalization, mortality, as well as functional and psychological status 2. Huber et al3 lately suggested a reformulation of the definition of health formulated by the WHO, according to which the definition shall move from the current static formulation (a state of complete physical, mental, and social well-being) toward a more dynamic definition, which is based on the ability to adapt and self-manage physically, mentally, and socially, resulting in more or less physical, mental, and social health.…”

Section: Introductionmentioning

confidence: 99%

Does the Meeting Centres Support Programme reduce unmet care needs of community-dwelling older people with dementia? A controlled, 6-month follow-up Polish study

Mazurek

Szczęśniak

Lion

et al. 2019

CIA

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IntroductionIn Poland we lack a multidisciplinary and coordinated system of care for people with dementia, which would take the form of an evidence-based pathway and the number of reports on the holistic approach to caring for people living with this diagnosis is very low.Aim of the studyThe aim of the study was to investigate whether the Meeting Centres Support Programme (MCSP) is effective in meeting the needs of older people with dementia.Participants and methodsThis was done by comparing the experiences of people with dementia themselves and that of their carers at baseline and at follow-up, after 6 months of participation in MCSP or Usual Care (UC).ResultsThe study included 47 people diagnosed with mild-to-moderate dementia (n=24, MCSP group; n=23, UC control group) and 42 informal carers (n=22, MCSP group; n=20, UC control group), all living in Wroclaw in Poland and involved in the European JPND-MEETINGDEM project. To assess cognitive functioning and severity of dementia, the Mini-Mental State Examination and Global Deterioration Scale were used. The needs were assessed using the Camberwell Assessment of Need for the Elderly. The most frequently reported unmet needs at baseline both by the persons with dementia and their carers included activities of daily living, psychological distress, and the need for company. Compared to the UC group the unmet needs were reduced considerably in the MCSP group providing convincing evidence that MCSP is effective in reducing unmet needs over a 6-month period.ConclusionMCSP may be regarded as a good example of comprehensive post-diagnostic support for patients with mild-to-moderate dementia as well as their informal carers.

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“…Subclinical or subthreshold depression (SD), which is defined as the presence of relevant clinical symptoms of depression in individuals who do not meet the full criteria for a depression diagnosis, [26][27][28] is more common than MDD in elderly individuals 28 and patients with MCI. 29,30 Compared with MDD, the mechanisms of SD may be more closely associated with the degenerative processes that underlie AD. 30 Second, MCI is a heterogeneous condition with different subtypes and levels of severity and is associated with various medical factors such as vascular burden.…”

Section: Introductionmentioning

confidence: 99%

“…29,30 Compared with MDD, the mechanisms of SD may be more closely associated with the degenerative processes that underlie AD. 30 Second, MCI is a heterogeneous condition with different subtypes and levels of severity and is associated with various medical factors such as vascular burden. However, previous studies have nonetheless classified MCI into just 2 groups: aMCI and nonamnestic MCI.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Cognitive Deficit in Amnestic Mild Cognitive Impairment With Subthreshold Depression

Sun

Wang

et al. 2019

J Geriatr Psychiatry Neurol

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It is widely recognized that depression may precipitate the incidence of dementia in the elderly individuals and individuals with amnestic mild cognitive impairment (aMCI) in particular. However, the association between subthreshold depression (SD) and cognitive deficits in patients with aMCI remains unclear. To address this, we collected demographic information and conducted a battery of neuropsychological cognitive assessments in 33 aMCI participants with SD (aMCI/SD+), 33 nondepressed aMCI participants (aMCI/SD−), and 53 normal controls (NC). Both aMCI groups showed significantly poorer performance in most cognitive domains relative to the NC group (ie, memory, language, processing speed, and executive function). Notably, the aMCI/SD+ group showed significantly poorer attention/working memory compared with the aMCI/SD− group. Multiple linear regression analyses revealed a significant negative association between the severity of depressive symptoms and attention/working memory capacity (β = − .024, P = .024), accounting for 8.28% of the variations in this cognitive domain. All statistical analyses were adjusted by age, sex, and years of education. A logistic regression model had an accuracy of 72.4% in discriminating between the aMCI/SD+ and aMCI/SD− groups based on individual cognitive profiles over 6 domains. Our findings indicate that patients with aMCI with and without SD have distinct patterns of cognitive impairment. This finding may facilitate the diagnosis and treatment of SD in patients with aMCI.

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Frequency of Depressive Syndromes in Elderly Individuals with No Cognitive Impairment, Mild Cognitive Impairment, and Alzheimer's Disease Dementia in a Memory Clinic Setting

Cited by 9 publications

References 43 publications

Unmet Care Needs in the Oldest Old Primary Care Patients with Cognitive Disorders: Results of the AgeCoDe and AgeQualiDe Study

Unmet Care Needs in the Oldest Old Primary Care Patients with Cognitive Disorders: Results of the AgeCoDe and AgeQualiDe Study

Does the Meeting Centres Support Programme reduce unmet care needs of community-dwelling older people with dementia? A controlled, 6-month follow-up Polish study

Characteristics of Cognitive Deficit in Amnestic Mild Cognitive Impairment With Subthreshold Depression

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