Depression in advanced cancer – Assessment challenges and associations with disease load

Lie, Hanne C.; Hjermstad, Marianne Jensen; Fayers, Peter; Finset, Arnstein; Kaasa, Stein; Loge, Jon Håvard

doi:10.1016/j.jad.2014.11.006

Cited by 46 publications

(50 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Palliative care guidelines define the psychiatric classification systems as the clinical standard (11,14). The diagnostic algorithm might however reduce overestimation of MDE by the overlapping somatic depressive and cancer symptoms (75). The prevalence rate of MDE measured by PHQ-9 in the present study was 13.7%.…”

Section: Discussioncontrasting

confidence: 54%

The Edmonton Symptom Assessment System: Poor performance as screener for major depression in patients with incurable cancer

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 54%

The Edmonton Symptom Assessment System: Poor performance as screener for major depression in patients with incurable cancer

et al. 2016

View full text Add to dashboard Cite

show abstract

“…examined psychiatric symptoms in 969 palliative patients across Europe using the PHQ-9. They found a total rate of 45.3% for any depressive disorder [26]. This might be explained by the fact that self-report instruments generally show higher depression rates or also by the small sample size of consecutive patients within one clinic.…”

Section: Discussionmentioning

confidence: 99%

Correlation of affective temperament and psychiatric symptoms in palliative care cancer patients

Unseld

Vyssoki

Bauda

et al. 2018

Wien Klin Wochenschr

View full text Add to dashboard Cite

SummaryBackgroundPsychiatric symptoms are common in terminally ill patients. Studies linking temperamental traits and psychiatric disorders in patients suffering from advanced disease are rare. This study investigated the influence of temperament on depression and anxiety in palliative care cancer patients.MethodsA total of 53 patients at the palliative care unit (PCU) of the Medical University of Vienna were enrolled in the study. Patients filled out the TEMPS-M and the brief PHQ-9 questionnaires to examine associations between temperament, psychiatric symptoms and sociodemographic parameters.ResultsPain (67%), anorexia (58%), constipation (42%) and nausea/vomiting (40%) were the most prevalent self-reported symptoms. Self-reported symptoms of depression were less commonly reported (21.8%) than unveiled by the structured assessment by the PHQ-9 questionnaire: 26.4% (n = 14) showed mild symptoms of depression and 64.1% (n = 34) had a major depressive disorder (MDD) according to PHQ-9. The depressive and cyclothymic temperaments showed significant associations with depressive (both: p < 0.001) as well as symptoms of anxiety (p = 0.002; p = 0.036). Furthermore, the anxious temperament was significantly associated with symptoms of depression (p = 0.027).ConclusionsMood disorders are common in palliative care patients, as the majority of the patients were suffering from MDD. The depressive, cyclothymic and anxious temperaments were found to be correlated with depressive and anxious symptoms. A sensitization in this field might bring further improvements for the quality of life of palliative care patients and help to appropriately address psychiatric symptoms in palliative care.

show abstract

“…In palliative care, in particular, the need to have a clear-cut framework to assess depression has frequently been balanced with the need to focus on clinical utility and evaluation of symptoms and depressive syndromes rather than on a specific diagnosis, such as major depression [17, 18]. However, in a recent study involving 969 patients with advanced cancer within the European Palliative Care Research Collaborative-Computer Symptom Assessment Study (EPCRC-CSA) [19••], it has been shown that the prevalence of depression changed according to the scoring-methods used, specifically inclusive (algorithm scoring including the somatic symptom-criteria, rate 13.7%), exclusive (algorithm scoring excluding the somatic symptom-criteria, rate 14.9%), and sum-score (sum of all symptoms of the Patient Health Questionnaire cut-off ≥8, rate 45.3%). The scoring-method, not excluding somatic symptoms, had the greatest effect on assessment outcomes, since depression was significantly associated with pain and lower performance status.…”

Section: Diagnostic Issuesmentioning

confidence: 99%

Depressive Spectrum Disorders in Cancer: Diagnostic Issues and Intervention. A Critical Review

Caruso

GiuliaNanni

Riba

et al. 2017

Curr Psychiatry Rep

View full text Add to dashboard Cite

Depressive spectrum disorders, including major depression, persistent depression, minor and sub-syndromal depression, and other forms of depressive conditions, such as demoralization, are among the most common psychiatric consequences of cancer patients, affecting up to 60% of patients. In spite of the negative effects and the burden for cancer patients and their families, these disorders often remain under-recognized and undertreated. The present review aims at summarizing the relevant data concerning the diagnostic challenges within the depressive spectrum disorders among cancer patients. Also, the most relevant data relative to integrated intervention, including psychopharmacological and psychosocial treatment, for depression in cancer patients are critically evaluated. It is mandatory that health care professionals working in oncology (e.g., oncologists, surgeons, radiation oncologists, primary care physicians, nurses, social workers, psychologists) receive training in the diagnosis and integrated management of the different types of disorder within the spectrum of clinical depression.

show abstract

Depression in advanced cancer – Assessment challenges and associations with disease load

Cited by 46 publications

References 59 publications

The Edmonton Symptom Assessment System: Poor performance as screener for major depression in patients with incurable cancer

The Edmonton Symptom Assessment System: Poor performance as screener for major depression in patients with incurable cancer

Correlation of affective temperament and psychiatric symptoms in palliative care cancer patients

Depressive Spectrum Disorders in Cancer: Diagnostic Issues and Intervention. A Critical Review

Contact Info

Product

Resources

About