2020
DOI: 10.1017/s1041610219001716
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Depression, cognitive, and functional outcomes of Problem Adaptation Therapy (PATH) in older adults with major depression and mild cognitive deficits

Abstract: Objectives:Antidepressants have limited efficacy in older adults with depression and cognitive impairment, and psychosocial interventions for this population have been inadequately investigated. Problem Adaptation Therapy (PATH) is a psychosocial intervention for older adults with major depression, cognitive impairment, and disability.Design:This study tests the efficacy of PATH versus Supportive Therapy for Cognitively Impaired Older Adults (ST-CI) in reducing depression (Montgamery Asberg Depression Rating S… Show more

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Cited by 17 publications
(11 citation statements)
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“…Apart from the primary diagnosis of MDD, other complex needs were highlighted, such as cognitive impairment (Kanellopoulos et al . 2020), Parkinson's disease (Dobkin et al . 2018), type 2 diabetes mellitus (de Groot et al .…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Apart from the primary diagnosis of MDD, other complex needs were highlighted, such as cognitive impairment (Kanellopoulos et al . 2020), Parkinson's disease (Dobkin et al . 2018), type 2 diabetes mellitus (de Groot et al .…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, conventional antidepressant treatments demonstrated limited effectiveness in reducing depressive symptoms and disability in PMDD with cognitive impairment, underscoring the need for enhanced and tailored psychosocial CMHIs (Kanellopoulos et al . 2020). The presence of physical disability amongst PMDD with comorbid Parkinson's disease also posed as an accessibility barrier to CMHIs (Dobkin et al .…”
Section: Resultsmentioning
confidence: 99%
“…However, since depressive symptoms may interfere with motivation, lifestyle interventions may need to be paired with motivational strategies, psychotherapy, or anti-depressant medications to be effective for adults with depression. In fact, targeted treatment of depression has shown evidence of improving cognitive outcomes and overall disability [ 41 ]. These data combined with our results suggest that assessment and treatment of subclinical depression should be an integral factor in future multidomain interventions in older adults.…”
Section: Discussionmentioning
confidence: 99%
“…Compared with supportive therapy, PST was more effective in reducing disability in older clients with depression and executive dysfunction (Areán et al, 2010). Problem adaptation therapy (PATH) is an example of a home-delivered psychotherapy based on PST that involves caregiver participation, and it significantly reduced depression and improved functioning among older adults with comorbid depression, cognitive impairment, and disability (Kanellopoulos et al, 2020). IPT has been modified for use with depressed older adults with cognitive impairment and their caregivers (IPT-ci; Miller, 2009; Miller & Reynolds, 2007).…”
Section: Theory Research and Practice Of Intervention With Older Adultsmentioning
confidence: 99%