Depression and anxiety in a Portuguese MS population: Associations with physical disability and severity of disease

Silva, Ana Martins da; Vilhena, Estela; Lopes, Alneu de Andrade; Santos, Ernestina; Gonçalves, Maria José; Pinto, Cláudia; Moreira, Inês; Mendonça, Denisa; Cavaco, Sara

doi:10.1016/j.jns.2011.03.042

Cited by 65 publications

(49 citation statements)

References 46 publications

(79 reference statements)

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“…En este aspecto es preciso puntualizar que el instrumento usado por nosotros en la investigación de síntomas depresivos (cuestionario de Hamilton) no es el que predomina en la mayoría de las publicaciones sobre el tema en que se señala mayoritariamente el uso del inventario de Beck y la escala hospitalaria de depresión [30][31][32][33] . No obstante ello, nos pareció útil su uso debido a que constituye un instrumento aplicable a población ambulatoria consistente en una evaluación externa de los síntomas, que permite observar la evolutividad del cuadro y que brinda al entrevistador la posibilidad de distinguir las quejas somáticas debidas a un cuadro depresivo y las originadas por una afección médica.…”

Section: Discussionunclassified

Evaluación neuropsicológica en 129 pacientes chilenos con esclerosis múltiple recurrente remitente previo a inicio de fármacos inmunomoduladores

et al. 2012

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Section: Discussionunclassified

Evaluación neuropsicológica en 129 pacientes chilenos con esclerosis múltiple recurrente remitente previo a inicio de fármacos inmunomoduladores

et al. 2012

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“…Most psychological research in MS focuses on the high prevalence of depression 1 ; however, a small body of research suggests that anxiety disorders might be more common. [1][2][3] Unfortunately, anxiety is infrequently studied in MS, and the existing literature is challenging to synthesize owing to a variety of definitional, methodological, and assessment variations.…”

mentioning

confidence: 99%

The 7-Item Generalized Anxiety Disorder Scale as a Tool for Measuring Generalized Anxiety in Multiple Sclerosis

Terrill

Hartoonian

Beier

et al. 2015

International Journal of MS Care

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“…Katon et al [40] showed that depression was 2-3 times more frequent in chronic medical diseases. The psycho-oncology literature has shown that more than 30% of cancer patients meet the criteria for a mental condition diagnosis [58,59,60], and in chronic autoimmune diseases, psychiatric conditions and psychological distress are important associated problems [46,47,61,62,63]. Many chronic medical diseases are also associated with higher levels of mental problems [49,64].…”

Section: Discussionmentioning

confidence: 99%

Psychopathological Dimensions in Portuguese Subjects with Transthyretin Familial Amyloid Polyneuropathy

et al. 2017

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Background: Transthyretin familial amyloid polyneuropathy (TTR-FAP) is a fatal, chronic, progressive disease. It is a rare hereditary amyloidosis, which manifests as a sensorimotor neuropathy and autonomic dysfunction. It begins during adulthood. Aims and Methods: Our aim is to evaluate psychopathological dimensions in a population attending a consultation center for TTR-FAP. Two hundred and nine subjects (symptomatic and asymptomatic carriers), 84 men and 127, women participated in the study. Most subjects were married (67.1%) and most of them were still working; 33% were retired from work or on a sick leave. A sociodemographic questionnaire and The Brief Symptom Inventory (BSI) were applied. Statistical analysis was performed (descriptive analysis, Mann-Whitney, Wilcoxon, and Spearman tests). Results: The Global Symptom Index (GSI) was significantly higher in patients (p = 0.001). Considering GSI, 32.7% of total subjects were above the median for general population. When subgroups were evaluated, 25.6% of symptomatic carriers, 26.3% of subjects without established diagnosis, and 39.1% of patients were above median. GSI was significantly higher in patients (p = 0.001). Some BSI dimensions were also significantly higher in the patient group (somatization, depression, anxiety, and psychoticism) when compared with carriers. Women scored higher than men. Sick women scored higher for all dimensions except somatization. Asymptomatic carriers scored statistically higher for phobic anxiety (p = 0.01), interpersonal sensitivity, anxiety, and depression. In patients, most dimensions and GSI (rho = 0.33, p = 0.002) had positive correlations with years of disease. Conclusions: TTR-FAP patients and carriers are a very vulnerable group for psychological distress and psychopathological problems. Women and patients are at higher risk.

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Depression and anxiety in a Portuguese MS population: Associations with physical disability and severity of disease

Cited by 65 publications

References 46 publications

Evaluación neuropsicológica en 129 pacientes chilenos con esclerosis múltiple recurrente remitente previo a inicio de fármacos inmunomoduladores

Evaluación neuropsicológica en 129 pacientes chilenos con esclerosis múltiple recurrente remitente previo a inicio de fármacos inmunomoduladores

The 7-Item Generalized Anxiety Disorder Scale as a Tool for Measuring Generalized Anxiety in Multiple Sclerosis

Psychopathological Dimensions in Portuguese Subjects with Transthyretin Familial Amyloid Polyneuropathy

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