Dentinal Tubule Occlusion with Lanthanum Fluoride and Powdered Apatite Glass Ceramics in vitro .

Mukai, Yukinori; Tomiyama, Kiyoshi; Okada, Shusaku; Mukai, Katsumi; Negishi, Hideyuki; Fujihara, Tsutomu; Teranaka, Toshio

doi:10.4012/dmj.17.253

Cited by 9 publications

(12 citation statements)

References 24 publications

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“…Depth of mineral deposition in this in vivo study was 30 µm. This is in accordance with data from in vitro studies (range, 20-30 µm depth) (Mukai et al, 1998;Massara et al, 2002;Kitasako et al, 2003;Exterkate et al, 2005). In our in vivo study, after a period of 3 mos, mineral levels were similar at interface and 100 µm into dentin.…”

Section: Discussionsupporting

confidence: 95%

In vivo Dentin Remineralization by Calcium-phosphate Cement

et al. 2010

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Minimally invasive caries-removal procedures remove only caries-infected dentin and preserve caries-affected dentin that becomes remineralized. Dental cements containing calcium phosphate promote remineralization. This study evaluated the in vivo remineralization capacity of resin-based calcium-phosphate cement (Ca-P) used for indirect pulp-capping. Carious and sound teeth indicated for extraction were randomly restored with the Ca-P base or without base (control), followed by adhesive restoration. Study teeth were extracted after three months, followed by elemental analysis of the cavity floor. Mineral content of affected or sound dentin at the cavity floor was quantified by electron probe micro-analysis to 100-mum depth. After three months, caries-affected dentin underneath the Ca-P base showed significantly increased calcium and phosphorus content to a depth of 30 mum. Mineral content of treated caries-affected dentin was in the range of healthy dentin, revealing the capacity of Ca-P base to promote remineralization of caries-affected dentin.

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Section: Discussionsupporting

confidence: 95%

In vivo Dentin Remineralization by Calcium-phosphate Cement

et al. 2010

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“…There were eight studies which were excluded because they were in vitro investigations and did not meet the inclusion criteria [51–58]. Another study was excluded since the HAP was used as an in-office agent rather than a toothpaste [59] whereas Orsini et al's [60] study was excluded due to the lack of a negative control being used.…”

Section: Resultsmentioning

confidence: 99%

“…There were eight nano-HAP studies which were excluded because they were in vitro investigations (effect on dentine tubule occlusion) and therefore did not meet the inclusion criteria [51–58] (Table 3). Two randomized controlled trials [51, 52] investigating the effects of nano-HAP on DH were also retrieved and subsequently excluded from the present review due to the fact that (1) the desensitizing agents were applied in office and as a dry sol gel or liquid precipitate form and not as a OTC dentifrice or toothpaste [59] and due to (2) the lack of a negative control respectively [60].…”

Section: Discussionmentioning

confidence: 99%

The Efficacy of Selected Desensitizing OTC Products: A Systematic Review

2014

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Objectives. The aim of the present study was to review the published literature in order to identify relevant studies for inclusion and to determine whether there was any evidence on the clinical effectiveness of selected desensitizing toothpastes, calcium sodium phosphosilicate (CSPS), amorphous calcium phosphate (ACP), nanohydroxyapatite, and casein phosphopeptide-amorphous calcium phosphate (tooth mousse) on reducing dentine hypersensitivity (DH). Materials and Methods. Following a review of 593 papers identified from searching both electronic databases (PUBMED) and hand searching of relevant written journals, only 5 papers were accepted for inclusion. Results. Analysis of the included studies (3 CSPS and 2 ACP) would suggest that there may be some benefit for patients using these products for reducing DH. No direct comparative studies were available to assess all these products under the same conditions neither were there any comparative randomised controlled studies that compared at least two of these products in determining their effectiveness in treating DH. Conclusions. Due to the small number of included studies, there are limited clinical data to support any claims of clinical efficacy of these OTC products. Further studies are therefore required to determine the efficacy of these products in well-controlled RCT studies with a larger sample size.

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“…Minimally invasive treatments, such as ultraconserva tive caries removal (MertzFairhurst et al, 1998;Maltz et al, 2002), atrau matic restorative techniques (Frencken et al, 1994), and indirect pulpcapping procedures (Bjørndal et al, 1997), have shown that caries can be halted, and affect tissue remineralization. Remineralization of residual affected dentin can be promoted by the use of bioactive, ionreleasing base materials, e.g., glassionomer or resinbased calciumphosphate cements (RCPC) (Mukai et al, 1998;Dickens et al, 2003Dickens et al, , 2004Exterkate et al, 2005;Ngo et al, 2006). In vitro remineralization experiments with RCPC resulted in significantly increased mineral content, documenting the capacity of RCPC to remineralize and promote healing of mineraldeficient dentin (Dickens et al, 2003;Dickens and Flaim, 2008).…”

Section: Introductionmentioning

confidence: 99%

In vivo Dentin Microhardness beneath a Calcium-Phosphate Cement

et al. 2010

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A minimally invasive caries-removal technique preserves potentially repairable, caries-affected dentin. Mineral-releasing cements may promote remineralization of soft residual dentin. This study evaluated the in vivo remineralization capacity of resin-based calcium-phosphate cement (Ca-PO4) used for indirect pulp-capping. Permanent carious and sound teeth indicated for extraction were excavated and restored either with or without the Ca-PO4 base (control), followed by adhesive restoration. Study teeth were extracted after 3 months, followed by sectioning and in vitro microhardness analysis of the cavity floor to 115-µm depth. Caries-affected dentin that received acid conditioning prior to Ca-PO4 basing showed significantly increased Knoop hardness near the cavity floor. The non-etched group presented results similar to those of the non-treated group. Acid etching prior to cement application increased microhardness of residual dentin near the interface after 3 months in situ.

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Dentinal Tubule Occlusion with Lanthanum Fluoride and Powdered Apatite Glass Ceramics in vitro .

Abstract: the dentinal tubules. These results suggest that the reaction products produced by sequential treatment with acidic fluoride and LaCl3 and powdered apatite glass ceramics are able to effectively occlude dentinal tubules.

Cited by 9 publications

References 24 publications

In vivo Dentin Remineralization by Calcium-phosphate Cement

In vivo Dentin Remineralization by Calcium-phosphate Cement

The Efficacy of Selected Desensitizing OTC Products: A Systematic Review

In vivo Dentin Microhardness beneath a Calcium-Phosphate Cement

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