“…Among the possible applications for ZnO there are: ultraviolet (UV) lasers (ZKTang et al, 1998) , light emitting diodes (LED) (Park et al, 2010) , PN junction devices (Bian et al, 2004) , transparent thin lm transistors (Carcia et al, 2006) , gas sensors (Chou et al, 2006) , and dental cements considering that its biosecurity has been proven (Nguyen et al, 2019) . Furthermore, 10 years ago it was revealed that ZnO nanoparticles have the potential to selectively kill tumor cells, performing studies with di erent tumor entities (Hanley et al, 2008;Vandebriel and De Jong, 2012;Pandurangan et al, 2016;Wahab et al, 2016;Chandrasekaran and Pandurangan, 2016;Gupta et al, 2015;Kc et al, 2016;Hassan et al, 2017), although the exact mechanism of Cytotoxicity is still subject to debate (Vandebriel and De Jong, 2012) .…”