Dental caries status and salivary properties of asthmatic children and adolescents

Paganini, Mônica; Dezan, Cássia Cilene; Bichaco, Thiago Rodrigo; Andrade, Flaviana Bombarda de; Neto, Anselmo Chaves; Fernandes, Karen Barros Parron

doi:10.1111/j.1365-263x.2010.01109.x

Cited by 34 publications

(34 citation statements)

References 23 publications

(41 reference statements)

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“…The risk of dental caries in people that use asthma medications regularly has been well documented and its occurrence is mainly due to alterations in salivary parameters [Kenny and Somaya, 1989;Maguire et al, 1996;Paganini et al, 2011]. Asthma itself was considered a risk factor for dental caries by some authors [Kankaala et al, 1998;Ersin et al, 2006;Anjomshoaa et al, 2009;Stensson et al, 2010], or the medication used for asthma treatment was blamed [Ryberg et al, 1991;Kankaala et al, 1998;McDerra et al, 1998;Reddy et al, 2003;Wogelius et al, 2004;Ersin et al, 2006;Milano et al, 2006;Shashikiran et al, 2007].…”

Section: Discussionmentioning

confidence: 99%

Cariogenic Microorganisms and Oral Conditions in Asthmatic Children

Botelho¹,

Maciel

Neto³

et al. 2011

Caries Res

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This study evaluated the caries risk of asthmatic patients on the basis of mutans streptococci (MS) and lactobacilli levels in saliva samples as well as the index of oral hygiene and dental caries (DMFT index). The study population was composed of 80 asthmatic children, aged 3–15 years, who use specific medication, and 80 matched, healthy control children. The parents were interviewed about oral health-related factors. The World Health Organization criteria were used for dental examinations. The Köhler and Bratthal methodology was used to detect salivary MS levels and dilutions of saliva were done for lactobacilli counting. No differences between asthma and control groups were observed for caries prevalence in children aged 3–6 and 7–10 years, except in severe cases in the younger group. However, higher caries prevalence for permanent dentition was observed in 11- to 15-year-old asthmatic children. An increased dental biofilm was observed in the asthma group, as well as salivary levels of MS. No differences were observed in levels of lactobacilli. No statistical correlations were found between medication, frequency of treatment, method of consumption and caries experience, dental biofilm and salivary levels of MS or lactobacilli. However, there was a correlation between MS levels and treatment duration. The logistic regression revealed that MS level is an important risk factor for increased caries experience. Asthma should be evaluated as a risk factor for caries experience because it can increase the levels of MS and the dental biofilm.

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Section: Discussionmentioning

confidence: 99%

Cariogenic Microorganisms and Oral Conditions in Asthmatic Children

Botelho¹,

Maciel

Neto³

et al. 2011

Caries Res

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“…The first is considered an etiological agent of carious lesions and is able to produce (acidogenic) and tolerate (aciduric) high quantities of lactic acid, and the second is considered particularly involved in the progression of carious lesions (8,9). Mutans streptococci and lactobacilli have been correlated positively with caries prevalence and caries increment and the existence of saliva-caries relationships have been reported (1,(10)(11)(12). The aim of this study was to evaluate, in vitro, the antimicrobial effects of the proteins lactoferrin and lysozyme on reference cultures of the microorganisms Streptococcus mutans and Lactobacillus casei, using the agar diffusion and broth macrodilution methods, in order to obtain their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), individually or synergistically.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity and Synergism of Lactoferrin and Lysozyme Against Cariogenic Microorganisms

Andrade

Oliveira²,

Yoshie³

et al. 2014

Braz. Dent. J.

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The present study evaluated the antimicrobial in vitro effects of the salivary proteins lactoferrin and lysozyme on microorganisms involved in the carious process, obtaining their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Streptococcus mutans (ATCC 25175) and Lactobacillus casei (ATCC 7469) were submitted to broth macrodilution of lysozyme at 80 mg/mL and lactoferrin at 200 mg/mL. The tubes were read in a spectrophotometer after they had been incubated at 37 °C for 18 h, in a carbon dioxide chamber, in order to read the MIC. A new subculture was carried on agar plates to obtain the MBC. The agar diffusion method was also tested, using BHI agar with 100 µL of the standardized microbial inocula. Filter-paper disks soaked in 10 µL of the solutions lactoferrin (200 µg/mL) and lysozyme (80 µg/mL) were placed on the agar surface. Inhibition halos were not observed on the plates, showing the absence of the antimicrobial effects of these proteins in this method. The bactericidal and bacteriostatic effects of lysozyme on L. casei were 50.3 mg/mL and 43.1 mg/mL respectively. The bactericidal and bacteriostatic effects on S. mutans were 68.5 mg/mL and 58.7 mg/mL. Lactoferrin did not induce any inhibitory effects on any microorganism, even in the concentration of 200 mg/mL. There was not a synergic antimicrobial effect of proteins, when they were tested together, even in the concentration of 42.8 mg/mL of lysozyme and 114 mg/mL of lactoferrin (the highest values evaluated). S. mutans and L. casei were only inhibited by lysozyme, not affected by lactoferrin and by the synergic use of both proteins.

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“…Astım genellikle, bronşiyal rahatlama sağlaması için β adrenoseptör agonistleri ile tedavi edilir. β2 adrenoseptör agonisti ile tedavinin doz-yanıt iliş-kisi tükrük salgısının bozulmasıdır ve aynı zamanda bu astım hastalarında tükürük içeriği üzerinde de bir etkiye sahiptir (8). Diğer tükürük bezleri ve parotis tükürük salgılanması oranları astımlı hastalarda sırasıyla % 26 ve % 36 oranında azalmıştır (9).…”

Section: Astim Hastaliğinin Oral Sağlik üZeri̇ne Etki̇leri̇ Astım Hastalunclassified

Asthma and Oral Health in Children

Taşkın¹,

Bodrumlu²

2017

J Int Dent Sci

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ÖZAstım çocuklarda en sık görülen hastalıklardan biridir. Astım hastalığı ve tedavisinde kullanılan ilaçlar diş çürükleri, periodontal problemler, dental erozyon ve dental candida gibi birçok probleme neden olabilmektedir. Astım hastalığı-nın ağız ve diş sağlığına etkileri olduğu kadar, diş hekimliği uygulamalarının da astım hastalığı üzerine etkileri bulunmaktadır. Bu nedenle diş hekimleri astım hastalığı konusunda yeterli bilgiye sahip olmalı ve gereken önlemler altında tedavilerini gerçekleştirmelidirler.Anahtar sözcükler: Astım, Çocuk, Diş. ABSTRACTAsthma is one of the most common disease in children. Asthma and asthma medications can cause many problems such as dental caries, periodontal problems, dental erosion and dental candida. As well as its effects on oral and dental health of asthma, the practice of dentistry has effects on asthma. Therefore, dentists must perform the treatment under the measures required and should have sufficient knowledge about asthma.

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Dental caries status and salivary properties of asthmatic children and adolescents

Abstract: Although asthma can cause reduction in flow rate, the illness did not seem to influence dental caries experience in children with access to proper dental care.

Cited by 34 publications

References 23 publications

Cariogenic Microorganisms and Oral Conditions in Asthmatic Children

Cariogenic Microorganisms and Oral Conditions in Asthmatic Children

Antimicrobial Activity and Synergism of Lactoferrin and Lysozyme Against Cariogenic Microorganisms

Asthma and Oral Health in Children

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