Dengue Perimyocarditis: A Case Report

Goh, PL

doi:10.1177/102490791001700110

Cited by 6 publications

(5 citation statements)

References 10 publications

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“…There have been reports of acute myocarditis, as well as myopericarditis, pericarditis, asymptomatic myocardial dysfunction and cardiac rhythm disturbances, such as atrioventricular blocks, sinus node dysfunction, ventricular ectopic beats, atrial fibrillation, ST-segment and T-wave changes, tachycardia and bradycardia [3,[14][15][16][17][18][19]. Electrocardiogram abnormalities have been reported during the entire course of dengue.…”

Section: Casementioning

confidence: 99%

Dengue myocarditis in Singapore: two case reports

2013

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The authors report two cases of complicated dengue viral infection with acute myocarditis involving young male adults, of which one was fatal. The first case presented with typical signs of myocardial disease: chest pain and diaphoresis with myocardial depression in the electrocardiograph. The second case deteriorated rapidly and demised within the first day of admission. Histology of the heart muscles showed multiple small foci of myocyte necrosis surrounded by lymphocytes, in keeping with viral myocarditis. Both cases fulfilled the World Health Organization (WHO) diagnosis of probable dengue: the first case had positive dengue serology, both IgM and IgG at day six of illness, and the second case was polymerase chain reaction (PCR) positive for dengue and identified as serotype 2. Despite the severe outcome, both cases did not completely fulfil the criteria for dengue haemorrhagic fever (DHF). Although severe cardiac impairment is not commonly reported in dengue infection, it can be life threatening.

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Section: Casementioning

confidence: 99%

Dengue myocarditis in Singapore: two case reports

2013

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“…Secondary infection was associated with DHF cases more than DF (Table 4 ), but there was no statistical association between secondary infection and the development of DHF. According to WHO criteria, DHF patients exhibited increased capillary permeability or plasma leakage, which shifted towards DSS with signs of shortness of breath and circulatory failure [ 43 ]. Patients presents with SOBs had the higher odds (2.21) of developing the DHF.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of clinical and laboratory characteristics of dengue viral infection and risk factors of dengue hemorrhagic fever: a multi-center retrospective analysis

Riaz,

Harun,

Mallhi

et al. 2024

BMC Infect Dis

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Background Dengue Viral Infection (DVI) has become endemic in Pakistan since the first major outbreak in Karachi in 1996. Despite aggressive measures taken by relevant authorities, Pakistan has been dealing with a worsening dengue crisis for the past two decades. DHF is severe form of dengue infection which is linked with significant morbidity and mortality. Early identification of severe dengue infections can reduce the morbidity and mortality. In this context we planned current study in which we find out the different factors related with DHF as well as clinical laboratory features of DHF and compare them to DF so that patients can be best evaluated for DHF and managed accordingly at admission. Methods Retrospective study conducted over a period of 6 years (2013–2018) in two tertiary care hospitals in Pakistan. Data were collected by using a pre-structured data collection form. Data were statistically analyzed to determine the clinical and laboratory characteristics of DVI and risk factors of dengue hemorrhagic fever (DHF). Results A total 512 dengue cases (34.05 ± 15.08 years; Male 69.53%) were reviewed. Most common clinical manifestations of DVI were fever (99.60%), headache (89.1%), chills (86.5%), rigors (86.5%), myalgia (72.3%). Less common clinical manifestations were vomiting (52.5%), arthralgia (50.2%) and skin rashes (47.5%). Furthermore, nasal bleeding (44.1%), gum bleeding (32.6%), pleural effusion (13.9%) and hematuria (13.1%) were more profound clinical presentations among DHF patients. Mortality rate was 1.5% in this study. Logistic regression analysis indicated that delayed hospitalization (OR: 2.30) and diabetes mellitus (OR:2.71), shortness of breath (OR:2.21), association with risk groups i.e., living near stagnant water, travelling to endemic areas, living in endemic regions (OR:1.95), and presence of warning signs (OR:2.18) were identified as risk factors of DHF. Statistically we found that there is strong association of diabetes mellitus (DM) with DHF while the patient suffering from DM individually had higher odds (2.71) of developing DHF than patients without disease. Conclusions The current study demonstrated that the clinical and laboratory profiles of DF and DHF are significantly distinct. Significant predictors of DHF were advanced age, diabetes mellitus, ascites, pleural effusion, thick gallbladder and delayed hospitalization. The identification of these factors at early stage provides opportunities for the clinicians to identify high risk patients and to reduce dengue-related morbidity and mortality.

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“…Shah et al reported a case of DENV infection in a young female, complicated by perimyocarditis and cardiac tamponade [ 7 ]. Another case of DENV infection in a young male presenting with hypotension was diagnosed as perimyocarditis later on [ 8 ]. Our case also presented with cardiovascular symptoms, i.e., chest pain and dyspnea, despite having no risk factors for any cardiac or pulmonary disease.…”

Section: Discussionmentioning

confidence: 99%

Perimyocarditis: An Unusual Manifestation of Dengue Virus Infection

Ullah¹,

Khan²,

Ahmad³

et al. 2023

Cureus

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Dengue is a febrile viral illness transmitted by Aedes Aegypti mosquito, presenting with a range of clinical features including a mild febrile illness to a life-threatening hemorrhagic fever or shock syndrome. Additionally, dengue fever can present with atypical features with the involvement of multiple organ systems including the heart. Here, we report a case of a 35-year-old female with dengue fever who presented with chest pain and dyspnea and was diagnosed with perimyocarditis.

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Dengue Perimyocarditis: A Case Report

Cited by 6 publications

References 10 publications

Dengue myocarditis in Singapore: two case reports

Dengue myocarditis in Singapore: two case reports

Evaluation of clinical and laboratory characteristics of dengue viral infection and risk factors of dengue hemorrhagic fever: a multi-center retrospective analysis

Perimyocarditis: An Unusual Manifestation of Dengue Virus Infection

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