Dengue in the State of Rio Grande do Norte, Brazil, 2010–2012

Branco, Mário Sérgio Duarte; Sousa, Denise M. C.; Sousa, Daíse M. C.; Monteiro, Joelma D.; Costa, Diego M. P.; Junior, Renato Ferreira de Almeida; Lima, Tábata Loíse Cunha; Farias, Kléber Juvenal Silva; Medeiros, Ralfo Cavalcante de; Queiroz, Maria Goretti; Gil, Laura Helena Vega Gonzales; Fernandes, José Veríssimo; Nogueira, Rita Maria Ribeiro; Araújo, Josélio Maria Galvão de

doi:10.1111/tmi.12612

Cited by 5 publications

(3 citation statements)

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“…DENV-4 was detected in Natal right after this event, demonstrating the speed with which these viruses can be transmitted with migratory or population movement, allowing rapid dissemination of the virus once the vectors are available. In 2012, this same study reported that the circulation of only DENV-4 was confirmed [ 6 ]. Co-circulation of serotypes 1, 2 and 4 was also shown in the years 2013 and 2014, although predominantly DENV-4 [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

“…The first laboratory-confirmed cases in RN occurred in 1994. All four DENV serotypes have been found, and the frequencies of these serotypes within the population vary by geographic region of the state and year [ 6 ]. A total of 32,328 dengue cases and 40 deaths were reported in Natal Cityfrom 2011 to 2014, and within this period the highest number of cases occurred in 2012 ( S1 Fig ).…”

Section: Introductionmentioning

confidence: 99%

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Dengue virus in Aedes aegypti and Aedes albopictus in urban areas in the state of Rio Grande do Norte, Brazil: Importance of virological and entomological surveillance

et al. 2018

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BackgroundVector control remains the sole effective method to prevent dengue virus (DENV) transmission, although a vaccine for dengue has recently become available and testing of its efficacy and coverage is being performed in multiple places. Entomological surveillance is a key factor in alerting authorities to possible outbreaks, but until now natural DENV infection of mosquito populations has been scarcely used as an early warning system to monitor fluctuating prevalence of infected mosquitoes. The purpose of this study was to determine the burden of adult and larval/pupae of Aedes aegypti and Aedes albopictus with DENV in urban areas in the state of Rio Grande do Norte, Brazil.Methodology/Principal findingsImmature insect forms (larvae and pupae) were collected from April 2011 to March 2012, whereas the collection of adults was conducted along 3 years: May 2011 to April 2014. Total RNAs of the samples were extracted and the nested reverse transcriptase PCR assay for detecting and typing DENV was performed. Of the 1333 immature insects collected during the study period, 1186 (89%) were A. aegypti and 147 (11%) A. albopictus. DENV-4 was identified in pools of A. aegypti larvae. The rate of DENV infection in immature A. aegypti was expressed as MIR = 3.37. DENV wasnot detected in immature A. albopictus. A total of 1360 adult female mosquitoes of the Aedes genus were captured from May 2011 to April 2014. Of this total, 1293 were A. aegypti (95%) and 67 were A. albopictus (5%). From the 130 pools studied, 27 (20.7%) were positive for DENV. DENV-1 was identified in 2/27 (7.4%) pools; 1of A. albopictus and 1 of A. aegypti. DENV-2 was identified in only 1/27 (3.7%) A. aegypti pools. DENV-4 was the most prevalent, identified in 24/27 (88.8%) of the positive pools, with 19 being of A. aegypti and 5 of A. albopictus pools. The minimum infection rate for adults of the Aedes genus was 19.8, considering both A. aegypti and A. albopictus.Conclusions/SignificanceThis work represents the most complete study to date on the interaction between dengue viruses and Aedes mosquitoes in the State of Rio Grande do Norte, and raises important questions about a possible role of A. albopictus in the transmission of dengue virus in Brazil.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dengue virus in Aedes aegypti and Aedes albopictus in urban areas in the state of Rio Grande do Norte, Brazil: Importance of virological and entomological surveillance

et al. 2018

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“…Results from this longitudinal study reveal the dynamics of dengue epidemiology in Barbados. There are several long-term studies, mostly from south-east Asia on dengue transmission that have sought to define the dynamics of dengue epidemiology [12, 19–21]. However, more studies are required from the Caribbean to quantify the disease burden in different populations, explore the impact of DENV serotype-specific transmission on host-responses and dengue severity and measure the economic impact of dengue in this population.…”

Section: Discussionmentioning

confidence: 99%

Long-term epidemiological dynamics of dengue in Barbados – one of the English-speaking Caribbean countries

2018

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Using the dengue surveillance program, we prospectively collected data on all the suspected and confirmed cases of dengue in Barbados from 2006 to 2015. Data were analysed for demographic, seasonal and temporal dynamics of this disease in this country. The overall mean annual incidence rate of suspected and confirmed dengue over the study period was 0.49% (range 0.15%-0.99%) and 0.16% (range 0.05%-0.48%), respectively. There was a significant correlation between the mean monthly number of confirmed cases, the mean monthly rainfall and the mean monthly relative humidity percentage. Dengue in this population is predominantly an infection affecting children and young adults. The median age of the patients with both, suspected and confirmed dengue was 25 years and the highest proportion of cases was seen in the age group 0-15 years. The annual incidence rates of both the suspected and the confirmed cases showed an upward trend during the study period and this upward trend was more pronounced among children.

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Dengue Virus and Other Flaviviruses (Zika): Biology, Pathogenesis, Epidemiology, and Vaccine Development

Alves

Ángel

2017

Human Virology in Latin America

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Dengue in the State of Rio Grande do Norte, Brazil, 2010–2012

Cited by 5 publications

References 11 publications

Dengue virus in Aedes aegypti and Aedes albopictus in urban areas in the state of Rio Grande do Norte, Brazil: Importance of virological and entomological surveillance

Dengue virus in Aedes aegypti and Aedes albopictus in urban areas in the state of Rio Grande do Norte, Brazil: Importance of virological and entomological surveillance

Long-term epidemiological dynamics of dengue in Barbados – one of the English-speaking Caribbean countries

Dengue Virus and Other Flaviviruses (Zika): Biology, Pathogenesis, Epidemiology, and Vaccine Development

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