Dengue epidemic in Touba, Senegal: implications for the Grand Magal Pilgrimage for travellers

Diagne, Cheikh Tidiane; Barry, Mamadou Aliou; Bâ, Yamar; Faye, Oumar; Sall, Amadou Alpha

doi:10.1093/jtm/tay123

Cited by 26 publications

(26 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is the first report addressing the morbidity in a cohort of pilgrims at the Grand Magal. In 2018, a dengue outbreak was associated to the Grand Magal [17,18]. A cholera outbreak involving 12,135 patients in the Grand Magal area occurred in 2004-2006, with a total of 29,556 cases reported over an 18-month in the country [16].…”

Section: Discussionmentioning

confidence: 99%

Respiratory and gastrointestinal infections at the 2017 Grand Magal de Touba, Senegal: A prospective cohort survey

Hoang

Goumballa

Dao

et al. 2019

Travel Medicine and Infectious Disease

View full text Add to dashboard Cite

Background: The Grand Magal of Touba is the largest Muslim pilgrimage in Senegal with a potential for infectious disease transmission. Methods: Clinical follow-up, adherence to preventive measures and qPCR-based respiratory and gastrointestinal pathogens carriage pre-and post-Magal, were assessed. Results: 110 pilgrims from South Senegal were included. The duration of stay in Touba was 3 days. 41.8% and 14.5% pilgrims reported respiratory and gastrointestinal symptoms. Most individuals having the onset of symptoms during their stay in Touba, or soon after returning. The acquisition of rhinoviruses, coronaviruses and adenovirus was 13.0, 16.7 and 4.6% respectively and that of Streptococcus pneumoniae and Haemophilus influenzae was 3.7% and 26.9%.Acquisition of gastrointestinal viruses and parasites was low, while bacterial acquisition ranged from 2.2% for Campylobacter jejuni to 33.0% for enteropathogenic Escherichia coli. Conclusion: This preliminary study confirms that Grand Magal pilgrims are likely to be exposed to communicable disease risk as observed in other pilgrimage settings. Further study including larger numbers of pilgrims are needed to investigate potential risk factors for respiratory and gastrointestinal infections at the Grand Magal.

show abstract

Section: Discussionmentioning

confidence: 99%

Respiratory and gastrointestinal infections at the 2017 Grand Magal de Touba, Senegal: A prospective cohort survey

Hoang

Goumballa

Dao

et al. 2019

Travel Medicine and Infectious Disease

View full text Add to dashboard Cite

show abstract

“…Authors in [ 40 ] reported a high prevalence of the Zika virus antibody during a seroprevalence study in the Dielmo area (located in the Fatick region where a DENV outbreak occurred in 2018). All these previous studies, combined with the frequent molecular detection of other dengue serotypes in Senegal [ 19 , 41 , 42 ], have stressed that there is a risk of more severe dengue outbreaks in the future, manifesting antibody-dependent enhancement (ADE) as is the case for regions with serotype co-circulation [ 43 ]. Our study is the first to report the spatio-temporal dynamics of DENV-1 in Senegal.…”

Section: Discussionmentioning

confidence: 99%

Origin and Spread of the Dengue Virus Type 1, Genotype V in Senegal, 2015–2019

Dieng

Cunha

Diagne

et al. 2021

Viruses

Self Cite

View full text Add to dashboard Cite

Dengue virus (DENV) is the most widespread arthropod-borne virus, with the number and severity of outbreaks increasing worldwide in recent decades. Dengue is caused by genetically distinct serotypes, DENV-1–4. Here, we present data on DENV-1, isolated from patients with dengue fever during an outbreak in Senegal and Mali (Western Africa) in 2015–2019, that were analyzed by sequencing the envelope (E) gene. The emergence and the dynamics of DENV-1 in Western Africa were inferred by using maximum likelihood and Bayesian methods. The DENV-1 grouped into a monophyletic cluster that was closely related to those from Southeast Asia. The virus appears to have been introduced directly into Medina Gounass (Suburb of Dakar), Senegal (location probability = 0.301, posterior = 0.76). The introduction of the virus in Senegal occurred around 2014 (95% HPD = 2012.88–2014.84), and subsequently, the virus moved to regions within Senegal (e.g., Louga and Fatick), causing intense outbreaks in the subsequent years. The virus appears to have been introduced in Mali (a neighboring country) after its introduction in Senegal. In conclusion, we present evidence that the outbreak caused by DENV-1 in urban environments in Senegal and Mali after 2015 was caused by a single viral introduction from Asia.

show abstract

“…52 The WHO Emergency Committee on Zika virus decided that postponing or cancelling the Games had no public health justification, [49][50][51]53 stating that "indi vidual risks in areas of transmission are the same whether or not a mass gathering is conducted, and can be minimised by good public health measures". 50 Because Brazil is a dengueendemic country, the risk of dengue to nonimmune visitors was also a concern, 54 based on the experience from a pilgrimage in Senegal 55 and from GeoSentinel data. GeoSentinel is a global network of travel medicine providers focused on sentinel surveillance, which generates evidencebased assessments of infectious disease risks for attendees of future mass gatherings events.…”

Section: The Rio De Janeiro 2016 Summer Olympics and Paralympicsmentioning

confidence: 99%

Mass gatherings medicine: public health issues arising from mass gathering religious and sporting events

Memish

Steffen

White³

et al. 2019

The Lancet

229

184

View full text Add to dashboard Cite

Mass gathering events are associated with major public health challenges. The 2014 Lancet Series on the new discipline of mass gatherings medicine was launched at the World Health Assembly of Ministers of Health in Geneva in May, 2014. The Series covered the planning and surveillance systems used to monitor public health risks, public health threats, and experiences of health-care providers from mass gathering events in 2012 and 2013. This follow-up Review focuses on the main public health issues arising from planned mass gathering events held between 2013 and 2018. We highlight public health and research data on transmission of infectious diseases and antibioticresistant bacteria, mass casualty incidents, and non-communicable diseases, including thermal disorders. In the events discussed in this Review, the combination of a large influx of people, many from countries with outbreakprone infectious diseases, with a high degree of crowd interactions imposed substantial burdens on host countries' health systems. The detection and transmission of antibiotic-resistant bacteria in pilgrims attending the Kumbh Mela and the Hajj raise concern of possible globalisation from mass-gathering religious events. Priorities for further investments and opportunities for research into prevention, surveillance, and management of these public health issues are discussed. Search strategy and selection criteriaWe searched PubMed, Embase, Cochrane Library, and Google Scholar for English language papers that were published from a.zumla@ucl.ac.uk disorders. Priorities for further investments and oppor tunities for research into prevention, surveillance, and management of communicable and noncom municable diseases, thermal disorders, and mass casualty incidents are discussed.

show abstract

Dengue epidemic in Touba, Senegal: implications for the Grand Magal Pilgrimage for travellers

Cited by 26 publications

References 5 publications

Respiratory and gastrointestinal infections at the 2017 Grand Magal de Touba, Senegal: A prospective cohort survey

Respiratory and gastrointestinal infections at the 2017 Grand Magal de Touba, Senegal: A prospective cohort survey

Origin and Spread of the Dengue Virus Type 1, Genotype V in Senegal, 2015–2019

Mass gatherings medicine: public health issues arising from mass gathering religious and sporting events

Contact Info

Product

Resources

About