Dendrimer functionalized carbon quantum dot for selective detection of breast cancer and gene therapy

Ghosh, Santanu; Ghosal, Krishanu; Mohammad, Sk Arif; Sarkar, Kishor

doi:10.1016/j.cej.2019.05.023

Cited by 114 publications

(73 citation statements)

References 67 publications

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“…In addition, their unique fluorescence can be used for the tracking the internalization of genes. 178 , 179 Thus, CDs will be attractive as non-viral vectors in gene therapy.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

2020

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Carbon dots (CDs), as a new type of carbon-based nanomaterial, have attracted broad research interest for years, because of their diverse physicochemical properties and favorable attributes like good biocompatibility, unique optical properties, low cost, ecofriendliness, abundant functional groups (e.g., amino, hydroxyl, carboxyl), high stability, and electron mobility. In this Outlook, we comprehensively summarize the classification of CDs based on the analysis of their formation mechanism, micro-/nanostructure and property features, and describe their synthetic methods and optical properties including strong absorption, photoluminescence, and phosphorescence. Furthermore, the recent significant advances in diverse applications, including optical (sensor, anticounterfeiting), energy (light-emitting diodes, catalysis, photovoltaics, supercapacitors), and promising biomedicine, are systematically highlighted. Finally, we envisage the key issues to be challenged, future research directions, and perspectives to show a full picture of CDs-based materials.

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“…In addition, their unique fluorescence can be used for the tracking the internalization of genes. 178 , 179 Thus, CDs will be attractive as non-viral vectors in gene therapy.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

2020

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“…Additionally, the CDP3 revealed high selective determination of the Cu(II) ion with a 93% uorescence quenching efficacy and determination of the Cu ion at 2 mM concentration that may be helpful for identication of metastatic stage of the triple negative breast cancer that demonstrates high levels of Cu(II) ion. 103 Duan et al stated that synthesis of the water soluble carbon dots with high number of the carboxyl groups has been performed through citric acid and urea via an easy microwave irradiation, and the as-procured CDs exhibited the average dimension equal to 2.6 nm with the green uorescence emission and the uorescence QY as 16.7%. 104 Obtained CDs showed reasonable biocompatibility and can be readily absorbed by the cells.…”

Section: Applications Of Cqds and Gqdsmentioning

confidence: 99%

Carbon and graphene quantum dots: a review on syntheses, characterization, biological and sensing applications for neurotransmitter determination

et al. 2020

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“…Figure 3(A) shows the XRD pattern of CuInSe 2 QD prepared using G1PPT as a capping agent. Bragg's reflections for G1PPT-CuInSe 2 QD are observed in XRD pattern at 2θ values of 27,71°, 46,39°, 54,63°representing (112), (220) and (312) planes of the zinc blende metastable structure of G1PPT-CuInSe 2 [49,50]. Recently, studies have indicated that bulk CuInSe 2 usually appears in various crystal structures (i. e. cubic zinc blende (ZB), hexagonal wurtzite (WZ) and tetragonal chalcopyrite (CH).…”

Section: Crystal Structure and Particle Size Of G1ppt-cuinse 2 Qdmentioning

confidence: 99%

Electro‐photovoltaics of Polymer‐stabilized Copper–Indium Selenide Quantum Dot

et al. 2020

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Semiconducting quantum dot (QD) materials formed by the combination of groups I, III and VI elements are perceived as promising green materials with excellent photovoltaic properties, owing to their nearinfrared (NIR) remarkable range and less harmful elements. In this study electroactive~7 nm copper indium selenide quantum dot (CuInSe 2 QD) capped with generation 1 poly (propylene thiophene) dendrimer (G1PPT), was synthesised via the hot injection method. Fourier transform infrared spectroscopy (FT-IR) signatures of the dendrimer confirmed the effective functionalization of CuInSe 2 with G1PPT. Characteristic ultraviolet-visible (UV-Vis) absorption band at 784 nm and a Tauc plot band gap energy (E gd) value of 1.51 eV which indicates a very significant photovoltaic behaviour of the CuInSe 2-G1PPT QD. The cyclic voltammetrically-deduced HOMO (-5.140 eV) and LUMO (À 3.537 eV) energy levels gave an electrochemical bandgap (E el gap) value of 1.60 eV. The electron-hole Coulomb interaction energy (J e;h) was determined to be 90 MeV, which confirms that the light absorbed by CuInSe 2-G1PPT QD mainly produce photon absorption excitons, making the material highly suitable for photovoltaic application.

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Dendrimer functionalized carbon quantum dot for selective detection of breast cancer and gene therapy

Cited by 114 publications

References 67 publications

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

Carbon and graphene quantum dots: a review on syntheses, characterization, biological and sensing applications for neurotransmitter determination

Electro‐photovoltaics of Polymer‐stabilized Copper–Indium Selenide Quantum Dot

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