Dendrimer construction and macromolecular property modification via combinatorial methods

Thermal behavior of metallodendrimers possessing bis(terpyridinyl)Ru(II) connectivity and different surface functionality

“…Thermal data for metallodendrimers and their nonmetallated cousins, with respect to stability, are also notably sparse. Here we report the thermal behavior of metallodendrimers terminated, or coated, with identical functionality or with predetermined ratios of multiple functionality obtained by a combinatorial‐type treatment36, 37 of terpyridinyl‐terminated dendrimers with Ru (III) ‐based monomer mixtures. The influence of the end groups on the T g s and thermal stability is considered.…”

Parallel Combinatorial Synthesis of Glycodendrimers and Their Hydrogelation Properties

“…On the other hand, there are only a few examples of nonpolymeric molecules that form hydrogels 36,37. Only one other report deals with dendritic hydrogelators; however, these arborols were unable to gelate below concentrations of 1.0 wt% 15. It is to be expected that the parallel combinatorial synthesis of dendrimers will accelerate the design and evaluation of dendrimers targeted for other applications, and could underpin rational attempts to modulate desired features.…”

“…A few examples of such macromolecular “fine‐tuning” have been reported. Newkome and co‐workers described the synthesis and characterization of two‐directional arborols in which branched domains were connected by alkyl spacer units of differing lengths 15. It was observed that several of these arborols formed thermally reversible aqueous gels, one of which was able to gelate at concentrations as low as 1.0 wt%.…”

Multiplurifunctionalized Phosphorus Dendrimers: Selective Functionalization of P(X)CL2 Terminal Groups

“…The easiest way consists in grafting statistically several functions, 8 fluorophore. 9 We have also applied this concept to phosphorus dendrimers, for the grafting of a fluorophore 10 on a dendrimer that has immunomodulatory effects on the human immune system.…”