Dendranthema morifolium attenuated the reduction of contraction of isolated heart and cardiomyocytes induced by ischemia/reperfusion and anoxia/reoxygenation

Identification of the phenolic components of chrysanthemum flower (Chrysanthemum morifolium Ramat)

“…This flower is also widely used as a food supplement, or herb tea, and is considered a health food by many consumers (Chu, Fu, Guan, & Ye, 2004;Lai, Lim, Su, Shen, & Ong, 2007). The chrysanthemum flower contains significant amounts of flavonoids and hydroxycinnamoylquinic acids that are considered to be the biologically active components (Beninger et al, 2004;Chen, Li, Lu, Jiang, & Zeng, 2007;Clifford, Wu, Kirkpatrick, & Kuhnert, 2007;Guo, Wang, Cheng, Wen, Wang & Liang, 2008;Harborne & Baxter, 1999;Jiang, Xia, Xu, & Zheng, 2004;Kim & Lee, 2005;Lai et al, 2007;Li & Jiang, 2006;Miyazawa & Hisama, 2003;Wang, Yang, & Guo, 2008). Among them, acacetin 7-O-galactoside and apigenin 7-O-beta-D-(4"-caffeoyl) glucuronide were isolated as the anti-HIV compounds of this herb (Hu, Chen, Shi, Kilkuskie, Cheng, & Lee, 1994;Lee, Kim, & Lee, 2003).…”

Endothelium-dependent and direct relaxation induced by ethyl acetate extract from Flos Chrysanthemi in rat thoracic aorta

“…The previous study of our lab showed the water extract of FC (0.25-1.0 g/L) increased coronary flow and contractility, decreased heart rate (HR) in isolated rat heart and intact dog heart in dose-dependent manner (Department of Physiology of Zhejiang Medical University, 1978;Zhao and Ma, 1996;Jiang et al, 2004). Furthermore, water extract of FC attenuated ST-segment reduce of cardiogram induced by electrically stimulation to nerve centre (Department of Physiology of Zhejiang Medical University, 1978;Zhao and Ma, 1996) and contractile function and coronary flow decrease of isolated rat heart caused by ischemia/reperfusion (Jiang et al, 2004). It also increased coronary flow in isolated heart of rat with high level of cholesterol (Department of Physiology of Zhejiang , 1978).…”

Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel

“…has been widely used in the People's Republic of China as a health food and medicine for thousands of years. 29 It has various biological features, including anti-inflammation, 30 antioxidant activity, 31 cardiovascular protection, 32 antitumorigenesis, 33 anti-HIV, 34 and anti-aging activities. 35 It contains a wide variety of flavonoids, 36 caffeoylquinic acids, 37 chlorogenic acid, 38 phenolic acids, 39 etc, which could be used as reductants to react with silver ions and as scaffolds to direct the formation of AgNP in solution.…”