Abstract:The denaturation of calf thymus DNA aqueous solutions following x-ray radiation (x-DNA) has been investigated with the help of a rabbit antidenatured DNA antiserum. These antibodies were shown to recognize exclusively single-stranded DNA determinants on DNA molecule in double immunodiffusion analysis. By means of this method it was possible to demonstrate that increasing numbers of single-stranded DNA determinants were formed in DNA solutions exposed to increasing doses of radiation. The rabbit serum appeared … Show more
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