Demonstration of a 3D Radar‐Like SERS Sensor Micro‐ and Nanofabricated on an Optical Fiber

Xie, Zhenwei; Feng, Shengfei; Wang, Peijie; Zhang, Lisheng; Ren, Xiangshi; Cui, Lin; Zhai, Tianrui; Chen, Jie; Wang, Yonglu; Wang, Xinke; Sun, Wenfeng; Ye, Jiasheng; Han, Peng; Klar, Peter J.; Zhang, Yan

doi:10.1002/adom.201500041

Cited by 52 publications

(28 citation statements)

References 39 publications

(72 reference statements)

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“…By exploiting a similar technique, Xie and coworkers realized a 3D SERS sensor based on parabolic mirror which focuses the excitation laser light (external to the fiber) onto the surface of the SERS body directly realized on the optical fiber end. The device shows a LOD of 10 −6 M for crystal violet in ethanol, in line with performances of other SERS fiber sensors demonstrated so far .…”

Section: Lab On Tipsupporting

confidence: 88%

Lab on Fiber Technology for biological sensing applications

Vaiano

Carotenuto

Pisco

et al. 2016

Laser & Photonics Reviews

237

155

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This review presents an overview of “Lab on Fiber” technologies and devices with special focus on the design and development of advanced fiber optic nanoprobes for biological applications. Depending on the specific location where functional materials at micro and nanoscale are integrated, “Lab on Fiber Technology” is classified into three main paradigms: Lab on Tip (where functional materials are integrated onto the optical fiber tip), Lab around Fiber (where functional materials are integrated on the outer surface of optical fibers), and Lab in Fiber (where functional materials are integrated within the holey structure of specialty optical fibers). This work reviews the strategies, the main achievements and related devices developed in the “Lab on Fiber” roadmap, discussing perspectives and challenges that lie ahead, with special focus on biological sensing applications.

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Section: Lab On Tipsupporting

confidence: 88%

Lab on Fiber Technology for biological sensing applications

Vaiano

Carotenuto

Pisco

et al. 2016

Laser & Photonics Reviews

237

155

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“…A slightly different approach is followed in another reference. [ 144 ] Here, a structure for surface enhanced Raman-scattering (SERS) has been fabricated on top of a fi bre tip.…”

Section: Novel Directionsmentioning

confidence: 99%

Three‐Dimensional μ‐Printing: An Enabling Technology

Hohmann

Renner

Waller

et al. 2015

Advanced Optical Materials

150

102

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functional elements, chiral photonic crystals, photonic metamaterials and quasicrystals. With this technology becoming commercially available, [ 1 ] many novel ideas have been realized by scientists around the world. Some of these developments can already be seen as new research areas enabled by 3D µ-printing.Many excellent reviews of the underlying technology have recently been published, and we give here just a short selection. [2][3][4][5] With the present progress report we want to summarize the tremendous technological development during the last fi ve years as well as to give an overview over some vastly growing research fi elds enabled by this development. As the number of research papers based on 3D µ-printing as enabling technology is exploding, we intend to categorize the most recent developments to identify future research directions and possible novel fi elds for the years to come. Recent Technological Advances in 3D µ-PrintingFrom the fi rst proof-of-principle in 1997, [ 6 ] the µ-printing community has continuously been expanding the structuring capabilities of µ-printing systems overcoming limitations such as structuring speed, sample volume, complicated pre and post processing, as well as minimum feature size and resolution. Progress is made along two directions: First, extending the aforementioned benchmarks of µ-printing systems. Second, techniques that move µ-printed structures towards functional devices. These two directions obviously are intertwined and require interdisciplinary research efforts on new photocurable materials, complex light-matter interaction, reaction kinetics as well as processes on a molecular level infl uencing structure formation. The most infl uential technological advances are summarized in this section.Section 2.1. covers recent work leading to a tremendous increase of the capabilities of µ-printing systems. Section 2.2. describes superresolution concepts exploiting light-matter interactions to achieve smaller feature sizes and higher structural resolution. Section 2.3. reviews spatial light modulator (SLM) based laser lithography providing additional degrees of freedom by shaping the wavefront of the laser beam. Laser Sources, Scanning Devices, and Writing GeometryThe high complexity of ultrafast fs-lasers drives the community to look for alternative laser sources, leading to cost and In this progress report the development of three-dimensional µ-printing and its impact as an enabling technology onto different scientifi c fi elds is reviewed. Driven by direct laser writing via two-photon absorption, the technology has reached a level of maturity and ease of application such that 3D printing on the micrometer scale can now be considered. While the underlying technology is still developing towards higher resolution and increasing speed of fabrication, the last fi ve years have seen new fi elds rising that were obviously enabled by 3D µ-printing. Among the recent technological developments discussed in this progress report are the fi elds of super-resolution lithography ...

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“…The optical fibers carry light to and from the grippers for sensing and/or actuation and provide a means of minimally invasive microrobot delivery. Optical fibers have previously been used in conjunction with 2PP for both imaging and sensing applications, however, to date there have been no examples of fiber‐based microrobotic systems.…”

Section: Introductionmentioning

confidence: 99%

A Monolithic Force‐Sensitive 3D Microgripper Fabricated on the Tip of an Optical Fiber Using 2‐Photon Polymerization

Power

Thompson

Anastasova

et al. 2018

Small

101

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Microscale robotic devices have myriad potential applications including drug delivery, biosensing, cell manipulation, and microsurgery. In this work, a tethered, 3D, compliant grasper with an integrated force sensor is presented, the entirety of which is fabricated on the tip of an optical fiber in a single-step process using 2-photon polymerization. This gripper can prove useful for the interrogation of biological microstructures such as alveoli, villi, or even individual cells. The position of the passively actuated grasper is controlled via micromanipulation of the optical fiber, and the microrobotic device measures approximately 100 µm in length and breadth. The force estimation is achieved using optical interferometry: high-dimensional spectral readings are used to train artificial neural networks to predict the axial force exerted on/by the gripper. The design, characterization, and testing of the grasper are described and its real-time force-sensing capability with an accuracy below 2.7% of the maximum calibrated force is demonstrated.

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Demonstration of a 3D Radar‐Like SERS Sensor Micro‐ and Nanofabricated on an Optical Fiber

Cited by 52 publications

References 39 publications

Lab on Fiber Technology for biological sensing applications

Lab on Fiber Technology for biological sensing applications

Three‐Dimensional μ‐Printing: An Enabling Technology

A Monolithic Force‐Sensitive 3D Microgripper Fabricated on the Tip of an Optical Fiber Using 2‐Photon Polymerization

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