Demography and pedigree structure of an SPF colony of rhesus monkeys (<i>Macaca mulatta</i>)

Ludvico, Lisa; Slifer, Susan H.; Massey, Kristina; Mosman, Kathryn; Mohamed, Carlos; Stone, W. H.; Keeling, Matthew James; Bernacky, Bruce J.; Dyke, Bennett

doi:10.1002/ajp.2

Cited by 3 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An additional 31 females were introduced in 1980, and four males were introduced in 1985. The colony was closed to further immigration in 1985 ( 13 ).…”

Section: Resultsmentioning

confidence: 99%

MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques

Brammer

Gillespie

Tian

et al. 2018

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

SignificanceThe discovery of MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques (MLH1-rheMac HNPCC), which is an orthologue of Lynch syndrome in humans, is highly significant in the field of oncology. The hereditary nature of this disease should allow for planned cross-breeding of rhesus macaques to assess the effects of homozygous versus heterozygous MLH1 gene mutations, as well as other comutations and environmental factors that may affect the development of colon cancers. Also, the MLH1-rheMac HNPCC syndrome in rhesus macaques can serve as an important model for development of novel approaches to diagnosis and therapy of Lynch syndrome in human patients.

show abstract

“…An additional 31 females were introduced in 1980, and four males were introduced in 1985. The colony was closed to further immigration in 1985 ( 13 ).…”

Section: Resultsmentioning

confidence: 99%

MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques

Brammer

Gillespie

Tian

et al. 2018

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

show abstract

“…Therefore, significant reductions in infant mortality are important indicators or markers for beneficial management practices. Although not specifically addressing infant mortality, the only previous study of mortality in relation to SPF status, carried out at a large rhesus breeding facility in Texas, found that crude mortality was significantly reduced in a breeding population of rhesus macaques post‐conversion to SPF status, compared with the same population prior to conversion to SPF status . In the same study, it was considered due to the selection of healthier animals for SPF colony establishment or more careful clinical management related to the SPF animal selection compared with conventional management practices.…”

Section: Discussionmentioning

confidence: 99%

“…Demographic analysis plays a significant role in animal colony management, including assessment of the effectiveness of current management practices, and prediction of future population size and structure. Although there are many studies reporting demographic aspects, including infant mortality analysis in captive rhesus macaques , to date, only one published report has attempted to address these basic demographic parameters in SPF populations . Here, we report the results of a retrospective study of infant mortality in SPF rhesus macaques over a six‐year period, with comparison to non‐SPF rhesus macaques in separate but contemporary breeding populations at the CNPRC.…”

Section: Introductionmentioning

confidence: 99%

Specific‐pathogen‐free status is associated with lower infant mortality rate in rhesus macaque (Macaca mulatta) colonies at the California National Primate Research Center

Tanaka

Lerche

Farver

et al. 2013

J of Medical Primatology

View full text Add to dashboard Cite

show abstract

Vigilance has mainly a social function in a wild group of spider monkeys (Ateles geoffroyi)

Bernardi‐Gómez,

Valdivieso‐Cortadella,

Llorente

et al. 2023

American J Primatol

View full text Add to dashboard Cite

Vigilance is a widespread behavior that allows individuals to socially acquire information and/or effectively detect potential risks posed by predators and conspecifics. In this study, we aimed to investigate how social factors (i.e., subgroup size, number of males and immatures in the subgroup, presence of fission and fusion events, subgroup activity), individual characteristics (i.e., sex, presence of dependent offspring) and possible vulnerability to predation (i.e., being in smaller subgroups or lower in the canopy) explain variation in vigilance behavior in a wild group of spider monkeys (Ateles geoffroyi). We collected vigilance data during focal samples of all adults, subadults and juveniles of the group (N = 38), and ran generalized linear mixed models with a Bayesian approach. We found that the proportion of time both sexes spent in vigilance increased with subgroup size and during fusion events. Individuals also spent more time in vigilance when the subgroup was resting or socializing compared to other activities. Moreover, the proportion of time spent in vigilance increased in subgroups with more immatures. An alternative model with similar fit suggested that the proportion of time spent in vigilance increased in females when subgroups included more adult and subadult males. Overall, these results suggest that our study group mainly directed vigilance toward conspecifics (i.e., social vigilance), probably as a result of the relatively low predation pressure experienced, and contribute to the understanding of the multiple social factors affecting vigilance in group‐living primates.

show abstract

Demography and pedigree structure of an SPF colony of rhesus monkeys (Macaca mulatta)

Cited by 3 publications

References 8 publications

MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques

MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques

Specific‐pathogen‐free status is associated with lower infant mortality rate in rhesus macaque (Macaca mulatta) colonies at the California National Primate Research Center

Vigilance has mainly a social function in a wild group of spider monkeys (Ateles geoffroyi)

Contact Info

Product

Resources

About