Demographic Factors Among HIV Confirmed Blood Donors from 2013 to 2021 in Shenzhen

Wang, Song-Xing; Sun, Lingyun; Qi, Yu; Li, Tong; Li, Ran; Xu, Yunping; Zeng, Jinfeng

doi:10.2147/ijgm.s397236

Cited by 4 publications

(2 citation statements)

References 27 publications

(35 reference statements)

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“…Those concern also found in India which seroprevalence of HIV during pandemic clearly shows difference before and during pandemic, 0.03% in 2019, 0.05% in 2020, and 0.09% in 2021 [19], [20]. Some modelling conducted in China predicted HIV cases increased between 5-14% caused by pandemic [21], [22]. Restriction level and HIV cases in blood donor showed in Figure 1.…”

Section: Resultsmentioning

confidence: 62%

An increase of human immunodeficiency virus infection amongs blood donor during COVID-19 pandemic

Muflikhah¹,

Nuraini²

2023

IJPHS

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Human immunodeficiency virus (HIV) is a one of crucial concern to blood safety because of their prolonged presence in the blood. Unsafe blood transfusion from infected donor contribute to spread the virus as well. Indonesia health ministry reported that HIV infection increase significantly in 2019 to 2021, and HIV case diagnose in population still way from the prediction in 2020, only 78.7% cases reported from 90% prediction case. A retrospective cross-sectional study was conducted and collected 51,351 blood donors during COVID-19 pandemic, 2020-2021. Blood sample analyzed using serological methods to detect the present of HIV antibodies. A reactive result of HIV screening from 21,260 donor in 2020 showed 12 donors reactive (0.00056%), while in 2021 from 30,091 donor showed 42 donors reactive (0.142899%) and showed a significant different from 2020 and 2021 (p-value <0.05). The number of reactive donors increase numerously from 2020 to 2021, while total donor also increased. The level of social restriction has contribution of HIV reactive case among blood donor and showed from two years of pandemic with p-value <0.05. A significant increase of HIV infection among blood donor and the effect of restriction level to prevent COVID-19 transmission are clearly show in this study.

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Section: Resultsmentioning

confidence: 62%

An increase of human immunodeficiency virus infection amongs blood donor during COVID-19 pandemic

Muflikhah¹,

Nuraini²

2023

IJPHS

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“…HIV infection in TTIs is still one of the issues of great concern, which largely depends on the HIV prevalence among blood donors and the characteristics of HIV positive donors [14,15]. According to the report of the United Nations acquired immune de ciency syndrome(AIDS) Programme, there will be 39 million people infection with HIV in the world by 2022, including 1.3 million new infections and 630000 deaths from AIDS related diseases in 2022 [16].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and residual risk of HIV in volunteer blood donors of Zhejiang Province, China from 2018 to 2022

Zhu,

Ding,

Han

et al. 2023

Preprint

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Background: Blood safety levels have been significantly improved since nucleic acid amplification technology (NAT) testing for blood donors was carried out, but the residual risk of transfusion transmission infections still exists. Here, the prevalence of HIV and residual risk of the HIV transmission in volunteer blood donors of Zhejiang Province, China for five years after NAT implementation were evaluated. Materials and methods：All specimens and information were collected from voluntary unpaid donors at all blood services in Zhejiang Province,China from January 2018 to December 2022. HIV antibody/antigen and HIV RNA were detected by enzyme-linked immunosorbent assay and NAT. The residual risk of the HIV transmission was calculated using the incidence/window period model. Results: A total of 3,375,678 voluntary blood donors were detected, and the HIV prevalence was 9.92/100000. The HIV prevalence of blood donors in twelve blood services in Zhejiang Province were 6.11, 6.98, 7.45, 8.21, 8.36, 8.94, 9.04, 9.66, 9.73, 10.22, 11.80 and 12.47 per 100000 donors, respectively, and the difference of all blood services was not statistically significant (P>0.05).The HIV prevalence of males (15.49/100,000) was significantly higher than that of females (1.95/100,000) (P<0.05). There was no significant difference in HIV prevalence among blood donors of all different age groups( P>0.05), but the HIV prevalence in 26 to 35 age group and 18 to 25 age group were significantly higher than that in 36 to 45 age group( P<0.05).The difference in HIV prevalence between the first-time blood donors (13.65/100,000) and repeat blood donors(6.78/100,000) was statistically significant( P<0.05). From 2018 to 2022, the HIV residual risk in blood transfusion transmission was 0.266/100000. Conclusion: The prevalence of HIV among blood donors in Zhejiang Province, China is associated with age, gender and times of blood donation. The HIV residual risk in blood transfusion transmission is low in Zhejiang Province and increasing the rate of repeat blood donors is beneficial to improve blood safety.

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Prevalence and Residual Risk of HIV in Volunteer Blood Donors of Zhejiang Province, China, from 2018 to 2022

Zhu,

Ding,

Han

et al. 2024

Canadian Journal of Infectious Diseases and Medical Microbiolog

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Background. Blood safety levels have been significantly improved since the implementation of nucleic acid amplification technology (NAT) testing for blood donors. However, there remains a residual risk of transfusion transmission infections. This study aimed to evaluate the prevalence of HIV and its residual risk transmission among volunteer blood donors of Zhejiang Province, China, for five years after NAT implementation. Materials and Methods. All specimens and information were collected from voluntary unpaid donors at all blood services in Zhejiang Province, China, from January 2018 to December 2022. The HIV antibody or antigen and HIV RNA were detected using enzyme-linked immunosorbent assay and NAT, respectively. The HIV residual risk transmission was calculated using the incidence or window period model. Results. A total of 3,375,678 voluntary blood donors were detected, revealing an HIV prevalence of 9.92/100000. The HIV prevalence of blood donors in 12 blood services in Zhejiang Province was 6.11, 6.98, 7.45, 8.21, 8.36, 8.94, 9.04, 9.66, 9.73, 10.22, 11.80, and 12.47 per 100000 donors, without statistically significant difference observed among the services (p>0.05). The HIV prevalence of males (15.49/100000) was significantly higher compared to females (1.95/100000; p<0.05). There was an insignificant difference in HIV prevalence among blood donors of all different age groups (p>0.05), but the HIV prevalence in the 26–35 age group and 18–25 age group was significantly higher compared to the 36–45 age group (p<0.05). The difference in HIV prevalence between first-time blood donors (13.65/100,000) and repeat blood donors (6.78/100,000) was statistically significant (p<0.05). From 2018 to 2022, the HIV residual risk in blood transfusion transmission was 0.266/100000. Conclusion. The prevalence of HIV among blood donors in Zhejiang Province, China, is associated with age, gender, and times of blood donation. The HIV residual risk in blood transfusion transmission remains low in the province, and increasing the rate of repeat blood donors is beneficial to improve blood safety.

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Demographic Factors Among HIV Confirmed Blood Donors from 2013 to 2021 in Shenzhen

Cited by 4 publications

References 27 publications

An increase of human immunodeficiency virus infection amongs blood donor during COVID-19 pandemic

An increase of human immunodeficiency virus infection amongs blood donor during COVID-19 pandemic

Prevalence and residual risk of HIV in volunteer blood donors of Zhejiang Province, China from 2018 to 2022

Prevalence and Residual Risk of HIV in Volunteer Blood Donors of Zhejiang Province, China, from 2018 to 2022

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